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Aedes albopictus in Lebanon, a potential risk of arboviruses outbreak

Show simple item record Haddad N. Mousson L. Vazeille M. Chamat S. Tayeh J. Osta M.A. Failloux A.-B.
dc.contributor.editor 2012 2017-10-03T15:43:27Z 2017-10-03T15:43:27Z 2012
dc.identifier 10.1186/1471-2334-12-300
dc.identifier.issn 14712334
dc.description.abstract Background: The mosquito Aedes albopictus is undergoing a worldwide expansion with potential consequences on transmission of various arboviruses. This species has been first detected in Lebanon in 2003.Methods: We performed a phylogenetic study of Lebanese specimens and assessed their host preference by detecting human, cat, dog and chicken immunoglobulins in mosquito blood-meals. Their capacity to transmit arboviruses was investigated by providing infectious blood-meals using an artificial feeding system followed by detection of viral particles in mosquito saliva.Results: Our results suggest that Lebanese strains are part of the recent wave of Ae. albopictus expansion and are related to some European, African and North American strains. They exhibited a host preference towards humans and an important capacity to transmit arboviruses. Indeed, we showed that Ae. albopictus was able to transmit chikungunya (CHIKV), dengue (DENV) and West-Nile (WNV) viruses. At day 10 after an infectious blood-meal at a titer of 108 MID50-ml, 30percent of mosquitoes delivered an average of 515 ± 781 viral particles of CHIKV in saliva collected using a forced salivation technique and 55percent with an average of 245 ± 304 viral particles when infected with WNV. Whereas DENV was not found in saliva at day 10 post-infection (pi), an average of 174 ± 455 viral particles was detected in 38.1percent of mosquitoes tested at day 21 after an infectious blood-meal at a higher titer of 109 MID50-ml.Conclusion: These observations suggest that Ae. albopictus around Beirut is a potential vector of the three tested arboviruses. © 2012 Haddad et al.; licensee BioMed Central Ltd.
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: BMC Infectious Diseases; Publication Year: 2012; Volume: 12;
dc.source Scopus
dc.subject.other GENBANK: JX912500, JX912501, JX912502
dc.title Aedes albopictus in Lebanon, a potential risk of arboviruses outbreak
dc.type Article
dc.contributor.affiliation Haddad, N., Lebanese University, Faculty of Public Health-II, Laboratory of Immunology, Fanar, Lebanon
dc.contributor.affiliation Mousson, L., Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25-28 rue du Dr Roux, 75724, Paris cedex 15, France
dc.contributor.affiliation Vazeille, M., Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25-28 rue du Dr Roux, 75724, Paris cedex 15, France
dc.contributor.affiliation Chamat, S., Lebanese University, Faculty of Public Health-II, Laboratory of Immunology, Fanar, Lebanon
dc.contributor.affiliation Tayeh, J., Lebanese University, Faculty of Public Health-II, Laboratory of Immunology, Fanar, Lebanon
dc.contributor.affiliation Osta, M.A., Department of Biology, American University of Beirut, Bliss Street, Beirut, Lebanon
dc.contributor.affiliation Failloux, A.-B., Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25-28 rue du Dr Roux, 75724, Paris cedex 15, France
dc.contributor.authorAddress Failloux, A.-B.; Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25-28 rue du Dr Roux, 75724, Paris cedex 15, France; email:
dc.contributor.authorCorporate University: American University of Beirut; Faculty: Faculty of Arts and Sciences; Department: Biology;
dc.contributor.authorDepartment Biology
dc.contributor.faculty Faculty of Arts and Sciences
dc.contributor.authorInitials Haddad, N
dc.contributor.authorInitials Mousson, L
dc.contributor.authorInitials Vazeille, M
dc.contributor.authorInitials Chamat, S
dc.contributor.authorInitials Tayeh, J
dc.contributor.authorInitials Osta, MA
dc.contributor.authorInitials Failloux, AB
dc.contributor.authorReprintAddress Failloux, AB (reprint author), Inst Pasteur, Dept Virol Arboviruses and Insect Vectors, 25-28 Rue Dr Roux, F-75724 Paris 15, France.
dc.contributor.authorUniversity American University of Beirut
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dc.description.citedCount 1
dc.description.citedTotWOSCount 3
dc.description.citedWOSCount 2
dc.format.extentCount 1
dc.identifier.articleNo 300
dc.identifier.coden BIDMB
dc.identifier.pubmedID 23151056
dc.identifier.scopusID 84868689222
dc.publisher.address 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
dc.relation.ispartOfISOAbbr BMC Infect. Dis.
dc.relation.ispartofPubTitle BMC Infectious Diseases
dc.relation.ispartofPubTitleAbbr BMC Infect. Dis.
dc.relation.ispartOfVolume 12
dc.source.ID WOS:000312375600001
dc.type.publication Journal
dc.subject.otherChemCAS immunoglobulin, 9007-83-4
dc.subject.otherIndex immunoglobulin
dc.subject.otherIndex Aedes albopictus
dc.subject.otherIndex Arbovirus
dc.subject.otherIndex article
dc.subject.otherIndex cat
dc.subject.otherIndex chicken
dc.subject.otherIndex Chikungunya alphavirus
dc.subject.otherIndex Dengue virus
dc.subject.otherIndex DNA extraction
dc.subject.otherIndex dog
dc.subject.otherIndex enzyme linked immunosorbent assay
dc.subject.otherIndex epidemic
dc.subject.otherIndex human
dc.subject.otherIndex immunofluorescence
dc.subject.otherIndex Lebanon
dc.subject.otherIndex nonhuman
dc.subject.otherIndex phylogeny
dc.subject.otherIndex risk assessment
dc.subject.otherIndex saliva
dc.subject.otherIndex virus particle
dc.subject.otherIndex virus replication
dc.subject.otherIndex virus strain
dc.subject.otherIndex virus transmission
dc.subject.otherIndex West Nile flavivirus
dc.subject.otherIndex Aedes
dc.subject.otherIndex Animals
dc.subject.otherIndex Arbovirus Infections
dc.subject.otherIndex Arboviruses
dc.subject.otherIndex Cats
dc.subject.otherIndex Chickens
dc.subject.otherIndex Disease Outbreaks
dc.subject.otherIndex Disease Vectors
dc.subject.otherIndex Dogs
dc.subject.otherIndex Feeding Behavior
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Molecular Sequence Data
dc.subject.otherIndex Risk Assessment
dc.subject.otherIndex Sequence Analysis, DNA
dc.subject.otherKeywordPlus WEST-NILE-VIRUS
dc.subject.otherKeywordPlus HOST-FEEDING PATTERNS
dc.subject.otherKeywordPlus CHIKUNGUNYA VIRUS
dc.subject.otherKeywordPlus VECTOR COMPETENCE
dc.subject.otherKeywordPlus GENETIC-STRUCTURE
dc.subject.otherKeywordPlus UNITED-STATES
dc.subject.otherKeywordPlus INDIAN-OCEAN
dc.subject.otherKeywordPlus RAPID DETECTION
dc.subject.otherKeywordPlus DENGUE
dc.subject.otherKeywordPlus CULICIDAE
dc.subject.otherWOS Infectious Diseases

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