AUB ScholarWorks

Browsing Biochemistry and Molecular Genetics by Author "Viet, Sarah"

Browsing Biochemistry and Molecular Genetics by Author "Viet, Sarah"

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  • Deep targeted sequencing analysis of hot spot mutations in non-small cell lung cancer patients from the Middle Eastern population 
    Khoueiry, Pierre H.; Fakhri, Ghina B.; Akel, Reem S.; Assaad, Majd Al; Mahfouz, Rami A.R.; Khuri, Fadlo R.; Chami, Hassan A.; Petersen, Jason L.; Viet, Sarah; Davies, Gareth E.; Kadara, Humam N.; Tfayli, Arafat Hussein (AME Publishing Company, 2019)
    Background: The overall 5-year survival of lung cancer remains dismal despite the current treatment regimens. Testing for driver mutations has become routine practice for oncologists due to the presence of targeted therapy ...
  • Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes 
    Finnicum, Casey T.; Rahal, Zahraa; Hassane, Maya; Treekitkarnmongkol, Warapen; Sinjab, Ansam; Morris, Rhiannon; Liu, Yuejiang; Tang, Elizabeth L.; Viet, Sarah; Petersen, Jason L.; Lorenzi, Philip L.; Tan, Lin; Petrosino, Joseph F.; Hoffman, Kristi Louise; Fujimoto, Jyunya; Moghaddam, Seyed Javad Mirhasani; Kadara, Humam N. (MDPI, 2022)
    Microbial dysbiosis has emerged as a modulator of oncogenesis and response to therapy, particularly in lung cancer. Here, we investigate the evolution of the gut and lung microbiomes following exposure to a tobacco carcinogen. ...

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