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Propofol 2 mg-kg is superior to propofol 1 mg-kg for tracheal intubation in children during sevoflurane induction

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dc.contributor.author Siddik-Sayyid S.M.
dc.contributor.author Taha S.K.
dc.contributor.author Aouad M.T.
dc.contributor.author Abdallah F.W.
dc.contributor.author Al Alami A.A.
dc.contributor.author Kanazi G.E.
dc.contributor.editor
dc.date May-2011
dc.date.accessioned 2017-10-05T15:29:09Z
dc.date.available 2017-10-05T15:29:09Z
dc.date.issued 2011
dc.identifier 10.1111/j.1399-6576.2011.02423.x
dc.identifier.isbn
dc.identifier.issn 00015172
dc.identifier.uri http://hdl.handle.net/10938/15118
dc.description.abstract Background: Propofol has been used to facilitate tracheal intubation within a short time of sevoflurane induction without a muscle relaxant in children. We compared as the primary outcome the incidence of excellent intubating conditions after 8percent sevoflurane and propofol 1 or 2 mg-kg. Methods: One hundred and four patients (2-7 years) were randomly assigned to receive propofol 1 mg-kg in group SP1 (n=53) or propofol 2 mg-kg in group SP2 (n=51) after inhalation induction using sevoflurane 8percent in oxygen. Forty-five seconds after propofol and controlled ventilation, intubating conditions were assessed using a four-point scoring system based on ease of laryngoscopy, vocal cords position, coughing, jaw relaxation and limb movement. Heart rate and systolic blood pressure were measured as baseline, after sevoflurane induction, propofol, intubation and at 2 and 5 min following intubation. Results: Three patients in group SP1 were excluded from analysis. Time from sevoflurane induction to intubation (248.9±71.3 s in group SP1 vs. 230.9±61.3 s in group SP2) and endtidal sevoflurane before intubation (5.6±1.6percent in group SP1 vs. 5.2±1.5percent in group SP2) did not differ between the two groups. The incidence of excellent intubating conditions was significantly higher in group SP2 compared with group SP1 [47-51 (92percent) vs. 28-50 (56percent)]. The incidence of acceptable intubating conditions was significantly higher in group SP2 compared with group SP1 [48-51 (94percent) vs. 35-50 (70percent)]. No hemodynamic difference was noted at any time point between the two groups. Conclusion: Propofol 2 mg-kg during 8percent sevoflurane induction resulted in a higher proportion of excellent intubating conditions compared with propofol 1 mg-kg. © 2011 The Acta Anaesthesiologica Scandinavica Foundation.
dc.format.extent
dc.format.extent Pages: (535-538)
dc.language English
dc.publisher HOBOKEN
dc.relation.ispartof Publication Name: Acta Anaesthesiologica Scandinavica; Publication Year: 2011; Volume: 55; no. 5; Pages: (535-538);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Propofol 2 mg-kg is superior to propofol 1 mg-kg for tracheal intubation in children during sevoflurane induction
dc.type Article
dc.contributor.affiliation Siddik-Sayyid, S.M., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.affiliation Taha, S.K., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.affiliation Aouad, M.T., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.affiliation Abdallah, F.W., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.affiliation Al Alami, A.A., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.affiliation Kanazi, G.E., Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon
dc.contributor.authorAddress Kanazi, G. E.; Department of Anesthesiology, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon; email: gk05@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Anesthesiology;
dc.contributor.authorDepartment Anesthesiology
dc.contributor.authorDivision
dc.contributor.authorEmail gk05@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Siddik-Sayyid, SM
dc.contributor.authorInitials Taha, SK
dc.contributor.authorInitials Aouad, MT
dc.contributor.authorInitials Abdallah, FW
dc.contributor.authorInitials Al Alami, AA
dc.contributor.authorInitials Kanazi, GE
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Kanazi, GE (reprint author), Amer Univ Beirut, Med Ctr, Dept Anesthesiol, POB 11-0236, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Aouad MT, 2003, ANESTH ANALG, V96, P1325, DOI 10.1213-01.ANE.0000061586.63978.DE; Blair JN, 2000, ANAESTHESIA, V55, P774, DOI 10.1046-j.1365-2044.2000.01470.x; Inomata S, 1996, CAN J ANAESTH, V43, P806; Lerman J, 2009, PEDIATR ANESTH, V19, P218, DOI 10.1111-j.1460-9592.2009.02935.x; LERMAN J, 1994, ANESTHESIOLOGY, V80, P814, DOI 10.1097-00000542-199404000-00014; Mencke T, 2003, ANESTHESIOLOGY, V98, P1049, DOI 10.1097-00000542-200305000-00005; Min SK, 2007, ANAESTHESIA, V62, P446, DOI 10.1111-j.1365-2044.2007.05037.x; Politis GD, 2002, ANESTH ANALG, V95, P615, DOI 10.1213-01.ANE.0000025595.88474.88; Sneyd R, 2010, BRIT J ANAESTH, V104, P535; STEYN MP, 1994, BRIT J ANAESTH, V72, P403, DOI 10.1093-bja-72.4.403; Verghese ST, 2008, ANESTH ANALG, V107, P1176, DOI 10.1213-ane.0b013e3181838e95
dc.description.citedCount 9
dc.description.citedTotWOSCount 10
dc.description.citedWOSCount 7
dc.format.extentCount 4
dc.identifier.articleNo
dc.identifier.coden AANEA
dc.identifier.pubmedID 21827440
dc.identifier.scopusID 79954563766
dc.identifier.url
dc.publisher.address 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Acta Anaesthesiol. Scand.
dc.relation.ispartOfIssue 5
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Acta Anaesthesiologica Scandinavica
dc.relation.ispartofPubTitleAbbr Acta Anaesthesiol. Scand.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 55
dc.source.ID WOS:000289365000005
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS propofol, 2078-54-8
dc.subject.otherChemCAS sevoflurane, 28523-86-6
dc.subject.otherChemCAS Anesthetics, Inhalation
dc.subject.otherChemCAS Anesthetics, Intravenous
dc.subject.otherChemCAS Methyl Ethers
dc.subject.otherChemCAS Propofol, 2078-54-8
dc.subject.otherChemCAS sevoflurane, 28523-86-6
dc.subject.otherIndex propofol
dc.subject.otherIndex sevoflurane
dc.subject.otherIndex article
dc.subject.otherIndex artificial ventilation
dc.subject.otherIndex child
dc.subject.otherIndex dose response
dc.subject.otherIndex double blind procedure
dc.subject.otherIndex drug dose comparison
dc.subject.otherIndex endotracheal intubation
dc.subject.otherIndex general anesthesia
dc.subject.otherIndex heart rate
dc.subject.otherIndex hemodynamics
dc.subject.otherIndex human
dc.subject.otherIndex laryngoscopy
dc.subject.otherIndex major clinical study
dc.subject.otherIndex preschool child
dc.subject.otherIndex priority journal
dc.subject.otherIndex randomized controlled trial
dc.subject.otherIndex school child
dc.subject.otherIndex scoring system
dc.subject.otherIndex systolic blood pressure
dc.subject.otherIndex vocal cord
dc.subject.otherIndex Anesthesia, Inhalation
dc.subject.otherIndex Anesthetics, Inhalation
dc.subject.otherIndex Anesthetics, Intravenous
dc.subject.otherIndex Blood Pressure
dc.subject.otherIndex Child
dc.subject.otherIndex Child, Preschool
dc.subject.otherIndex Dose-Response Relationship, Drug
dc.subject.otherIndex Female
dc.subject.otherIndex Heart Rate
dc.subject.otherIndex Humans
dc.subject.otherIndex Injections, Intravenous
dc.subject.otherIndex Intubation, Intratracheal
dc.subject.otherIndex Male
dc.subject.otherIndex Methyl Ethers
dc.subject.otherIndex Preanesthetic Medication
dc.subject.otherIndex Propofol
dc.subject.otherIndex Treatment Outcome
dc.subject.otherKeywordPlus REMIFENTANIL
dc.subject.otherKeywordPlus ANESTHESIA
dc.subject.otherWOS Anesthesiology


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