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Confluent and reticulated papillomatosis: Clinical and histopathological study of 10 cases from Lebanon

Show simple item record Tamraz H. Raffoul M. Kurban M. Kibbi A.-G. Abbas O.
dc.contributor.editor Jan-2013 2017-10-05T15:32:48Z 2017-10-05T15:32:48Z 2013
dc.identifier 10.1111/j.1468-3083.2011.04328.x
dc.identifier.issn 09269959
dc.description.abstract Background Confluent and reticulate papillomatosis (CRP) is a rare disorder that has mostly been described in case reports and limited case series. Studies on this condition from our region are lacking. Objective-methods To describe the clinical and histopathological findings, as well as response to treatment of all patients diagnosed with CRP at the American University of Beirut Medical Center (AUB-MC) between 1999 and 2009, and to compare our findings with those published in the literature. Results Confluent and reticulate papillomatosis was diagnosed in 10 patients (five men, five women). Mean age at diagnosis was 19 years. Duration of lesions ranged from few months to several years. Skin lesions mainly consisted of reticulated, pigmented macules, patches and plaques. The most common area of involvement was the chest in five cases. The rash was asymptomatic in eight patients. Skin biopsy specimens from all patients revealed hyperkeratosis, papillomatosis and variable acanthosis. Whereas follicular plugging was observed in nine cases, anastomosis of the rete ridges was noted in three. Periodic acid Schiff stains highlighted yeast forms in six cases. Conclusion The clinical and histopathological features of the CRP patients in our study are generally comparable to those published in the literature, with minor differences. Clinically, one case had an atypical clinical presentation, and microscopically follicular plugging was seen in the majority of cases. Yeast-like spores were seen in six cases further supporting a role of Malassezia furfur in the pathogenesis of CRP. © 2011 European Academy of Dermatology and Venereology.
dc.language English
dc.publisher HOBOKEN
dc.relation.ispartof Publication Name: Journal of the European Academy of Dermatology and Venereology; Publication Year: 2013; Volume: 27; no. 1;
dc.source Scopus
dc.title Confluent and reticulated papillomatosis: Clinical and histopathological study of 10 cases from Lebanon
dc.type Article
dc.contributor.affiliation Tamraz, H., Department of Dermatology, American University of Beirut-Medical Center, Lebanon
dc.contributor.affiliation Raffoul, M., University of Dayton, OH, United States
dc.contributor.affiliation Kurban, M., Department of Dermatology, American University of Beirut-Medical Center, Lebanon
dc.contributor.affiliation Kibbi, A.-G., Department of Dermatology, American University of Beirut-Medical Center, Lebanon
dc.contributor.affiliation Abbas, O., Department of Dermatology, American University of Beirut-Medical Center, Lebanon
dc.contributor.authorAddress Abbas, O.; Department of Dermatology, American University of Beirut-Medical CenterLebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Dermatology;
dc.contributor.authorDepartment Dermatology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Tamraz, H
dc.contributor.authorInitials Raffoul, M
dc.contributor.authorInitials Kurban, M
dc.contributor.authorInitials Kibbi, AG
dc.contributor.authorInitials Abbas, O
dc.contributor.authorReprintAddress Abbas, O (reprint author), Amer Univ Beirut, Med Ctr, Dept Dermatol, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 7
dc.description.citedTotWOSCount 6
dc.description.citedWOSCount 6
dc.identifier.coden JEAVE
dc.identifier.pubmedID 22050084
dc.identifier.scopusID 84872855943
dc.publisher.address 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
dc.relation.ispartOfISOAbbr J. Eur. Acad. Dermatol. Venereol.
dc.relation.ispartOfIssue 1
dc.relation.ispartofPubTitle Journal of the European Academy of Dermatology and Venereology
dc.relation.ispartofPubTitleAbbr J. Eur. Acad. Dermatol. Venereol.
dc.relation.ispartOfVolume 27
dc.source.ID WOS:000312655900034
dc.type.publication Journal
dc.subject.otherChemCAS isotretinoin, 4759-48-2
dc.subject.otherChemCAS itraconazole, 84625-61-6
dc.subject.otherChemCAS minocycline, 10118-90-8, 11006-27-2, 13614-98-7
dc.subject.otherChemCAS Minocycline, 10118-90-8
dc.subject.otherChemCAS Steroids
dc.subject.otherChemCAS Tretinoin, 302-79-4
dc.subject.otherIndex isotretinoin
dc.subject.otherIndex itraconazole
dc.subject.otherIndex minocycline
dc.subject.otherIndex acanthosis
dc.subject.otherIndex adolescent
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex clinical article
dc.subject.otherIndex clinical feature
dc.subject.otherIndex clinical study
dc.subject.otherIndex confluent and reticulated papillomatosis
dc.subject.otherIndex disease duration
dc.subject.otherIndex disease severity
dc.subject.otherIndex female
dc.subject.otherIndex histopathology
dc.subject.otherIndex human
dc.subject.otherIndex hyperkeratosis
dc.subject.otherIndex Lebanon
dc.subject.otherIndex low drug dose
dc.subject.otherIndex Malassezia furfur
dc.subject.otherIndex male
dc.subject.otherIndex obesity
dc.subject.otherIndex periodic acid Schiff stain
dc.subject.otherIndex priority journal
dc.subject.otherIndex pruritus
dc.subject.otherIndex rash
dc.subject.otherIndex retrospective study
dc.subject.otherIndex skin biopsy
dc.subject.otherIndex skin defect
dc.subject.otherIndex thorax
dc.subject.otherIndex treatment response
dc.subject.otherIndex Administration, Oral
dc.subject.otherIndex Administration, Topical
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Biopsy, Needle
dc.subject.otherIndex Cohort Studies
dc.subject.otherIndex Drug Therapy, Combination
dc.subject.otherIndex Female
dc.subject.otherIndex Follow-Up Studies
dc.subject.otherIndex Humans
dc.subject.otherIndex Immunohistochemistry
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Minocycline
dc.subject.otherIndex Papilloma
dc.subject.otherIndex Rare Diseases
dc.subject.otherIndex Retrospective Studies
dc.subject.otherIndex Skin Neoplasms
dc.subject.otherIndex Steroids
dc.subject.otherIndex Treatment Outcome
dc.subject.otherIndex Tretinoin
dc.subject.otherKeywordPlus GOUGEROT-CARTEAUD-SYNDROME
dc.subject.otherKeywordPlus MINOCYCLINE
dc.subject.otherKeywordPlus ISOTRETINOIN
dc.subject.otherWOS Dermatology

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