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Levels of non-transferrin-bound iron as an index of iron overload in patients with thalassaemia intermedia

Show simple item record Taher A. Musallam K.M. El Rassi F. Duca L. Inati A. Koussa S. Cappellini M.D.
dc.contributor.editor Sep-2009 2017-10-05T15:37:39Z 2017-10-05T15:37:39Z 2009
dc.identifier 10.1111/j.1365-2141.2009.07810.x
dc.identifier.issn 00071048
dc.description.abstract Non-transferrin-bound iron (NTBI) was evaluated as an index of iron overload in a cross-sectional randomised study in 74 non-transfused patients with thalassaemia intermedia (TI). Mean NTBI (2.92 ± 3.43 μmol-l), serum ferritin (1023 ± 780 ng-ml) and liver iron concentration (LIC; 9.0 ± 7.4 mg Fe-g dry weight) were increased above reference-range levels. Significant positive correlations occurred between mean NTBI and LIC (Pearson correlation 0.36; P = 0.002) and serum ferritin (Pearson correlation 0.421; P 0.0001); with higher levels observed in splenectomised patients. NTBI assessment has potential as a simple reliable approach to determining iron status in TI. © 2009 Blackwell Publishing Ltd.
dc.format.extent Pages: (569-572)
dc.language English
dc.publisher MALDEN
dc.relation.ispartof Publication Name: British Journal of Haematology; Publication Year: 2009; Volume: 146; no. 5; Pages: (569-572);
dc.source Scopus
dc.title Levels of non-transferrin-bound iron as an index of iron overload in patients with thalassaemia intermedia
dc.type Article
dc.contributor.affiliation Taher, A., Department of Internal Medicine, Haematology-Oncology Division, American University of Beirut Medical Centre, Beirut 1107 2020, Lebanon, American University of Beirut, Beirut, Lebanon, Chronic Cancer Care Centre, Hazmieh, Lebanon
dc.contributor.affiliation Musallam, K.M., American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation El Rassi, F., American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Duca, L., Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy
dc.contributor.affiliation Inati, A., Chronic Cancer Care Centre, Hazmieh, Lebanon, Rafik Hariri University Hospital, Beirut, Lebanon
dc.contributor.affiliation Koussa, S., Chronic Cancer Care Centre, Hazmieh, Lebanon
dc.contributor.affiliation Cappellini, M.D., Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy
dc.contributor.authorAddress Taher, A.; Department of Internal Medicine, Haematology-Oncology Division, American University of Beirut Medical Centre, Beirut 1107 2020, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Taher, A
dc.contributor.authorInitials Musallam, KM
dc.contributor.authorInitials El Rassi, F
dc.contributor.authorInitials Duca, L
dc.contributor.authorInitials Inati, A
dc.contributor.authorInitials Koussa, S
dc.contributor.authorInitials Cappellini, MD
dc.contributor.authorReprintAddress Taher, A (reprint author), Amer Univ Beirut, Med Ctr, Dept Internal Med, Haematol Oncol Div, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 31
dc.description.citedTotWOSCount 33
dc.description.citedWOSCount 32
dc.format.extentCount 4
dc.identifier.coden BJHEA
dc.identifier.pubmedID 19604239
dc.identifier.scopusID 68949212139
dc.publisher.address COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA
dc.relation.ispartOfISOAbbr Br. J. Haematol.
dc.relation.ispartOfIssue 5
dc.relation.ispartofPubTitle British Journal of Haematology
dc.relation.ispartofPubTitleAbbr Br. J. Haematol.
dc.relation.ispartOfVolume 146
dc.source.ID WOS:000268923700011
dc.type.publication Journal
dc.subject.otherAuthKeyword Iron overload
dc.subject.otherAuthKeyword Non-transferrin-bound iron
dc.subject.otherAuthKeyword Thalassaemia intermedia
dc.subject.otherChemCAS ferritin, 9007-73-2
dc.subject.otherChemCAS transferrin, 82030-93-1
dc.subject.otherChemCAS Biological Markers
dc.subject.otherChemCAS Ferritins, 9007-73-2
dc.subject.otherChemCAS Iron, 7439-89-6
dc.subject.otherIndex ferritin
dc.subject.otherIndex iron binding protein
dc.subject.otherIndex non transferrin bound iron
dc.subject.otherIndex transferrin
dc.subject.otherIndex unclassified drug
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex child
dc.subject.otherIndex female
dc.subject.otherIndex ferritin blood level
dc.subject.otherIndex human
dc.subject.otherIndex iron overload
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex priority journal
dc.subject.otherIndex reference value
dc.subject.otherIndex school child
dc.subject.otherIndex splenectomy
dc.subject.otherIndex thalassemia
dc.subject.otherIndex thalassemia intermedia
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Biological Markers
dc.subject.otherIndex Child
dc.subject.otherIndex Cross-Sectional Studies
dc.subject.otherIndex Female
dc.subject.otherIndex Ferritins
dc.subject.otherIndex Humans
dc.subject.otherIndex Iron
dc.subject.otherIndex Iron Overload
dc.subject.otherIndex Liver
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Multivariate Analysis
dc.subject.otherIndex Splenectomy
dc.subject.otherIndex Thalassemia
dc.subject.otherIndex Young Adult
dc.subject.otherKeywordPlus BETA-THALASSEMIA
dc.subject.otherKeywordPlus SERUM FERRITIN
dc.subject.otherKeywordPlus PLASMA IRON
dc.subject.otherKeywordPlus LIVER
dc.subject.otherKeywordPlus THERAPY
dc.subject.otherWOS Hematology

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