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Modeling the contribution of lamina 5 neuronal and network dynamics to low frequency EEG phenomena

Show simple item record Karameh F.N. Dahleh M.A. Brown E.N. Massaquoi S.G.
dc.contributor.editor 2006 2017-10-04T11:07:34Z 2017-10-04T11:07:34Z 2006
dc.identifier 10.1007/s00422-006-0090-8
dc.identifier.issn 03401200
dc.description.abstract The Electroencephalogram (EEG) is an important clinical and research tool in neurophysiology. With the advent of recording techniques, new evidence is emerging on the neuronal populations and wiring in the neocortex. A main challenge is to relate the EEG generation mechanisms to the underlying circuitry of the neocortex. In this paper, we look at the principal intrinsic properties of neocortical cells in layer 5 and their network behavior in simplified simulation models to explain the emergence of several important EEG phenomena such as the alpha rhythms, slow-wave sleep oscillations, and a form of cortical seizure. The models also predict the ability of layer 5 cells to produce a resonance-like neuronal recruitment known as the augmenting response. While previous models point to deeper brain structures, such as the thalamus, as the origin of many EEG rhythms (spindles), the current model suggests that the cortical circuitry itself has intrinsic oscillatory dynamics which could account for a wide variety of EEG phenomena. © Springer-Verlag 2006.
dc.format.extent Pages: (289-310)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Biological Cybernetics; Publication Year: 2006; Volume: 95; no. 4; Pages: (289-310);
dc.source Scopus
dc.title Modeling the contribution of lamina 5 neuronal and network dynamics to low frequency EEG phenomena
dc.type Article
dc.contributor.affiliation Karameh, F.N., Department of Electrical and Computer Engineering, American University of Beirut, Beirut 1107-2020, Lebanon
dc.contributor.affiliation Dahleh, M.A., Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, United States
dc.contributor.affiliation Brown, E.N., Department of Brain and Cognitive Sciences, MIT-Harvard Division of Health Science and Technology, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, United States, Neuroscience Statistics Research Laboratory, Department of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit Street Clinics 3, Boston, MA 02114, United States
dc.contributor.affiliation Massaquoi, S.G., Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, United States, Massachusetts Institute of Technology, MIT-Harvard Division of Health Sciences and Technology, 77 Massachusetts Ave, Cambridge, MA 02139, United States
dc.contributor.authorAddress Karameh, F.N.; Department of Electrical and Computer Engineering, American University of Beirut, Beirut 1107-2020, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut; Faculty: Faculty of Engineering and Architecture; Department: Electrical and Computer Engineering;
dc.contributor.authorDepartment Electrical and Computer Engineering
dc.contributor.authorFaculty Faculty of Engineering and Architecture
dc.contributor.authorInitials Karameh, FN
dc.contributor.authorInitials Dahleh, MA
dc.contributor.authorInitials Brown, EN
dc.contributor.authorInitials Massaquoi, SG
dc.contributor.authorReprintAddress Karameh, FN (reprint author), Amer Univ Beirut, Dept Elect and Comp Engn, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut
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dc.description.citedCount 13
dc.description.citedTotWOSCount 12
dc.description.citedWOSCount 12
dc.format.extentCount 22
dc.identifier.coden BICYA
dc.identifier.pubmedID 16897093
dc.identifier.scopusID 33749334624
dc.publisher.address 233 SPRING STREET, NEW YORK, NY 10013 USA
dc.relation.ispartOfISOAbbr Biol. Cybern.
dc.relation.ispartOfIssue 4
dc.relation.ispartofPubTitle Biological Cybernetics
dc.relation.ispartofPubTitleAbbr Biol. Cybern.
dc.relation.ispartOfVolume 95
dc.source.ID WOS:000240896600001
dc.type.publication Journal
dc.subject.otherChemCAS alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid, 77521-29-0
dc.subject.otherChemCAS Excitatory Amino Acid Agonists
dc.subject.otherChemCAS Receptors, GABA
dc.subject.otherChemCAS alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, 77521-29-0
dc.subject.otherIndex Biomedical engineering
dc.subject.otherIndex Brain
dc.subject.otherIndex Cell culture
dc.subject.otherIndex Mathematical models
dc.subject.otherIndex Neural networks
dc.subject.otherIndex Neurophysiology
dc.subject.otherIndex Recording instruments
dc.subject.otherIndex Augmenting response
dc.subject.otherIndex Cortical seizure
dc.subject.otherIndex Lamina 5 neuronal dynamics
dc.subject.otherIndex Neuronal populations
dc.subject.otherIndex Oscillatory dynamics
dc.subject.otherIndex Electroencephalography
dc.subject.otherIndex 4 aminobutyric acid receptor
dc.subject.otherIndex alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid
dc.subject.otherIndex amino acid receptor stimulating agent
dc.subject.otherIndex animal
dc.subject.otherIndex article
dc.subject.otherIndex artificial neural network
dc.subject.otherIndex biological model
dc.subject.otherIndex cell membrane potential
dc.subject.otherIndex computer simulation
dc.subject.otherIndex cytology
dc.subject.otherIndex drug effect
dc.subject.otherIndex electroencephalography
dc.subject.otherIndex electrostimulation
dc.subject.otherIndex human
dc.subject.otherIndex methodology
dc.subject.otherIndex neocortex
dc.subject.otherIndex nerve cell
dc.subject.otherIndex nerve cell inhibition
dc.subject.otherIndex nonlinear system
dc.subject.otherIndex physiology
dc.subject.otherIndex radiation exposure
dc.subject.otherIndex alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
dc.subject.otherIndex Animals
dc.subject.otherIndex Computer Simulation
dc.subject.otherIndex Electric Stimulation
dc.subject.otherIndex Electroencephalography
dc.subject.otherIndex Excitatory Amino Acid Agonists
dc.subject.otherIndex Humans
dc.subject.otherIndex Membrane Potentials
dc.subject.otherIndex Models, Neurological
dc.subject.otherIndex Neocortex
dc.subject.otherIndex Neural Inhibition
dc.subject.otherIndex Neural Networks (Computer)
dc.subject.otherIndex Neurons
dc.subject.otherIndex Nonlinear Dynamics
dc.subject.otherIndex Receptors, GABA
dc.subject.otherKeywordPlus PRIMARY SOMATOSENSORY CORTEX
dc.subject.otherKeywordPlus SHORT-TERM PLASTICITY
dc.subject.otherKeywordPlus RAT BARREL CORTEX
dc.subject.otherKeywordPlus LAYER-V NEURONS
dc.subject.otherKeywordPlus IN-VIVO
dc.subject.otherKeywordPlus SYNCHRONIZED OSCILLATIONS
dc.subject.otherKeywordPlus SPATIOTEMPORAL PROPERTIES
dc.subject.otherKeywordPlus AUGMENTING RESPONSES
dc.subject.otherWOS Computer Science, Cybernetics
dc.subject.otherWOS Neurosciences

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