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International variations in the ischemic burden post-acute myocardial infarction: Prognostic implications

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dc.contributor.author Dakik H.A.
dc.contributor.author Abdallah M.
dc.contributor.author Karrowni W.
dc.contributor.author Alam S.
dc.contributor.author Arnaout S.
dc.contributor.author Nasrallah A.
dc.contributor.author Kobeissi L.
dc.contributor.author Mahmarian J.
dc.contributor.editor
dc.date Jan-2009
dc.date.accessioned 2017-10-05T15:37:38Z
dc.date.available 2017-10-05T15:37:38Z
dc.date.issued 2009
dc.identifier 10.1007/s12350-008-9023-3
dc.identifier.isbn
dc.identifier.issn 10713581
dc.identifier.uri http://hdl.handle.net/10938/15848
dc.description.abstract Objectives: To determine if there is a variation in the ischemic burden post-acute myocardial infarction (AMI), as assessed by myocardial perfusion imaging (MPI), between different populations in different geographic locations and to see if this variation is associated with different clinical outcomes. Methods and Results: We characterized the MPI findings in 104 stable patients who were hospitalized with AMI at the American University of Beirut Medical Center (AUBMC), a tertiary referral hospital in an East Mediterranean country and we compared them to 126 patients who were enrolled according to a similar protocol in a previous study done at Baylor College of Medicine (BCM), Houston, Texas. There were no differences between the two populations with respect to prevalence of diabetes, hypertension, smoking, the use of thrombolysis, percentage of anterior MIs, Q-wave MIs, and multivessel disease on coronary angiography. However, the quantified ischemic defect size in the BCM population was double that in the AUBMC population (12 ± 12percent vs 6 ± 8percent, P .01). This was associated with almost doubling of the 1 year event rate of death-myocardial infarction (18.3percent vs 10.6percent, P = .02) in the BCM population. Conclusion: Our study suggests that the ischemic burden post-AMI, as assessed by MPI, might vary between different populations in different geographic locations. This variation carries important prognostic implications and is associated with different patient outcomes. © American Society of Nuclear Cardiology 2008.
dc.format.extent
dc.format.extent Pages: (251-254)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Journal of Nuclear Cardiology; Publication Year: 2009; Volume: 16; no. 2; Pages: (251-254);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title International variations in the ischemic burden post-acute myocardial infarction: Prognostic implications
dc.type Article
dc.contributor.affiliation Dakik, H.A., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Abdallah, M., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Karrowni, W., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Alam, S., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Arnaout, S., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Nasrallah, A., Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Kobeissi, L., Department of Epidemiology and Population Health, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon
dc.contributor.affiliation Mahmarian, J., The Methodist Hospital, Houston, TX, United States
dc.contributor.authorAddress Dakik, H.A.; Department of Internal Medicine, American University of Beirut, P.O. Box 11-0236-A38, Beirut, Lebanon; email: hd01@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail hd01@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Dakik, HA
dc.contributor.authorInitials Abdallah, M
dc.contributor.authorInitials Karrowni, W
dc.contributor.authorInitials Alam, S
dc.contributor.authorInitials Arnaout, S
dc.contributor.authorInitials Nasrallah, A
dc.contributor.authorInitials Kobeissi, L
dc.contributor.authorInitials Mahmarian, J
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Dakik, HA (reprint author), Amer Univ Beirut, Dept Internal Med, POB 11-0236-A38, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Bild DE, 2005, CIRCULATION, V111, P1313, DOI 10.1161-01.CIR.0000157730.94423.4B; Dakik HA, 1996, CIRCULATION, V94, P2735; Dakik HA, 2005, J NUCL CARDIOL, V12, P276, DOI 10.1016-j.nuclcard.2005.01.011; Detrano R, 2008, NEW ENGL J MED, V358, P1336, DOI 10.1056-NEJMoa072100; Echols MR, 2007, AM J CARDIOL, V99, P315, DOI 10.1016-j.amjcard.2006.08.031; He ZX, 2000, CIRCULATION, V101, P244; KOLEGARD SM, 2002, J EPIDEMIOLOGY COMMU, V56, P29; MAHMARIAN JJ, 1993, CIRCULATION, V87, P1197; RUMBERGER JA, 1995, CIRCULATION, V92, P2157; Saleh SS, 2005, AM J CARDIOL, V96, P1190, DOI 10.1016-j.amjcard.2005.06.054; Yusuf S, 2004, LANCET, V364, P937, DOI 10.1016-S0140-6736(04)17018-9
dc.description.citedCount 1
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.format.extentCount 4
dc.identifier.articleNo
dc.identifier.coden JNCAE
dc.identifier.pubmedID 19159997
dc.identifier.scopusID 67649960500
dc.identifier.url
dc.publisher.address 233 SPRING ST, NEW YORK, NY 10013 USA
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dc.relation.ispartofConferenceDate
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dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr J. Nucl. Cardiol.
dc.relation.ispartOfIssue 2
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Journal of Nuclear Cardiology
dc.relation.ispartofPubTitleAbbr J. Nucl. Cardiol.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 16
dc.source.ID WOS:000264102700013
dc.type.publication Journal
dc.subject.otherAuthKeyword Acute myocardial infarction
dc.subject.otherAuthKeyword Myocardial ischemia
dc.subject.otherAuthKeyword Myocardial perfusion imaging
dc.subject.otherChemCAS acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1
dc.subject.otherChemCAS clopidogrel, 113665-84-2, 120202-66-6, 90055-48-4, 94188-84-8
dc.subject.otherIndex acetylsalicylic acid
dc.subject.otherIndex beta adrenergic receptor blocking agent
dc.subject.otherIndex clopidogrel
dc.subject.otherIndex dipeptidyl carboxypeptidase inhibitor
dc.subject.otherIndex hydroxymethylglutaryl coenzyme A reductase inhibitor
dc.subject.otherIndex acute heart infarction
dc.subject.otherIndex adult
dc.subject.otherIndex angiocardiography
dc.subject.otherIndex article
dc.subject.otherIndex blood clot lysis
dc.subject.otherIndex controlled study
dc.subject.otherIndex coronary artery disease
dc.subject.otherIndex death
dc.subject.otherIndex diabetes mellitus
dc.subject.otherIndex diagnostic imaging
dc.subject.otherIndex female
dc.subject.otherIndex geographic distribution
dc.subject.otherIndex heart muscle ischemia
dc.subject.otherIndex heart muscle perfusion
dc.subject.otherIndex human
dc.subject.otherIndex hypertension
dc.subject.otherIndex Lebanon
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex prevalence
dc.subject.otherIndex priority journal
dc.subject.otherIndex prognosis
dc.subject.otherIndex single photon emission computer tomography
dc.subject.otherIndex smoking
dc.subject.otherIndex Southern Europe
dc.subject.otherIndex tertiary health care
dc.subject.otherIndex United States
dc.subject.otherIndex university hospital
dc.subject.otherIndex comorbidity
dc.subject.otherIndex heart infarction
dc.subject.otherIndex incidence
dc.subject.otherIndex international cooperation
dc.subject.otherIndex Lebanon
dc.subject.otherIndex methodology
dc.subject.otherIndex middle aged
dc.subject.otherIndex reproducibility
dc.subject.otherIndex risk assessment
dc.subject.otherIndex risk factor
dc.subject.otherIndex scintiscanning
dc.subject.otherIndex sensitivity and specificity
dc.subject.otherIndex stunned heart muscle
dc.subject.otherIndex Comorbidity
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Incidence
dc.subject.otherIndex Internationality
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Myocardial Infarction
dc.subject.otherIndex Myocardial Stunning
dc.subject.otherIndex Prognosis
dc.subject.otherIndex Reproducibility of Results
dc.subject.otherIndex Risk Assessment
dc.subject.otherIndex Risk Factors
dc.subject.otherIndex Sensitivity and Specificity
dc.subject.otherKeywordPlus BEAM COMPUTED-TOMOGRAPHY
dc.subject.otherKeywordPlus CALCIFICATION
dc.subject.otherKeywordPlus CALCIUM
dc.subject.otherKeywordPlus TRIAL
dc.subject.otherWOS Cardiac and Cardiovascular Systems
dc.subject.otherWOS Radiology, Nuclear Medicine and Medical Imaging


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