AUB ScholarWorks

Browsing Experimental Pathology, Microbiology, and Immunology by Subject "Zidovudine"

Browsing Experimental Pathology, Microbiology, and Immunology by Subject "Zidovudine"

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  • Adult T-Cell Leukemia: a Comprehensive Overview on Current and Promising Treatment Modalities 
    Hleihel, Rita S.; Akkouche, Abdou; Skayneh, Hala; Hermine, Olivier; Bazarbachi, Ali Abdul Hamid; El-Hajj, Hiba Ahmad (Springer, 2021)
    Purpose of the Review: Adult T-cell leukemia (ATL) is an aggressive chemo-resistant malignancy secondary to HTLV-1 retrovirus. Prognosis of ATL remains dismal. Herein, we emphasized on the current ATL treatment modalities ...
  • Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction 
    Maseko, Sibusiso B.; Brammerloo, Yasmine; Van-Molle, Inge; Sogues, Adrià; Martin, Charlotte; Gorgulla, Christoph; Plant, Estelle; Olivet, Julien; Blavier, Jeremy; Ntombela, Thandokuhle; Delvigne, Frank; Arthanari, Haribabu; El-Hajj, Hiba Ahmad; Bazarbachi, Ali Abdul Hamid; Van Lint, Carine M.; Salehi-Ashtiani, Kourosh; Remaut, Han K.; Ballet, Steven; Volkov, Alexander N.; Twizere, Jean Claude (Elsevier B.V., 2023)
    Human T-cell leukemia virus type-1 (HTLV-1) is the first pathogenic retrovirus discovered in human. Although HTLV-1-induced diseases are well-characterized and linked to the encoded Tax-1 oncoprotein, there is currently ...
  • Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells 
    El-Hajj, Hiba Ahmad; Hleihel, Rita S.; El-Sabban, Marwan E.; Bruneau, Julie; Zaatari, Ghazi S.; Cheminant, Morgane; Marçais, Ambroise; Akkouche, Abdou; Hasegawa, Hideaki; Hall, William W.; de Thȩ, Hugues B.; Hermine, Olivier; Bazarbachi, Ali Abdul Hamid (Ferrata Storti Foundation, 2021)
    Adult T-cell leukemia/lymphoma (ATL) is associated with chronic human T-cell leukemia virus type 1 infection and carries a poor prognosis. Arsenic trioxide (AS) and interferon-alpha (IFNα) together selectively trigger Tax ...

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