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Exposure rates to hepatitis C and G virus infections among HIV-infected patients: Evidence of efficient transmission of HGV by the sexual route

Show simple item record Ramia S. Mokhbat J. Sibai A. Klayme S. Naman R.
dc.contributor.editor 2004 2017-10-05T15:37:18Z 2017-10-05T15:37:18Z 2004
dc.identifier 10.1258/0956462041211180
dc.identifier.issn 09564624
dc.description.abstract The importance of sexual transmission in the epidemiology of hepatitis G virus (HGV) and hepatitis C virus (HCV) was evaluated in two groups of HIV-1-positive Lebanese patients. Members of one group (90 patients) were HIV-1-infected via sexual route and denied intravenous drug (IVD) use, while members of the other group (28 patients) became HIV-1-infected parenterally and confessed frequent IVD use. The overall prevalence of HGV infection was relatively high in both groups and with no statistically significant difference between them (28percent among IVD users vs 32percent among the non-IVD users) despite the fact that non-IVD users were significantly older (32.7 ± 1.7 years) than the IVD users (24.0 ± 1.4 years) (P 0.01). Conversely, there was a clear association between IVD use and HCV infection (25percent for IVD users vs 7percent for non-IVD users) despite the significantly lower age of the IVD users. These results point to the efficient transmission of HGV via the sexual route, while the transmission of HCV is mainly via the parenteral route. CD4+ lymphocyte counts were known on only 82 HIV-1-infected patients. Although the number of HGV-RNA-positive patients (three) was small compared with anti-HGV-positive patients (24), a relationship was not found between CD4+ lymphocyte counts and the presence of HGV-RNA in the HIV-1-positive patients. The role of HGV in causing significant liver disease is still under dispute.
dc.format.extent Pages: (463-466)
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: International Journal of STD and AIDS; Publication Year: 2004; Volume: 15; no. 7; Pages: (463-466);
dc.source Scopus
dc.title Exposure rates to hepatitis C and G virus infections among HIV-infected patients: Evidence of efficient transmission of HGV by the sexual route
dc.type Article
dc.contributor.affiliation Ramia, S., Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Mokhbat, J., Rizk Hospital, Beirut, Lebanon
dc.contributor.affiliation Sibai, A., Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Klayme, S., Hôtel Dieu de France Hospital, Beirut, Lebanon
dc.contributor.affiliation Naman, R., Hôtel Dieu de France Hospital, Beirut, Lebanon
dc.contributor.authorAddress Ramia, S.; Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Ramia, S
dc.contributor.authorInitials Mokhbat, J
dc.contributor.authorInitials Sibai, A
dc.contributor.authorInitials Klayme, S
dc.contributor.authorInitials Naman, R
dc.contributor.authorReprintAddress Ramia, S (reprint author), Amer Univ Beirut, Fac Hlth Sci, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 9
dc.description.citedTotWOSCount 10
dc.description.citedWOSCount 10
dc.format.extentCount 4
dc.identifier.coden INSAE
dc.identifier.pubmedID 15228731
dc.identifier.scopusID 3242719504
dc.publisher.address 1 WIMPOLE STREET, LONDON W1G 0AE, ENGLAND
dc.relation.ispartOfISOAbbr Int. J. STD AIDS
dc.relation.ispartOfIssue 7
dc.relation.ispartofPubTitle International Journal of STD and AIDS
dc.relation.ispartofPubTitleAbbr Int. J. STD AIDS
dc.relation.ispartOfVolume 15
dc.source.ID WOS:000222738300007
dc.type.publication Journal
dc.subject.otherAuthKeyword Hepatitis C virus
dc.subject.otherAuthKeyword Hepatitis G virus
dc.subject.otherAuthKeyword Human immunodeficiency virus
dc.subject.otherAuthKeyword Intravenous drug users
dc.subject.otherAuthKeyword Sexual transmission
dc.subject.otherChemCAS RNA, Viral
dc.subject.otherIndex virus RNA
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex controlled study
dc.subject.otherIndex female
dc.subject.otherIndex hepatitis C
dc.subject.otherIndex hepatitis G
dc.subject.otherIndex human
dc.subject.otherIndex Human immunodeficiency virus 1
dc.subject.otherIndex Human immunodeficiency virus infection
dc.subject.otherIndex intravenous drug abuse
dc.subject.otherIndex Lebanon
dc.subject.otherIndex liver disease
dc.subject.otherIndex lymphocyte count
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex prevalence
dc.subject.otherIndex priority journal
dc.subject.otherIndex sexual intercourse
dc.subject.otherIndex virus transmission
dc.subject.otherIndex Adult
dc.subject.otherIndex Age Distribution
dc.subject.otherIndex CD4 Lymphocyte Count
dc.subject.otherIndex Female
dc.subject.otherIndex Flaviviridae Infections
dc.subject.otherIndex GB virus C
dc.subject.otherIndex Hepatitis, Viral, Human
dc.subject.otherIndex HIV Infections
dc.subject.otherIndex HIV-1
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Prevalence
dc.subject.otherIndex RNA, Viral
dc.subject.otherIndex Sexual Behavior
dc.subject.otherIndex Substance Abuse, Intravenous
dc.subject.otherKeywordPlus INJECTING DRUG-USERS
dc.subject.otherKeywordPlus CLINICAL-IMPLICATIONS
dc.subject.otherKeywordPlus GBV-C-HGV
dc.subject.otherKeywordPlus PREVALENCE
dc.subject.otherKeywordPlus TRANSFUSION
dc.subject.otherKeywordPlus ANTIBODIES
dc.subject.otherKeywordPlus RISK
dc.subject.otherKeywordPlus RNA
dc.subject.otherKeywordPlus SEROPREVALENCE
dc.subject.otherKeywordPlus GENOTYPES
dc.subject.otherWOS Immunology
dc.subject.otherWOS Infectious Diseases

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