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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Now showing items 42-51 of 51

Targeting neuroinflammation for therapeutic intervention in neurodegenerative pathologies: A role for the peptide analogue of thymulin (PAT)

Safieh-Garabedian B.; Mayasi Y.; Saade N.E. (LONDONTELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2012)

Introduction: Inflammation has a vital task in protecting the organism, but when deregulated, it can have serious pathological consequences. The central nervous system (CNS) is capable of mounting immune and inflammatory ...
The ability of phosphodiesterase-5 inhibitors sildenafil and ordonafil to reverse L-NAME induced cardiac hypertrophy in the rabbit: Possible role of calcineurin and p38

Zeidan A.; Siam A.; Al Kaabba A.; Mohammad M.; Khatib S. (OTTAWA1200 MONTREAL ROAD, BUILDING M-55, OTTAWA, ON K1A 0R6, CANADA, 2012)

Phosphodiesterase 5 inhibitors (PDE-5Is) can suppress and (or) reverse pressure overload induced myocardial hypertrophy. This study investigated the suppressive effect of 2 PDE-5Is (sildenafil and ordonafil) on N-nitro-L-arginine ...
The ICAM-1 (469 T-C) gene polymorphism but not (241 G-A) is associated with Behçet's disease in the Lebanese population

Chmaisse H.N.; Fakhoury H.A.; Salti N.N.; Makki R.F. (, 2006)

Objective: To investigate the association of the 2 intracellular adhesion molecules-1 (ICAM-1) gene polymorphisms [thymidine-cytidine (T-C) 469 and guanosine-adenosine (G-A) 241] in Behçet's disease in Lebanon. Methods: ...
The N-terminal domain of apolipoprotein B-100: Structural characterization by homology modeling

Al-Ali H.; Khachfe H.M. (, 2007)

Background. Apolipoprotein B-100 (apo B-100) stands as one of the largest proteins in humans. Its large size of 4536 amino acids hampers the production of X-ray diffraction quality crystals and hinders in-solution NMR ...
The prevalence of hypertension and its association with other cardiovascular disease risk factors in a representative sample of the Lebanese population

Tohme R.A.; Jurjus A.R.; Estephan A. (LONDONMACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2005)

Hypertension is a well-known major risk factor for cardiovascular diseases. This study has been designed to assess the prevalence of hypertension, its co-occurrence with other cardiovascular risk factors and its association ...
The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility

Khalil B.D.; Hanna S.; Saykali B.A.; El-Sitt S.; Nasrallah A.; Marston D.; El-Sabban M.; Hahn K.M.; Symons M.; El-Sibai M. (SAN DIEGO525 B STREET, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2014)

Malignant astrocytomas are highly invasive into adjacent and distant regions of the normal brain. Rho GTPases are small monomeric G proteins that play important roles in cytoskeleton rearrangement, cell motility, and tumor ...
The role of incretin hormones in glucagon regulation and diabetes treatment

Artinian S.B.; Al-Lafi S.M.; Boutary S.S.; Zwainy N.S.; Bikhazi A.B. (Nova Science Publishers, Inc.;, 2013)

Incretins are hormones that are secreted by the gut upon feeding; their release alerts the pancreatic islets that nutrients will come through the gastrointestinal tract and islets start priming by vagal stimulation (Boron ...
The role of NF-κB in mediating the anti-inflammatory effects of IL-10 in intestinal epithelial cells

Al-Ashy R.; Chakroun I.; El-Sabban M.E.; Homaidan F.R. (LONDON24-28 OVAL RD, LONDON NW1 7DX, ENGLAND, 2006)

In inflammatory bowel disease, cells that infiltrate the mucosa regulate intestinal epithelial cell function partly through release of pro- and anti-inflammatory cytokines. The aim of this study is to evaluate the role of ...
Thymulin related peptide attenuates inflammation in the brain induced by intracerebroventricular endotoxin injection

Safieh-Garabedian B.; Jabbur S.J.; Dardenne M.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2011)

Based on significant amount of evidence, it is now generally believed, that one underlying cause for neurodegenerative diseases, could be dysregulation in inflammatory processes. The actual mechanisms involved are not yet ...
TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation

Casey O.M.; Fang L.; Hynes P.G.; Abou-Kheir W.G.; Martin P.L.; Tillman H.S.; Petrovics G.; Awwad H.O.; Ward Y.; Lake R.; Zhang L.; Kelly K. (, 2012)

Genomic rearrangements commonly occur in many types of cancers and often initiate or alter the progression of disease. Here we describe an in vivo mouse model that recapitulates the most frequent rearrangement in prostate ...

Now showing items 42-51 of 51

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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Search AUB ScholarWorks

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All of AUB ScholarWorks

This Collection

My Account

Copyright Statement