dc.contributor.author |
Merrifield D.L. |
dc.contributor.author |
Shaw B.J. |
dc.contributor.author |
Harper G.M. |
dc.contributor.author |
Saoud I.P. |
dc.contributor.author |
Davies S.J. |
dc.contributor.author |
Handy R.D. |
dc.contributor.author |
Henry T.B. |
dc.contributor.editor |
|
dc.date |
2013 |
dc.date.accessioned |
2017-10-03T15:43:29Z |
dc.date.available |
2017-10-03T15:43:29Z |
dc.date.issued |
2013 |
dc.identifier |
10.1016/j.envpol.2012.11.017 |
dc.identifier.isbn |
|
dc.identifier.issn |
02697491 |
dc.identifier.uri |
http://hdl.handle.net/10938/12457 |
dc.description.abstract |
Nanoparticles (NPs) can be ingested by organisms, and NPs with antimicrobial properties may disrupt beneficial endogenous microbial communities and affect organism health. Zebrafish were fed diets containing Cu-NPs or Ag-NPs (500 mg kg-1 food), or an appropriate control for 14 d. Intestinal epithelium integrity was examined by transmission electron microscopy, and microbial community structure within the intestine was assessed by denaturing gradient gel electrophoresis (DGGE) of partial 16S rRNA. No lesions were observed in intestinal epithelia; however, presence of NPs in diets changed intestinal microbial community structure. In particular, some beneficial bacterial strains (e.g., Cetobacterium somerae) were suppressed to non-detectable levels by Cu-NP exposure, and two unidentified bacterial clones from the Firmicutes phylum were sensitive (not detected) to Cu, but were present in Ag and control fish. Unique changes in zebrafish microbiome caused by exposure to Ag-NP and Cu-NP indicate that NP ingestion could affect digestive system function and organism health. © 2012 Elsevier B.V. All rights reserved. |
dc.format.extent |
|
dc.format.extent |
Pages: (157-163) |
dc.language |
English |
dc.publisher |
OXFORD |
dc.relation.ispartof |
Publication Name: Environmental Pollution; Publication Year: 2013; Volume: 174; Pages: (157-163); |
dc.relation.ispartofseries |
|
dc.relation.uri |
|
dc.source |
Scopus |
dc.subject.other |
|
dc.title |
Ingestion of metal-nanoparticle contaminated food disrupts endogenous microbiota in zebrafish (Danio rerio) |
dc.type |
Article |
dc.contributor.affiliation |
Merrifield, D.L., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom |
dc.contributor.affiliation |
Shaw, B.J., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom |
dc.contributor.affiliation |
Harper, G.M., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom |
dc.contributor.affiliation |
Saoud, I.P., American University of Beirut, Beirut, Lebanon |
dc.contributor.affiliation |
Davies, S.J., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom |
dc.contributor.affiliation |
Handy, R.D., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom |
dc.contributor.affiliation |
Henry, T.B., School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom, Center for Environmental Biotechnology, University of Tennessee, Knoxville, TN, United States, Department of Forestry, Wildlife and Fisheries, University of Tennessee, Knoxville, TN, United States |
dc.contributor.authorAddress |
Henry, T.B.; School of Biomedical and Biological Sciences, Plymouth University, 401 Davy Building, Drake Circus, Plymouth PL4 8AA, Devon, United Kingdom; email: ted.henry@plymouth.ac.uk |
dc.contributor.authorCorporate |
University: American University of Beirut; Faculty: Faculty of Arts and Sciences; Department: Biology; |
dc.contributor.authorDepartment |
Biology |
dc.contributor.authorDivision |
|
dc.contributor.authorEmail |
ted.henry@plymouth.ac.uk |
dc.contributor.faculty |
Faculty of Arts and Sciences |
dc.contributor.authorInitials |
Merrifield, DL |
dc.contributor.authorInitials |
Shaw, BJ |
dc.contributor.authorInitials |
Harper, GM |
dc.contributor.authorInitials |
Saoud, IP |
dc.contributor.authorInitials |
Davies, SJ |
dc.contributor.authorInitials |
Handy, RD |
dc.contributor.authorInitials |
Henry, TB |
dc.contributor.authorOrcidID |
Merrifield, Daniel-0000-0002-1790-2217; |
dc.contributor.authorReprintAddress |
Henry, TB (reprint author), Univ Plymouth, Sch Biomed and Biol Sci, 401 Davy Bldg, Plymouth PL4 8AA, Devon, England. |
dc.contributor.authorResearcherID |
Merrifield, Daniel-B-3747-2011; Geracitano, Laura-E-6926-2013 |
dc.contributor.authorUniversity |
American University of Beirut |
dc.description.cited |
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dc.description.citedCount |
4 |
dc.description.citedTotWOSCount |
5 |
dc.description.citedWOSCount |
5 |
dc.format.extentCount |
7 |
dc.identifier.articleNo |
|
dc.identifier.coden |
ENPOE |
dc.identifier.pubmedID |
23262071 |
dc.identifier.scopusID |
84871818445 |
dc.identifier.url |
|
dc.publisher.address |
THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
dc.relation.ispartofConference |
|
dc.relation.ispartofConferenceCode |
|
dc.relation.ispartofConferenceDate |
|
dc.relation.ispartofConferenceHosting |
|
dc.relation.ispartofConferenceLoc |
|
dc.relation.ispartofConferenceSponsor |
|
dc.relation.ispartofConferenceTitle |
|
dc.relation.ispartofFundingAgency |
|
dc.relation.ispartOfISOAbbr |
Environ. Pollut. |
dc.relation.ispartOfIssue |
|
dc.relation.ispartOfPart |
|
dc.relation.ispartofPubTitle |
Environmental Pollution |
dc.relation.ispartofPubTitleAbbr |
Environ. Pollut. |
dc.relation.ispartOfSpecialIssue |
|
dc.relation.ispartOfSuppl |
|
dc.relation.ispartOfVolume |
174 |
dc.source.ID |
WOS:000315001600021 |
dc.type.publication |
Journal |
dc.subject.otherAuthKeyword |
Endogenous microbiota |
dc.subject.otherAuthKeyword |
Intestinal epithelium integrity |
dc.subject.otherAuthKeyword |
Nanoparticles |
dc.subject.otherAuthKeyword |
Nanotoxicology |
dc.subject.otherAuthKeyword |
Zebrafish |
dc.subject.otherChemCAS |
Water Pollutants, Chemical |
dc.subject.otherIndex |
16S rRNA |
dc.subject.otherIndex |
Antimicrobial property |
dc.subject.otherIndex |
Bacterial strains |
dc.subject.otherIndex |
Danio rerio |
dc.subject.otherIndex |
Denaturing gradient gel electrophoreses (DGGE) |
dc.subject.otherIndex |
Firmicutes |
dc.subject.otherIndex |
Intestinal epithelium |
dc.subject.otherIndex |
Microbial communities |
dc.subject.otherIndex |
Microbial community structures |
dc.subject.otherIndex |
Microbiotas |
dc.subject.otherIndex |
Nanotoxicology |
dc.subject.otherIndex |
Zebrafish |
dc.subject.otherIndex |
Biology |
dc.subject.otherIndex |
Digestive system |
dc.subject.otherIndex |
Electrophoresis |
dc.subject.otherIndex |
Microorganisms |
dc.subject.otherIndex |
Nanoparticles |
dc.subject.otherIndex |
Nutrition |
dc.subject.otherIndex |
RNA |
dc.subject.otherIndex |
Silver |
dc.subject.otherIndex |
Social sciences |
dc.subject.otherIndex |
Transmission electron microscopy |
dc.subject.otherIndex |
Metal nanoparticles |
dc.subject.otherIndex |
copper nanoparticle |
dc.subject.otherIndex |
metal nanoparticle |
dc.subject.otherIndex |
RNA 16S |
dc.subject.otherIndex |
silver nanoparticle |
dc.subject.otherIndex |
bioaccumulation |
dc.subject.otherIndex |
community structure |
dc.subject.otherIndex |
copper |
dc.subject.otherIndex |
cyprinid |
dc.subject.otherIndex |
food intake |
dc.subject.otherIndex |
microbial community |
dc.subject.otherIndex |
pollution exposure |
dc.subject.otherIndex |
silver |
dc.subject.otherIndex |
toxicology |
dc.subject.otherIndex |
anaerobic bacterium |
dc.subject.otherIndex |
animal experiment |
dc.subject.otherIndex |
animal tissue |
dc.subject.otherIndex |
article |
dc.subject.otherIndex |
Cetobacterium somerae |
dc.subject.otherIndex |
community structure |
dc.subject.otherIndex |
controlled study |
dc.subject.otherIndex |
denaturing gradient gel electrophoresis |
dc.subject.otherIndex |
ecotoxicity |
dc.subject.otherIndex |
environmental exposure |
dc.subject.otherIndex |
environmental monitoring |
dc.subject.otherIndex |
food analysis |
dc.subject.otherIndex |
food contamination |
dc.subject.otherIndex |
intestine epithelium |
dc.subject.otherIndex |
intestine flora |
dc.subject.otherIndex |
microbial community |
dc.subject.otherIndex |
nanotoxicology |
dc.subject.otherIndex |
nonhuman |
dc.subject.otherIndex |
transmission electron microscopy |
dc.subject.otherIndex |
zebra fish |
dc.subject.otherIndex |
Animals |
dc.subject.otherIndex |
Bacteria |
dc.subject.otherIndex |
Eating |
dc.subject.otherIndex |
Gastrointestinal Tract |
dc.subject.otherIndex |
Metal Nanoparticles |
dc.subject.otherIndex |
Water Pollutants, Chemical |
dc.subject.otherIndex |
Zebrafish |
dc.subject.otherIndex |
Bacteria (microorganisms) |
dc.subject.otherIndex |
Cetobacterium somerae |
dc.subject.otherIndex |
Danio rerio |
dc.subject.otherIndex |
Firmicutes |
dc.subject.otherKeywordPlus |
TITANIUM-DIOXIDE NANOPARTICLES |
dc.subject.otherKeywordPlus |
RAINBOW-TROUT |
dc.subject.otherKeywordPlus |
SILVER NANOPARTICLES |
dc.subject.otherKeywordPlus |
ONCORHYNCHUS-MYKISS |
dc.subject.otherKeywordPlus |
GUT MICROBIOTA |
dc.subject.otherKeywordPlus |
COPPER NANOPARTICLES |
dc.subject.otherKeywordPlus |
ESCHERICHIA-COLI |
dc.subject.otherKeywordPlus |
ANTIBACTERIAL ACTIVITY |
dc.subject.otherKeywordPlus |
ANTIMICROBIAL ACTIVITY |
dc.subject.otherKeywordPlus |
CARBON NANOTUBES |
dc.subject.otherWOS |
Environmental Sciences |