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Browsing Biochemistry and Molecular Genetics by Author "Vanden-Abeele, Fabien"

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Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion

Capuz, Alice; Osien, Sylvain; Karnoub, Melodie Anne; Aboulouard, Soulaimane; Laurent, Estelle M.N.; Coyaud, Etienne; Raffo-Romero, Antonella; Duhamel, Marie; Bonnefond, Amélie; Derhourhi, Mehdi; Trerotola, Marco; El-Yazidi-Belkoura, Ikram; Devos, David; Zilkova, Monika; Kobeissy, Firas H.; Vanden-Abeele, Fabien; Fournier, Isabelle; Čí̌zková, Dáša; Rodet, Franck; SALZET, Michel (Springer Nature, 2023)

Using multi-omics analyses including RNAseq, RT-PCR, RACE-PCR, and shotgun proteomic with enrichment strategies, we demonstrated that newborn rat astrocytes produce neural immunoglobulin constant and variable heavy chains ...
Molecular consequences of proprotein convertase 1/3 (PC1/3) inhibition in macrophages for application to cancer immunotherapy: A proteomic study

Duhamel, Marie; Rodet, Franck; Delhem, Nadira; Vanden-Abeele, Fabien; Kobeissy, Firas H.; Nataf, Serge; Pays, Laurent; Desjardins, Roxane; Gagnon, Hugo; Wisztorski, Maxence; Fournier, Isabelle; Day, Robert; SALZET, Michel (American Society for Biochemistry and Molecular Biology Inc., 2015)

Macrophages provide the first line of host immune defense. Their activation triggers the secretion of pro-inflammatory cytokines and chemokines recruiting other immune cells. In cancer, macrophages present an M2 anti-inflammatory ...
Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies

Duhamel, Marie; Rose, Mélanie; Rodet, Franck; Murgoci, Adriana Natalia; Zografidou, Lea; Régnier-Vigouroux, Anne; Vanden-Abeele, Fabien; Kobeissy, Firas H.; Nataf, Serge; Pays, Laurent; Wisztorski, Maxence; Čí̌zková, Dáša; Fournier, Isabelle; SALZET, Michel (American Society for Biochemistry and Molecular Biology Inc., 2018)

High grade gliomas are the most common brain tumors in adult. These tumors are characterized by a high infiltration in microglial cells and macrophages. The immunosuppressive tumor environment is known to orient immune ...

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Browsing Biochemistry and Molecular Genetics by Author "Vanden-Abeele, Fabien"

Browsing Biochemistry and Molecular Genetics by Author "Vanden-Abeele, Fabien"

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