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Mycobacterium tuberculosis spoligotypes circulating in the Lebanese population: A retrospective study [Spoligotypes de Mycobacterium tuberculosis circulant dans la population libanaise: Une étude rétrospective]

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dc.contributor.author Bedrossian N.
dc.contributor.author Hamze M.
dc.contributor.author Rahmo A.K.
dc.contributor.author Jurjus A.
dc.contributor.author Saliba J.
dc.contributor.author Dabboussi F.
dc.contributor.author Karam W.
dc.contributor.editor
dc.date Mar-2013
dc.date.accessioned 2017-09-07T07:00:02Z
dc.date.available 2017-09-07T07:00:02Z
dc.date.issued 2013
dc.identifier
dc.identifier.isbn
dc.identifier.issn 10203397
dc.identifier.uri http://hdl.handle.net/10938/11239
dc.description.abstract Genotyping Mycobacterium tuberculosis in Lebanon on the national level may be beneficial for assessing patients and monitoring the therapeutic response to DOTS. This study aimed to characterize the spoligotypes of clinical isolates of M. tuberculosis patients collected between April 2004 and October 2005 from all Lebanese provinces. Isolates (n = 60) were cultured and identified by their biochemical characteristics. DNA extracts of these samples were amplified by PCR and genotyped by spoligotyping. Thirteen (13) patterns of M. tuberculosis complex family strains were identified: 41.6percent of the strains belonged to the T 1 family, 25.0percent to LAM 9, 10.0percent to Haarlem 3, 3.3percent to each of CAS, LAM 8, BCG and Family 36 and 1.7percent to each of Haarlem 1, LAM 10, S, M. africanum, X 1 and T 3 families. The noticeable absence of Beijing and East African Indian families was not consistent with the patterns reported in neighbouring countries. A more inclusive study of the Lebanese population is necessary to accurately identify most of the prevailing families in the country.
dc.format.extent
dc.format.extent Pages: (119-124)
dc.language English; French
dc.relation.ispartof Publication Name: Eastern Mediterranean Health Journal; Publication Year: 2013; Volume: 19; no. 2; Pages: (119-124);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Mycobacterium tuberculosis spoligotypes circulating in the Lebanese population: A retrospective study [Spoligotypes de Mycobacterium tuberculosis circulant dans la population libanaise: Une étude rétrospective]
dc.type Article
dc.contributor.affiliation Bedrossian, N., Lebanese University, Hadath Campus, Hadath, Lebanon
dc.contributor.affiliation Hamze, M., Lebanese University, Hadath Campus, Hadath, Lebanon, AZM Center for Biotechnology, Lebanese University, Tripoli, Lebanon
dc.contributor.affiliation Rahmo, A.K., National Commission of Biotechnology, Damascus, Syrian Arab Republic
dc.contributor.affiliation Jurjus, A., Department of Human Morphology, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Saliba, J., Department of Human Morphology, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Dabboussi, F., Lebanese University, Hadath Campus, Hadath, Lebanon, AZM Center for Biotechnology, Lebanese University, Tripoli, Lebanon
dc.contributor.affiliation Karam, W., Department of Biology, Lebanese University, Hadath Campus, Hadath, Lebanon
dc.contributor.authorAddress Hamze, M.; Lebanese University, Hadath Campus, Hadath, Lebanon; email: mhamze@monzerhamze.com
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Anatomy, Cell Biology and Physiological Sciences;
dc.contributor.authorDepartment Anatomy, Cell Biology and Physiological Sciences
dc.contributor.authorDivision
dc.contributor.authorEmail
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited
dc.description.citedCount
dc.description.citedTotWOSCount
dc.description.citedWOSCount
dc.format.extentCount 6
dc.identifier.articleNo
dc.identifier.coden EMHJA
dc.identifier.pubmedID 23516820
dc.identifier.scopusID 84874767741
dc.identifier.url
dc.publisher.address
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr
dc.relation.ispartOfIssue 2
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Eastern Mediterranean Health Journal
dc.relation.ispartofPubTitleAbbr East. Mediterr. Health J.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 19
dc.source.ID
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS
dc.subject.otherIndex Africa
dc.subject.otherIndex article
dc.subject.otherIndex bacterial strain
dc.subject.otherIndex bacterium culture
dc.subject.otherIndex bacterium identification
dc.subject.otherIndex bacterium isolate
dc.subject.otherIndex biochemistry
dc.subject.otherIndex China
dc.subject.otherIndex controlled study
dc.subject.otherIndex DNA extraction
dc.subject.otherIndex ethnic group
dc.subject.otherIndex family
dc.subject.otherIndex genetic variability
dc.subject.otherIndex genotyping technique
dc.subject.otherIndex human
dc.subject.otherIndex Lebanese
dc.subject.otherIndex Lebanon
dc.subject.otherIndex major clinical study
dc.subject.otherIndex Mycobacterium africanum
dc.subject.otherIndex Mycobacterium bovis
dc.subject.otherIndex Mycobacterium tuberculosis
dc.subject.otherIndex nonhuman
dc.subject.otherIndex polymerase chain reaction
dc.subject.otherIndex prevalence
dc.subject.otherIndex retrospective study
dc.subject.otherIndex spoligotyping
dc.subject.otherIndex sputum analysis
dc.subject.otherIndex Bacterial Typing Techniques
dc.subject.otherIndex Female
dc.subject.otherIndex Genotype
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Mycobacterium tuberculosis
dc.subject.otherIndex Polymerase Chain Reaction
dc.subject.otherIndex Retrospective Studies
dc.subject.otherIndex Sputum
dc.subject.otherIndex Tuberculosis, Pulmonary
dc.subject.otherKeywordPlus
dc.subject.otherWOS


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