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Browsing Experimental Pathology, Microbiology, and Immunology by Issue Date

Browsing Experimental Pathology, Microbiology, and Immunology by Issue Date

Now showing items 21-40 of 204

ATL-derived exosomes modulate mesenchymal stem cells: Potential role in leukemia progression

El-Saghir, Jamal A.; Nassar, Farah J.; Tawil, Nadim M.; El-Sabban, Marwan E. (BioMed Central Ltd., 2016)

Background: Exosomes are membrane nano-vesicles secreted by a multitude of cells that harbor biological constituents such as proteins, lipids, mRNA and microRNA. Exosomes can potentially transfer their cargo to other cells, ...
Genotypic and virulence characteristics of listeria monocytogenes recovered from food items in Lebanon

Haidar-Ahmad, Nathaline; Kissoyan, Kohar Annie B.; Fadlallah, Sukayna M.; el-Hajj, Rima; Saleh, Majd; Ghosn, Nada; Matar, Ghassan (Journal of Infection in Developing Countries, 2016)

Introduction: Listeria monocytogenes is the agent of listeriosis, a life threatening foodborne disease for immunocompromised patients and pregnant women. This bacterium is not routinely screened for in Lebanon and there ...
Rotavirus genotypes and vaccine effectiveness from a sentinel, hospital-based, surveillance study for three consecutive rotavirus seasons in Lebanon

Ali, Zainab; Harastani, Houda H.; Hammadi, Moza M.; Reslan, Lina; Ghanem, Soha T.; Hajar, Farah M.; Sabra, Ahmad H.; Haidar, Amjad; Inati, Adlette; Rajab, Mariam El; Fakhouri, Hassan; Ghanem, Bassam; Baasiri, Ghassan M.; Gerbaka, Bernard J.; Zaraket, Hassan; Matar, Ghassan; Dbaibo, Ghassan S. (Public Library of Science, 2016)

Introduction Globally, rotavirus (RV) is the leading cause of gastroenteritis (GE) in children. Longitudinal data about changes in RV genotype distribution and vaccine effectiveness (VE) are scarce. This study was conducted ...
Complete genome sequence of the first H5N1 avian influenza virus isolated from chickens in Lebanon in 2016

Ibrahim, Elias; Sirawan, Abeer; El-Bazzal, Bassel; Hage, Jeanne El; Said, Mounir Abi; Zaraket, Hassan; Kandeil, A. Mohamed; Ali, Mohamed Ahmed A.; Kayali, Ghazi (American Society for Microbiology, 2016)

We generated the full genome of a highly pathogenic H5N1 avian influenza virus that caused an outbreak on a chicken farm in Lebnaon in April 2016. Analysis revealed that the virus belonged to clade 2.3.2.1c that recently ...
Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon

Melhem, Nada Mohamad; Zaraket, Hassan; Kreidieh, Khalil; Ali, Zainab; Hammadi, Moza M.; Ghanem, Soha T.; Hajar, Farah M.; Haidar, Amjad; Inati, Adlette; Rajab, Mariam El; Fakhouri, Hassan; Ghanem, Bassam; Baasiri, Ghassan M.; Dbaibo, Ghassan S. (Baishideng Publishing Group Co, 2016)

AIM To assess the burden of norovirus (NoV) and to determine the diversity of circulating strains among hospitalized children in Lebanon. METHODS Stool samples were collected from children presenting with acute gastroenteritis ...
Prevalence of antimicrobial-resistant escherichia coli from raw vegetables in Lebanon

Faour-Klingbeil, Dima; Kuri, Victor M.; Fadlallah, Sukayna M.; Matar, Ghassan (Journal of Infection in Developing Countries, 2016)

Introduction: Fresh produce has been implicated in a number of documented outbreaks of foodborne illness caused by bacteria, viruses, and parasites. Shiga toxin-producing Escherichia coli (STEC) have been detected on ...
Impact of intraoperative cholangiography on postoperative morbidity and readmission: analysis of the NSQIP database

Halawani, Hamzeh M.; Tamim, Hani Mohammed; Khalifeh, Farah; Mailhac, Aurélie C.; Jamali, Faek R. (Springer New York LLC, 2016)

Background: The debate regarding the merits of routine use of intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC) continues to rage. We aim to analyze the American College of Surgeons National ...
The inhibition of Pseudomonas aeruginosa biofilm formation by micafungin and the enhancement of antimicrobial agent effectiveness in BALB/c mice

Kissoyan, Kohar Annie B.; Bazzi, Wael; Hadi, Usamah Moh D.; Matar, Ghassan (Taylor and Francis Ltd., 2016)

Abstract: Micafungin inhibits biofilm formation by impeding 1,3-β-D-glucan synthesis in Candida albicans. Since Pseudomonas aeruginosa also has 1,3-β-D-glucan in its cell wall, this study assessed the effects of antibacterial ...
Peramivir: A novel intravenous neuraminidase inhibitor for treatment of acute influenza infections

Alame, Malak M.; Massaad, Elie; Zaraket, Hassan (Frontiers Media S.A., 2016)

Peramivir is a novel cyclopentane neuraminidase inhibitor of influenza virus. It was approved by the Food and Drug Administration in December 2014 for treatment of acute uncomplicated influenza in patients 18 years and ...
Latitude of the study place and age of the patient are associated with incidence of mediastinitis and microbiology in open-heart surgery: A systematic review and meta-analysis

Abdelnoor, Michael H.; Vengen, Øystein Arild; Johansen, Odd; Sandven, Irene; Abdelnoor, Alexander Michael (Dove Medical Press Ltd, 2016)

Objective: We aimed to summarize the pooled frequency of mediastinitis following open-heart surgery caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and Gram-negative bacteria. ...
Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation

Fawaz, Lama M.; Mrad, May F.; Kazan, Jalal M.; Sayegh, Souraya; Akika, Reem; Khoury, Samia J. (Academic Press Inc., 2016)

Vitamin D is a secosteroid hormone that plays an important regulatory role in calcium homeostasis and bone metabolism. Immune cells can both produce and respond to 1,25(OH)2D3. CD4+ T cells from vitamin D receptor (VDR) ...
Update on the epidemiology of rotavirus in the Middle East and North Africa

Zaraket, Hassan; Charide, Rana; Kreidieh, Khalil; Dbaibo, Ghassan S.; Melhem, Nada Mohamad (Elsevier Ltd, 2017)

Rotavirus (RV) is the leading cause of severe acute gastroenteritis (AGE) worldwide. Consequently, we conducted a systematic literature review on articles studying RV in the 25 countries of the MENA region during the past ...
Molecular characterization and phylogenetic analysis of human influenza A viruses isolated in Iran during the 2014-2015 season

Moasser, Elham; Behzadian, Farida; Moatari, Afagh; Fotouhi, Fatemeh; Rahimi, Amir; Zaraket, Hassan; Hosseini, Seyed Younes (Springer-Verlag Wien, 2017)

Influenza A viruses are an important cause of severe infectious diseases in humans and are characterized by their fast evolution rate. Global monitoring of these viruses is critical to detect newly emerging variants during ...
Investigation of viral and bacterial enteropathogens of diarrheic sheep and goats in Medina, Saudi Arabia

Shabana, Iman Ibrahim; Bouqellah, Nahla Alsayd; Zaraket, Hassan (Malaysian Society for Parasitology, 2017)

Diarrhea is a serious problem in sheep and goat farming, causing great economic losses. Most viral and bacterial enteropathogens of diarrheic sheep and goats are considered foodborne pathogens with a potential to be zoonotic. ...
Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia

Nabbouh, Ali I.; Hleihel, Rita S.; Saliba, Jessica L.; Karam, Martin M.; Hamie, Maguy H.; Wu, Hsin Chieh J.M.; Berthier, Caroline P.; Tawil, Nadim M.; Bonnet, Pierre Antoine; Deleuze-Masquefa, Carine; El-Hajj, Hiba Ahmad (John Wiley and Sons Inc., 2017)

BACKGROUND: Nucleophosmin 1 (NPM1) is a nucleocytoplasmic shuttling protein mainly localized in the nucleolus. NPM1 is frequently mutated in acute myeloid leukemia (AML). NPM1c oligomerizes with wild-type nucleophosmin 1 ...
Resistance and clonality in Escherichia coli and Klebsiella spp. and relationship with antibiotic consumption in major Lebanese hospitals

Daoud, Ziad D.; Salem-Sokhn, Elie; Dahdouh, Elias A.; Irani, Jihad S.; Matar, Ghassan; Doron, Shira Idit (Elsevier Ltd, 2017)

Objectives Extended-spectrum β-lactamases (ESBLs) are increasingly detected globally among Escherichia coli and Klebsiella spp. Studies show a link between inappropriate use of antibiotics and resistance. In this study, ...
Characterization of astrovirus-associated gastroenteritis in hospitalized children under five years of age

Zaraket, Hassan; Abou-El-Hassan, Hadi; Kreidieh, Khalil; Soudani, Nadia Y.; Ali, Zainab; Hammadi, Moza M.; Reslan, Lina; Ghanem, Soha T.; Hajar, Farah M.; Inati, Adlette; Rajab, Mariam El; Fakhouri, Hassan; Ghanem, Bassam; Baasiri, Ghassan M.; Melhem, Nada Mohamad; Dbaibo, Ghassan S. (Elsevier B.V., 2017)

Purpose The aim of this study was to determine the incidence and genetic diversity of astrovirus (AstV) detected in children hospitalized for gastroenteritis (GE). Methods A multi-center, hospital-based surveillance study ...
Molecular epidemiology and antimicrobial resistance of Salmonella species from clinical specimens and food Items in Lebanon

Fadlallah, Sukayna M.; Shehab, Marwa; Cheaito, Katia A.; Saleh, Majd; Ghosn, Nada; Ammar, Walid S.; Hajj, Rima El; Matar, Ghassan (Journal of Infection in Developing Countries, 2017)

Introduction: Foodborne illnesses can be due to a wide range of bacteria, one of the most common being Salmonella. In this study, PulseNet International was implemented in Lebanon to identify circulating pathogens at the ...
Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance

Tang, Julians Wei Tze; Lam, Tommy Tsan Yuk; Zaraket, Hassan; Lipkin, W. Ian; Drews, Steven J.; Hatchette, Todd F.; Héraud, Jean Michel; Koopmans, Marion P.G.; Abraham, Ashta Mary; Baraket, Amal; Bialasiewicz, Seweryn; Caniza, Miguela A.; Chan, Paul Kay Sheung; Cohen, Cheryl D.; Corriveau, André; Cowling, Benjamin John; Drews, Steven J.; Echavarría, Marcela S.; Fouchier, Ron A.M.; Fraaij, Pieter L.A.; Hachette, Todd F.; Héraud, Jean Michel; Jalal, Hamid; Jennings, Lance C.; Kabanda, Alice; Kadjo, Hervé Adjé; Khanani, Rafiq M.; Koay, Evelyn Siew Chuan; Krajden, Mel; Lee, Hongkai; Lipkin, Walter Ian; Lutwama, Julius Julian; Marchant, David J.; Nishimura, Hidekazu; Nymadawa, Pagbajabyn; Pinsky, Benjamin A.; Rughooputh, Sanjiv; Rukelibuga, Joseph; Saiyed, Taslimarif; Shet, Anita S.; Sloots, Theo; Tamfum, Jean Jacques Muyembe; Tempia, Stefano; Tozer, Sarah J.; Treurnicht, F. K.; Waris, Matti E.; Watanabe, Aripuanã Sakurada Aranha; Wemakoy, Emile Okitolonda (Lancet Publishing Group, 2017)

Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human metapneumovirus, represent a considerable ...
Viral-derived complement inhibitors: current status and potential role in immunomodulation

Abou-El-Hassan, Hadi; Zaraket, Hassan (SAGE Publications Inc., 2017)

The complement system is one of the body’s major innate immune defense mechanisms in vertebrates. Its function is to detect foreign bodies and promote their elimination through opsonisation or lysis. Complement proteins ...

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Browsing Experimental Pathology, Microbiology, and Immunology by Issue Date

Browsing Experimental Pathology, Microbiology, and Immunology by Issue Date

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Copyright Statement