Browsing by Subject "G2 Phase"

Now showing items 1-3 of 3

5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms

Schneider-Stock R.; Diab-Assef M.; Rohrbeck A.; Foltzer-Jourdainne C.; Boltze C.; Hartig R.; Schonfeld P.; Roessner A.; Gali-Muhtasib H. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3995 USA, 2005)

Methyltransferase inhibitors commonly used in clinical trials promote tumor cell death, but their detailed cytotoxic action is not yet fully understood. A deeper knowledge about their apotosis-inducing mechanisms and their ...
Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G2 checkpoint arrest

Poehlmann A.; Habold C.; Walluscheck D.; Reissig K.; Bajbouj K.; Ullrich O.; Hartig R.; Gali-Muhtasib H.; Diestel A.; Roessner A.; Schneider-Stock R. (HOBOKEN111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2011)

Besides the well-understood DNA damage response via establishment of G2 checkpoint arrest, novel studies focus on the recovery from arrest by checkpoint override to monitor cell cycle re-entry. The aim of this study was ...
EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I associated adult T-cell leukemia-lymphoma

Moarbess G.; El-Hajj H.; Kfoury Y.; El-Sabban M.E.; Lepelletier Y.; Hermine O.; Deleuze-Masquefa C.; Bonnet P.-A.; Bazarbachi A. (WASHINGTON1900 M STREET. NW SUITE 200, WASHINGTON, DC 20036 USA, 2008)

Imiquimod is an immune response modifier currently used as a topical treatment of genital warts, basal cell carcinoma, cutaneous metastasis of malignant melanoma, and vascular tumors. We developed more efficient killers ...

Now showing items 1-3 of 3

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Browsing by Subject "G2 Phase"

Browsing by Subject "G2 Phase"

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