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Malignancy and hypercoagulability: A two-way association revisited

Show simple item record Aoun E.G. Musallam K.M. Abou-Ghazal M. Taher A.T.
dc.contributor.editor Oct-2010 2017-10-05T15:37:53Z 2017-10-05T15:37:53Z 2010
dc.identifier 10.1007/s11239-010-0458-4
dc.identifier.issn 09295305
dc.description.abstract Increasing evidence is highlighting the relationship between malignancy and hypercoagulability as a bidirectional association. We herein share our experience with a patient in whom such an association may be entertained. The patient, who had a history of venous thromboembolism, presented to our care with manifestation of stroke. Extensive workup revealed that the patient carries prothrombotic mutations in the prothrombin and methylenetetrahydrofolate reductase genes. The patient, a non-smoker, was also diagnosed with non-small cell lung carcinoma. The possible association between the patient's malignancy and prothrombotic state are further discussed. © 2010 Springer Science+Business Media, LLC.
dc.format.extent Pages: (340-341)
dc.language English
dc.publisher DORDRECHT
dc.relation.ispartof Publication Name: Journal of Thrombosis and Thrombolysis; Publication Year: 2010; Volume: 30; no. 3; Pages: (340-341);
dc.source Scopus
dc.title Malignancy and hypercoagulability: A two-way association revisited
dc.type Short Survey
dc.contributor.affiliation Aoun, E.G., Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut Medical Center, Riad El Solh 1107 2020, Beirut, Lebanon
dc.contributor.affiliation Musallam, K.M., Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut Medical Center, Riad El Solh 1107 2020, Beirut, Lebanon
dc.contributor.affiliation Abou-Ghazal, M., Department of Neurosurgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, United States
dc.contributor.affiliation Taher, A.T., Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut Medical Center, Riad El Solh 1107 2020, Beirut, Lebanon
dc.contributor.authorAddress Taher, A. T.; Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut Medical Center, Riad El Solh 1107 2020, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Hematology-Oncology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Hematology-Oncology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Aoun, EG
dc.contributor.authorInitials Musallam, KM
dc.contributor.authorInitials Abou-Ghazal, M
dc.contributor.authorInitials Taher, AT
dc.contributor.authorReprintAddress Taher, AT (reprint author), Amer Univ Beirut, Med Ctr, Dept Internal Med, Div Hematol and Oncol, POB 11-0236,Riad El Solh 1107 2020, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited AGNELLI G, 2005, HAEMATOLOGICA, V90, P155; Batistelli S, 2006, WORLD J GASTRORNTERO, V12, P4179; Decousus H, 2007, THROMB RES, V120, pS51, DOI 10.1016-S0049-3848(07)70130-5; Franchini M, 2006, CRIT REV CL LAB SCI, V43, P249, DOI 10.1080-10408360600552678; GRAUS F, 1985, MEDICINE, V64, P16; Hankey GJ, 2001, STROKE, V32, P1793; Kuderer NM, 2007, CANCER, V110, P1149, DOI 10.1002-cncr.22892; Rickles FR, 2003, CHEST, V124, p58S, DOI 10.1378-chest.124.3_suppl.58S; Smorenburg SM, 2001, PHARMACOL REV, V53, P93; Taccone Fabio Silvio, 2008, J Stroke Cerebrovasc Dis, V17, P169, DOI 10.1016-j.jstrokecerebrovasdis.2008.01.007; Vairaktaris E, 2005, ANTICANCER RES, V25, P2561
dc.description.citedCount 1
dc.description.citedTotWOSCount 2
dc.description.citedWOSCount 1
dc.format.extentCount 2
dc.identifier.coden JTTHF
dc.identifier.pubmedID 20174855
dc.identifier.scopusID 77957943549
dc.relation.ispartOfISOAbbr J. Thromb. Thrombolysis
dc.relation.ispartOfIssue 3
dc.relation.ispartofPubTitle Journal of Thrombosis and Thrombolysis
dc.relation.ispartofPubTitleAbbr J. Thromb. Trombolysis
dc.relation.ispartOfVolume 30
dc.source.ID WOS:000282215300011
dc.type.publication Journal
dc.subject.otherAuthKeyword Hypercoagulability
dc.subject.otherAuthKeyword Lung cancer
dc.subject.otherAuthKeyword Malignancy
dc.subject.otherAuthKeyword Stroke
dc.subject.otherAuthKeyword Thrombophilia
dc.subject.otherAuthKeyword Venous thromboembolism
dc.subject.otherChemCAS 5,10 methylenetetrahydrofolate reductase (FADH2), 9028-69-7
dc.subject.otherChemCAS antithrombin, 9000-94-6
dc.subject.otherChemCAS protein C, 60202-16-6
dc.subject.otherChemCAS prothrombin, 9001-26-7
dc.subject.otherChemCAS Methylenetetrahydrofolate Reductase (NADPH2),
dc.subject.otherChemCAS Prothrombin, 9001-26-7
dc.subject.otherIndex 5,10 methylenetetrahydrofolate reductase (FADH2)
dc.subject.otherIndex antithrombin
dc.subject.otherIndex blood clotting factor 5 Leiden
dc.subject.otherIndex cardiolipin antibody
dc.subject.otherIndex lupus anticoagulant
dc.subject.otherIndex protein C
dc.subject.otherIndex protein S
dc.subject.otherIndex prothrombin
dc.subject.otherIndex adult
dc.subject.otherIndex case report
dc.subject.otherIndex cerebral artery disease
dc.subject.otherIndex cerebrovascular accident
dc.subject.otherIndex computer assisted tomography
dc.subject.otherIndex deep vein thrombosis
dc.subject.otherIndex dyslexia
dc.subject.otherIndex dysphasia
dc.subject.otherIndex female
dc.subject.otherIndex gene mutation
dc.subject.otherIndex human
dc.subject.otherIndex hypercoagulability
dc.subject.otherIndex lung embolism
dc.subject.otherIndex lung non small cell cancer
dc.subject.otherIndex magnetic resonance angiography
dc.subject.otherIndex muscle weakness
dc.subject.otherIndex nuclear magnetic resonance imaging
dc.subject.otherIndex priority journal
dc.subject.otherIndex short survey
dc.subject.otherIndex Adult
dc.subject.otherIndex Carcinoma, Non-Small-Cell Lung
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Methylenetetrahydrofolate Reductase (NADPH2)
dc.subject.otherIndex Mutation
dc.subject.otherIndex Neoplasms
dc.subject.otherIndex Prothrombin
dc.subject.otherIndex Stroke
dc.subject.otherIndex Thrombophilia
dc.subject.otherIndex Venous Thromboembolism
dc.subject.otherKeywordPlus INHERITED THROMBOPHILIA
dc.subject.otherKeywordPlus CANCER
dc.subject.otherKeywordPlus COMPLICATIONS
dc.subject.otherKeywordPlus RISK
dc.subject.otherWOS Hematology
dc.subject.otherWOS Peripheral Vascular Disease

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