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Redefining thalassemia as a hypercoagulable state

Show simple item record Cappellini M.D. Motta I. Musallam K.M. Taher A.T.
dc.contributor.editor Vichinsky E.P.Neufeld E.J. Aug-2010 2017-10-05T15:37:53Z 2017-10-05T15:37:53Z 2010
dc.identifier 10.1111/j.1749-6632.2010.05548.x
dc.identifier.isbn 9.7815733178e+012
dc.identifier.issn 00778923
dc.description.abstract As the life expectancy of β-thalassemia patients has markedly improved over the last decade, several new complications are being recognized. The presence of a high incidence of thromboembolic events, mainly in thalassemia intermedia patients, has led to the identification of a hypercoagulable state in thalassemia. In this review, the molecular and cellular mechanisms leading to hypercoagulability in thalassemia are highlighted, and the current clinical experience is summarized. Recommendations for thrombosis prophylaxis are also discussed. © 2010 New York Academy of Sciences.
dc.format.extent Pages: (231-236)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Annals of the New York Academy of Sciences; Publication Year: 2010; Volume: 1202; Pages: (231-236);
dc.source Scopus
dc.title Redefining thalassemia as a hypercoagulable state
dc.type Conference Paper
dc.contributor.affiliation Cappellini, M.D., Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy
dc.contributor.affiliation Motta, I., Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy
dc.contributor.affiliation Musallam, K.M., Hematology-Oncology Division, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Taher, A.T., Hematology-Oncology Division, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Cappellini, M. D.; Universitá di Milano, Fondazione Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena IRCCS, Milan, Italy; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Hematology-Oncology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Hematology-Oncology
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Cappellini, MD
dc.contributor.authorInitials Motta, I
dc.contributor.authorInitials Musallam, KM
dc.contributor.authorInitials Taher, AT
dc.contributor.authorReprintAddress Cappellini, MD (reprint author), Univ Milan, Fdn Osped Maggiore Policlin Mangiagalli Regina El, Milan, Italy.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 31
dc.description.citedTotWOSCount 29
dc.description.citedWOSCount 29
dc.format.extentCount 6
dc.identifier.coden ANYAA
dc.identifier.pubmedID 20712798
dc.identifier.scopusID 77955894491
dc.publisher.address 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXEN, ENGLAND
dc.relation.ispartofConferenceHosting New York Acad Sci
dc.relation.ispartOfISOAbbr Ann.NY Acad.Sci.
dc.relation.ispartofPubTitle Annals of the New York Academy of Sciences
dc.relation.ispartofPubTitleAbbr Ann. New York Acad. Sci.
dc.relation.ispartOfVolume 1202
dc.source.ID WOS:000283099600035
dc.type.publication Series
dc.subject.otherAuthKeyword hypercoagulability
dc.subject.otherAuthKeyword stroke
dc.subject.otherAuthKeyword thalassemia
dc.subject.otherAuthKeyword thromboembolism
dc.subject.otherChemCAS 5 aza 2' deoxycytidine, 2353-33-5
dc.subject.otherChemCAS endothelial leukocyte adhesion molecule 1, 128875-25-2
dc.subject.otherChemCAS hemoglobin F, 9034-63-3
dc.subject.otherChemCAS hydroxyurea, 127-07-1
dc.subject.otherChemCAS intercellular adhesion molecule 1, 126547-89-5
dc.subject.otherChemCAS nitric oxide, 10102-43-9
dc.subject.otherChemCAS prostacyclin, 35121-78-9, 61849-14-7
dc.subject.otherChemCAS spectrin, 12634-43-4
dc.subject.otherChemCAS thromboxane A2, 57576-52-0
dc.subject.otherChemCAS von Willebrand factor, 109319-16-6
dc.subject.otherIndex 5 aza 2' deoxycytidine
dc.subject.otherIndex ankyrin
dc.subject.otherIndex CD63 antigen
dc.subject.otherIndex endothelial leukocyte adhesion molecule 1
dc.subject.otherIndex erythrocyte band 3 protein
dc.subject.otherIndex hemoglobin F
dc.subject.otherIndex hydroxyurea
dc.subject.otherIndex intercellular adhesion molecule 1
dc.subject.otherIndex nitric oxide
dc.subject.otherIndex PADGEM protein
dc.subject.otherIndex prostacyclin
dc.subject.otherIndex spectrin
dc.subject.otherIndex thromboxane A2
dc.subject.otherIndex vascular cell adhesion molecule 1
dc.subject.otherIndex von Willebrand factor
dc.subject.otherIndex beta thalassemia
dc.subject.otherIndex blood transfusion
dc.subject.otherIndex conference paper
dc.subject.otherIndex erythrocyte
dc.subject.otherIndex follow up
dc.subject.otherIndex hemolysis
dc.subject.otherIndex human
dc.subject.otherIndex hypercoagulability
dc.subject.otherIndex sickle cell anemia
dc.subject.otherIndex splenectomy
dc.subject.otherIndex thrombocyte
dc.subject.otherIndex thrombocyte activation
dc.subject.otherIndex thrombocyte aggregation
dc.subject.otherIndex thrombocyte lifespan
dc.subject.otherIndex thromboembolism
dc.subject.otherIndex thrombosis
dc.subject.otherIndex urinary excretion
dc.subject.otherIndex Erythrocytes
dc.subject.otherIndex Humans
dc.subject.otherIndex Splenectomy
dc.subject.otherIndex Thalassemia
dc.subject.otherIndex Thrombophilia
dc.subject.otherKeywordPlus VIVO PLATELET ACTIVATION
dc.subject.otherKeywordPlus RED-BLOOD-CELLS
dc.subject.otherKeywordPlus BETA-THALASSEMIA
dc.subject.otherKeywordPlus THROMBOEMBOLIC EVENTS
dc.subject.otherKeywordPlus INTERMEDIA PATIENTS
dc.subject.otherKeywordPlus ENDOTHELIAL-CELLS
dc.subject.otherKeywordPlus MAJOR PATIENTS
dc.subject.otherKeywordPlus COMPLICATIONS
dc.subject.otherKeywordPlus ERYTHROCYTES
dc.subject.otherKeywordPlus SURVIVAL
dc.subject.otherWOS Hematology
dc.subject.otherWOS Multidisciplinary Sciences

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