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Maximizing diagnostic outcomes of skin biopsy specimens

Show simple item record Sleiman R. Kurban M. Abbas O.
dc.contributor.editor Jan-2013 2017-10-05T15:32:48Z 2017-10-05T15:32:48Z 2013
dc.identifier 10.1111/j.1365-4632.2012.05731.x
dc.identifier.issn 00119059
dc.description.abstract Skin biopsy is a common dermatologic procedure that is typically required to assess cutaneous neoplasms and to evaluate indistinct skin eruptions for which a clinical differential diagnosis is considered. Although plenty of literature exists on the histopathologic features of different skin diseases, clues and methods that help maximize the diagnostic results and avoid common pitfalls in the processing of skin biopsies have received little attention. In cutaneous biopsy, interpretation is very important, as is the process of choosing the appropriate biopsy technique. As soon as the decision to perform a skin biopsy is taken and until microscopic slide evaluation occurs, multiple opportunities for error may arise, any of which may disadvantage the pathologist in efforts to reach a definitive diagnosis. Therefore, it is exceptionally important that clinicians work closely with pathologists to optimize biopsy results. The purpose of this review is to increase awareness of the potential for error in the course of obtaining and interpreting biopsy specimens. The process consists of several steps that refer to, respectively: choice of biopsy site; choice of technique; tissue fixation; tissue processing; the pathologist's interpretation; and clinicopathologic correlation. Avoiding these pitfalls may, in turn, maximize the pathologist's ability to make the correct diagnosis and thus provide better patient care. © 2013 The International Society of Dermatology.
dc.format.extent Pages: (72-78)
dc.language English
dc.publisher HOBOKEN
dc.relation.ispartof Publication Name: International Journal of Dermatology; Publication Year: 2013; Volume: 52; no. 1; Pages: (72-78);
dc.source Scopus
dc.title Maximizing diagnostic outcomes of skin biopsy specimens
dc.type Article
dc.contributor.affiliation Sleiman, R., Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Kurban, M., Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Abbas, O., Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Abbas, O.; Department of Dermatology, American University of Beirut Medical Center, PO Box 11-0236 Riad El Solh, Beirut 1107 2020, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Dermatology;
dc.contributor.authorDepartment Dermatology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Sleiman, R
dc.contributor.authorInitials Kurban, M
dc.contributor.authorInitials Abbas, O
dc.contributor.authorReprintAddress Abbas, O (reprint author), Amer Univ Beirut Med Ctr, Dept Dermatol, POB 11-0236, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Alguire PC, 1998, J GEN INTERN MED, V13, P46, DOI 10.1046-j.1525-1497.1998.00009.x; Aslani FS, 2002, J CUTAN PATHOL, V36, P734; BHAWAN J, 1983, ACTA DERM-VENEREOL, V63, P560; Eady RAJ, 2010, DERMATOL CLIN, V28, P211, DOI 10.1016-j.det.2009.12.001; Khopkar U, 2008, INDIAN J DERMATOL VE, V74, P527; Mehregan DR, 2007, INT J DERMATOL, V46, P727, DOI 10.1111-j.1365-4632.2007.03274.x; Morrison LH, 2001, DERMATOL CLIN, V19, P607; Okun MR, 1972, ARCH DERMATOL, V105, P45; Sina B, 2009, J CUTAN PATHOL, V36, P505, DOI 10.1111-j.1600-0560.2008.01175.x; Ton E, 2009, BEST PRACT RES CL RH, V23, P233, DOI 10.1016-j.berh.2009.03.004; WEIGAND DA, 1985, J AM ACAD DERMATOL, V12, P274, DOI 10.1016-S0190-9622(85)80035-9
dc.description.citedCount 1
dc.description.citedTotWOSCount 0
dc.description.citedWOSCount 0
dc.format.extentCount 7
dc.identifier.coden IJDEB
dc.identifier.pubmedID 23278612
dc.identifier.scopusID 84871686273
dc.publisher.address 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
dc.relation.ispartOfISOAbbr Int. J. Dermatol.
dc.relation.ispartOfIssue 1
dc.relation.ispartofPubTitle International Journal of Dermatology
dc.relation.ispartofPubTitleAbbr Int. J. Dermatol.
dc.relation.ispartOfVolume 52
dc.source.ID WOS:000312944600014
dc.type.publication Journal
dc.subject.otherIndex article
dc.subject.otherIndex biopsy technique
dc.subject.otherIndex curettage
dc.subject.otherIndex diagnostic accuracy
dc.subject.otherIndex diagnostic error
dc.subject.otherIndex diagnostic value
dc.subject.otherIndex histopathology
dc.subject.otherIndex human
dc.subject.otherIndex incisional biopsy
dc.subject.otherIndex laboratory diagnosis
dc.subject.otherIndex melanoma
dc.subject.otherIndex pathologist
dc.subject.otherIndex punch biopsy
dc.subject.otherIndex shave biopsy
dc.subject.otherIndex skin biopsy
dc.subject.otherIndex skin defect
dc.subject.otherIndex staining
dc.subject.otherIndex tissue fixation
dc.subject.otherIndex Biopsy
dc.subject.otherIndex Diagnosis, Differential
dc.subject.otherIndex Humans
dc.subject.otherIndex Skin
dc.subject.otherIndex Skin Diseases
dc.subject.otherIndex Specimen Handling
dc.subject.otherKeywordPlus DISEASES
dc.subject.otherWOS Dermatology

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