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Chronic hepatitis C associated with Coombs-positive hemolytic anemia

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dc.contributor.author Elhajj I.I.
dc.contributor.author Sharara A.I.
dc.contributor.author Taher A.T.
dc.contributor.editor
dc.date Sep-2004
dc.date.accessioned 2017-10-05T15:37:25Z
dc.date.available 2017-10-05T15:37:25Z
dc.date.issued 2004
dc.identifier 10.1038/sj.thj.6200400
dc.identifier.isbn
dc.identifier.issn 14664860
dc.identifier.uri http://hdl.handle.net/10938/15695
dc.description.abstract Hepatitis C virus (HCV) is a recognized cause of significant extrahepatic disease. Induction of autoimmune hemolytic anemia (AIHA) has been reported, either during or after interferon (IFN) treatment of HCV infection. We herein report a 56-year-old patient with HCV infection who developed severe Coombs-positive AIHA in the absence of treatment with IFN. Prednisone therapy was initiated, but intravenous immunoglobulins were added because of persistent hemolysis. Clinical course was complicated by rapid deterioration and the development of Creutzfeldt-Jakob disease. Having discarded other possible causes of AIHA, we suggest a possible association between AIHA and infection by HCV. © 2004 The European Hematology Association All right reserved.
dc.format.extent
dc.format.extent Pages: (364-366)
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: Hematology Journal; Publication Year: 2004; Volume: 5; no. 4; Pages: (364-366);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Chronic hepatitis C associated with Coombs-positive hemolytic anemia
dc.type Article
dc.contributor.affiliation Elhajj, I.I., Division of Hematology-Oncology, Department of Internal Medicine, American Univ. of Beirut-Med. Center, Box 113-6044, Beirut 1107 2802, Lebanon
dc.contributor.affiliation Sharara, A.I., Division of Hematology-Oncology, Department of Internal Medicine, American Univ. of Beirut-Med. Center, Box 113-6044, Beirut 1107 2802, Lebanon
dc.contributor.affiliation Taher, A.T., Division of Hematology-Oncology, Department of Internal Medicine, American Univ. of Beirut-Med. Center, Box 113-6044, Beirut 1107 2802, Lebanon
dc.contributor.authorAddress Taher, A.T.; American Univ. of Beirut-Med. Center, Box 113-6044, Beirut 1107 2802, Lebanon; email: ataher@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Hematology-Oncology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Hematology-Oncology
dc.contributor.authorEmail ataher@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Elhajj, II
dc.contributor.authorInitials Sharara, AI
dc.contributor.authorInitials Taher, AT
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Taher, AT (reprint author), Amer Univ Beirut, Ctr Med, Dept Internal Med, Div Hematol Oncol, Box 113-6044, Beirut 11072802, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited BARBOLLA L, 1993, VOX SANG, V65, P156; BJORKHOLM M, 1993, J INTERN MED, V234, P119; Chao TC, 2001, J CLIN GASTROENTEROL, V33, P232, DOI 10.1097-00004836-200109000-00014; de-la-Serna-Higuera C, 1999, J CLIN GASTROENTEROL, V28, P358, DOI 10.1097-00004836-199906000-00017; FLORES G, 1993, AM J HEMATOL, V44, P237, DOI 10.1002-ajh.2830440404; HYMAN GA, 1956, AM J MED SCI, V221, P448; JEFFERIES LC, 1994, HEMATOL ONCOL CLIN N, V8, P1087; PANUSH RS, 1973, GASTROENTEROLOGY, V64, P1015; PORTELL A, 1982, REV CLIN ESP, V64, P101; Ramos-Casals M, 2003, MEDICINE, V82, P87, DOI 10.1097-00005792-200303000-00003; Sandler SG, 2002, CURR OPIN HEMATOL, V9, P509, DOI 10.1097-01.MOH.0000034927.52450.9A; Srinivasan R, 2001, J CLIN GASTROENTEROL, V32, P245, DOI 10.1097-00004836-200103000-00015; TAKASE K, 1995, J GASTROENTEROL, V30, P795, DOI 10.1007-BF02349651; Zignego AL, 1999, J HEPATOL, V31, P369, DOI 10.1016-S0168-8278(99)80239-6
dc.description.citedCount 7
dc.description.citedTotWOSCount 5
dc.description.citedWOSCount 5
dc.format.extentCount 3
dc.identifier.articleNo
dc.identifier.coden HJEOB
dc.identifier.pubmedID 15297855
dc.identifier.scopusID 4544387822
dc.identifier.url
dc.publisher.address MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
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dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
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dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Hematol. J.
dc.relation.ispartOfIssue 4
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Hematology Journal
dc.relation.ispartofPubTitleAbbr Hematol. J.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 5
dc.source.ID WOS:000227379100012
dc.type.publication Journal
dc.subject.otherAuthKeyword Anemia
dc.subject.otherAuthKeyword Autoimmune hemolytic
dc.subject.otherAuthKeyword Chronic hepatitis C infection
dc.subject.otherAuthKeyword Creutzfeldt-Jakob disease
dc.subject.otherChemCAS erythropoietin, 11096-26-7
dc.subject.otherChemCAS folic acid, 59-30-3, 6484-89-5
dc.subject.otherChemCAS immunoglobulin, 9007-83-4
dc.subject.otherChemCAS prednisone, 53-03-2
dc.subject.otherChemCAS Hemoglobins
dc.subject.otherChemCAS Immunoglobulins, Intravenous
dc.subject.otherChemCAS Prednisone, 53-03-2
dc.subject.otherIndex erythropoietin
dc.subject.otherIndex folic acid
dc.subject.otherIndex immunoglobulin
dc.subject.otherIndex interferon
dc.subject.otherIndex prednisone
dc.subject.otherIndex add on therapy
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex autoimmune hemolytic anemia
dc.subject.otherIndex case report
dc.subject.otherIndex Coombs test
dc.subject.otherIndex Creutzfeldt Jakob disease
dc.subject.otherIndex deterioration
dc.subject.otherIndex disease course
dc.subject.otherIndex hemolysis
dc.subject.otherIndex hepatitis C
dc.subject.otherIndex Hepatitis C virus
dc.subject.otherIndex human
dc.subject.otherIndex male
dc.subject.otherIndex outcomes research
dc.subject.otherIndex Anemia, Hemolytic
dc.subject.otherIndex Coombs' Test
dc.subject.otherIndex Fatal Outcome
dc.subject.otherIndex Hemoglobins
dc.subject.otherIndex Hemolysis
dc.subject.otherIndex Hepatitis C, Chronic
dc.subject.otherIndex Humans
dc.subject.otherIndex Immunoglobulins, Intravenous
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Prednisone
dc.subject.otherKeywordPlus ALPHA-INTERFERON TREATMENT
dc.subject.otherKeywordPlus INTRAVENOUS IMMUNOGLOBULIN
dc.subject.otherKeywordPlus VIRUS-INFECTION
dc.subject.otherWOS Hematology


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