AUB ScholarWorks

Browsing Faculty of Arts and Sciences (FAS) by Author "Hachem, Ali"

Browsing Faculty of Arts and Sciences (FAS) by Author "Hachem, Ali"

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  • A thiosemicarbazone derivative induces triple negative breast cancer cell apoptosis: possible role of miRNA-125a-5p and miRNA-181a-5p 
    El-Majzoub, Rania; Fayyad-Kazan, Mohammad; Nasr El Dine, Assaad; Makki, Rawan; Hamade, Eva; Gréé, Renè L.; Hachem, Ali; Talhouk, Rabih S.; Fayyad-kazan, Hussein; Badran, Bassam M. (Genetics Society of Korea, 2019)
    Background: Breast cancer, the most commonly diagnosed malignancy in women, accounts for the highest cancer-related deaths worldwide. Triple negative breast cancer (TNBC), lacking the expression of estrogen, progesterone ...
  • Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains 
    Hariss, Layal; Bouhadir, Kamal Hani; El-Masri, Mirvat; Roisnel, Thierry; Gréé, Renè L.; Hachem, Ali (Beilstein-Institut Zur Forderung der Chemischen Wissenschaften, 2017)
    Using an aerobic oxidative coupling, different new imidazo[1,2-a]-N-heterocycles with gem-difluroroalkyl side chains have been prepared in fair yields by the reaction of gem-difluoroenones with aminopyridines, -pyrimidines ...
  • Synthesis of Novel Fluorinated Benzofurans and Dihydrobenzofurans 
    Hariss, Layal; Bouhadir, Kamal Hani; Roisnel, Thierry; Gréé, Renè L.; Hachem, Ali (Georg Thieme Verlag, 2017)
    Starting from easily accessible propargylic fluorides an intramolecular oxa-Michael addition affords, in good yields, new gem-difluo-rodihydrobenzofurans bearing an electrophilic double bond in position 2. On these ...

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