AUB ScholarWorks

Interpretation and use of FRAX in clinical practice

Show simple item record

dc.contributor.author Kanis J.A.
dc.contributor.author Hans D.
dc.contributor.author Cooper C.
dc.contributor.author Baim S.
dc.contributor.author Bilezikian J.P.
dc.contributor.author Binkley N.
dc.contributor.author Cauley J.A.
dc.contributor.author Compston J.E.
dc.contributor.author Dawson-Hughes B.
dc.contributor.author El-Hajj Fuleihan G.
dc.contributor.author Johansson H.
dc.contributor.author Leslie W.D.
dc.contributor.author Lewiecki E.M.
dc.contributor.author Luckey M.
dc.contributor.author Oden A.
dc.contributor.author Papapoulos S.E.
dc.contributor.author Poiana C.
dc.contributor.author Rizzoli R.
dc.contributor.author Wahl D.A.
dc.contributor.author McClo
dc.contributor.editor
dc.date Sep-2011
dc.date.accessioned 2017-10-05T15:37:57Z
dc.date.available 2017-10-05T15:37:57Z
dc.date.issued 2011
dc.identifier 10.1007/s00198-011-1713-z
dc.identifier.isbn
dc.identifier.issn
dc.identifier.uri http://hdl.handle.net/10938/16048
dc.description.abstract Summary: The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but also limitations of which the clinician should be aware and are the focus of this review Introduction: The International Osteoporosis Foundation (IOF) and the International Society for Clinical Densitometry (ISCD) appointed a joint Task Force to develop resource documents in order to make recommendations on how to improve FRAX and better inform clinicians who use FRAX. The Task Force met in November 2010 for 3 days to discuss these topics which form the focus of this review. Methods: This study reviews the resource documents and joint position statements of ISCD and IOF. Results: Details on the clinical risk factors currently used in FRAX are provided, and the reasons for the exclusion of others are provided. Recommendations are made for the development of surrogate models where country-specific FRAX models are not available. Conclusions: The wish list of clinicians for the modulation of FRAX is large, but in many instances, these wishes cannot presently be fulfilled; however, an explanation and understanding of the reasons may be helpful in translating the information provided by FRAX into clinical practice. © 2011 International Osteoporosis Foundation and National Osteoporosis Foundation.
dc.format.extent
dc.format.extent Pages: (2395-2411)
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: Osteoporosis International; Publication Year: 2011; Volume: 22; no. 9; Pages: (2395-2411);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Interpretation and use of FRAX in clinical practice
dc.type Article
dc.contributor.affiliation Kanis, J.A., WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, United Kingdom
dc.contributor.affiliation Hans, D., Center of Bone Diseases, Bone and Joint Department, Lausanne University Hospital, Lausanne, Switzerland
dc.contributor.affiliation Cooper, C., MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, NIHR Musculoskeletal Biomedical Research Unit, Institute of Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
dc.contributor.affiliation Baim, S., Division of Endocrinology, University of Miami, Miller School of Medicine, Coral Gables, FL, United States
dc.contributor.affiliation Bilezikian, J.P., Columbia University, College of Physicians and Surgeons, New York, NY, United States
dc.contributor.affiliation Binkley, N., Osteoporosis Clinical Research Program, University of Wisconsin, Madison, WI, United States
dc.contributor.affiliation Cauley, J.A., Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, CA, United States
dc.contributor.affiliation Compston, J.E., Department of Medicine, Addenbrooke's Hospital, Cambridge University, Cambridge, United Kingdom
dc.contributor.affiliation Dawson-Hughes, B., Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States
dc.contributor.affiliation El-Hajj Fuleihan, G., WHO Collaborating Center for Metabolic Bone Disorders, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Johansson, H., Centre for Bone Research at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
dc.contributor.affiliation Leslie, W.D., University of Manitoba, Winnipeg, MB, Canada
dc.contributor.affiliation Lewiecki, E.M., New Mexico Clinical Research and Osteoporosis Center, University of New Mexico, School of Medicine, Albuquerque, NM, United States
dc.contributor.affiliation Luckey, M., St. Barnabas Osteoporosis and Metabolic Bone Disease Center, Livingston, NJ, United States
dc.contributor.affiliation Oden, A., Centre for Bone Research at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
dc.contributor.affiliation Papapoulos, S.E., Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, Netherlands
dc.contributor.affiliation Poiana, C., Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
dc.contributor.affiliation Rizzoli, R., Department of Rehabilitation and Geriatrics, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland
dc.contributor.affiliation Wahl, D.A., International Osteoporosis Foundation, Nyon, Switzerland
dc.contributor.affiliation McCloskey, E.V., Academic Unit of Bone Metabolism, University of Sheffield, Sheffield, United Kingdom
dc.contributor.authorAddress Kanis, J.A.; WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, United Kingdom; email: w.j.pontefract@sheffield.ac.uk
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail w.j.pontefract@sheffield.ac.uk
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Kanis, JA
dc.contributor.authorInitials Hans, D
dc.contributor.authorInitials Cooper, C
dc.contributor.authorInitials Baim, S
dc.contributor.authorInitials Bilezikian, JP
dc.contributor.authorInitials Binkley, N
dc.contributor.authorInitials Cauley, JA
dc.contributor.authorInitials Compston, JE
dc.contributor.authorInitials Dawson-Hughes, B
dc.contributor.authorInitials Fuleihan, GE
dc.contributor.authorInitials Johansson, H
dc.contributor.authorInitials Leslie, WD
dc.contributor.authorInitials Lewiecki, EM
dc.contributor.authorInitials Luckey, M
dc.contributor.authorInitials Oden, A
dc.contributor.authorInitials Papapoulos, SE
dc.contributor.authorInitials Poiana, C
dc.contributor.authorInitials Rizzoli, R
dc.contributor.authorInitials Wahl, DA
dc.contributor.authorInitials McCloskey, EV
dc.contributor.authorOrcidID Moayyeri, Alireza-0000-0002-9143-2161
dc.contributor.authorReprintAddress Kanis, JA (reprint author), Univ Sheffield, Sch Med, WHO Collaborating Ctr Metab Bone Dis, Beech Hill Rd, Sheffield S10 2RX, S Yorkshire, England.
dc.contributor.authorResearcherID Moayyeri, Alireza-N-3332-2014
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited ADAMS J, 2010, CAN QUS CALCANEUS BE; Etminan M, 2008, DRUG SAFETY, V31, P409, DOI 10.2165-00002018-200831050-00005; *ASS SUISS OST, 2011, OST REC 2010; Baim S, 2008, J CLIN DENSITOM, V11, P75, DOI 10.1016-j.jocd.2007.12.007; BARON JA, 1994, EPIDEMIOLOGY, V5, P42, DOI 10.1097-00001648-199401000-00008; Berg KM, 2008, AM J MED, V121, P406, DOI 10.1016-j.amjmed.2007.12.012; Bergmann P, 2009, INT J CLIN PRACT, V63, P19, DOI 10.1111-j.1742-1241.2008.01911.x; Bischoff-Ferrari HA, 2009, BRIT MED J, V339, DOI 10.1136-bmj.b3692; Black DM, 1999, J BONE MINER RES, V14, P821, DOI 10.1359-jbmr.1999.14.5.821; Blake GM, 2003, J BONE MINER RES, V18, P1955, DOI 10.1359-jbmr.2003.18.11.1955; BLANK R, 2011, J CLIN DENS IN PRESS; BOW CH, 2011, OSTEOPOROS IN PRESS; Brown JP, 2009, CLIN BIOCHEM, V42, P929, DOI 10.1016-j.clinbiochem.2009.04.001; BROY B, 2011, J CLIN DENS IN PRESS; Bulajic-Kopjar Marija, 1998, Tidsskrift for den Norske Laegeforening, V118, P30; Cameron I. D., 2010, COCHRANE DB SYST REV, V1, DOI [005410.001002-14651858.CD14005465.pub14651852, DOI 10.1002-14651858.CD00565.PUB2]; CAULEY JA, 2011, J CIN DENSI IN PRESS; Chang JT, 2004, BRIT MED J, V328, P680, DOI 10.1136-bmj.328.7441.680; Chevalley T, 2002, OSTEOPOROSIS INT, V13, P113, DOI 10.1007-s001980200002; Compston J, 2009, MATURITAS, V62, P105, DOI 10.1016-j.maturitas.2008.11.022; Confavreux CB, 2011, OSTEOPOROSIS INT, V22, P1023, DOI 10.1007-s00198-010-1462-4; Cooper C, 2011, OSTEOPOROSIS INT, V22, P1277, DOI 10.1007-s00198-011-1601-6; CUMMINGS SR, 1995, NEW ENGL J MED, V332, P767, DOI 10.1056-NEJM199503233321202; Czerwinski E, 2009, OSTEOPOROSIS INT, V20, P1363, DOI 10.1007-s00198-008-0787-8; Dam TT, 2010, OSTEOPOROSIS INT, V21, P1341, DOI 10.1007-s00198-009-1076-x; Dawson-Hughes B, 2008, J CLIN ENDOCR METAB, V93, P2463, DOI 10.1210-jc.2008-0926; De Laet C, 2005, OSTEOPOROSIS INT, V16, P313, DOI 10.1007-s00198-004-1689-z; Delmas PD, 2003, BONE, V33, P522, DOI 10.1016-S8756-3282(03)00241-2; DIMAI HP, 2011, J CLIN DENS IN PRESS; ELFFORS I, 1994, OSTEOPOROSIS INT, V4, P253, DOI 10.1007-BF01623349; Faulkner KG, 1999, J CLIN DENSITOM, V2, P343, DOI 10.1385-JCD:2:3:343; FINSEN V, 1987, CLIN ORTHOP RELAT R, P104; Fox KM, 1998, OSTEOPOROSIS INT, V8, P557, DOI 10.1007-s001980050099; Fujiwara S, 2008, OSTEOPOROSIS INT, V19, P429, DOI 10.1007-s00198-007-0544-4; Fukunaga M, 2006, JAPANESE GUIDELINES; Gillespie LD, 2009, COCHRANE DB SYST REV, DOI 10.1002-14651858.CD007146.pub2; Grossman JM, 2010, ARTHRIT CARE RES, V62, P1515, DOI 10.1002-acr.20295; Gullberg B, 1997, OSTEOPOROSIS INT, V7, P407, DOI 10.1007-PL00004148; Hans D, 2008, J BONE MINER RES, V23, P1045, DOI [10.1359-jbmr.080229, 10.1359-JBMR.080229]; HANS D, 2011, J CLIN DENS IN PRESS; Hippisley-Cox J, 2009, BRIT MED J, V339, DOI 10.1136-bmj.b4229; JACOBSEN SJ, 1990, JAMA-J AM MED ASSOC, V264, P500, DOI 10.1001-jama.264.4.500; Johansson H, 2011, OSTEOPOROSIS INT, V22, P453, DOI 10.1007-s00198-010-1218-1; Johnell O, 1997, OSTEOPOROSIS INT, V7, P138, DOI 10.1007-BF01623689; Johnell O, 2005, J BONE MINER RES, V20, P1185, DOI 10.1359-JBMR.050304; JONSSON B, 1992, OSTEOPOROSIS INT, V2, P269, DOI 10.1007-BF01623181; Kaastad TS, 1998, BONE, V22, P175, DOI 10.1016-S8756-3282(97)00247-0; Kanis J, 2010, ARCH OSTEOPOROS, DOI [10.1007-s11657-010-0045-5, DOI 10.1007-S11657-010-0045-5]; Kanis JA, 2008, OSTEOPOROSIS INT, V19, P1395, DOI 10.1007-s00198-008-0712-1; Kanis JA, 2008, ASSESSMENT OSTEOPORO; Kanis JA, 2005, OSTEOPOROSIS INT, V16, P155, DOI 10.1007-s00198-004-1640-3; Kanis JA, 2008, BONE, V42, P467, DOI 10.1016-j.bone.2007.11.001; Kanis JA, 2009, BONE, V44, P734, DOI 10.1016-j.bone.2009.01.373; Kanis JA, 2006, OSTEOPOROSIS INT, V17, P527, DOI 10.1007-s00198-005-0014-9; Kanis JA, 2010, OSTEOPOROSIS INT, V21, P35, DOI 10.1007-s00198-009-1033-8; Kanis JA, 2004, BONE, V35, P1029, DOI 10.1016-j.bone.2004.06.017; Kanis JA, 2008, OSTEOPOROSIS INT, V19, P385, DOI 10.1007-s00198-007-0543-5; Kanis JA, 2001, OSTEOPOROSIS INT, V12, P417, DOI 10.1007-s001980170112; Kanis JA, 2007, OSTEOPOROSIS INT, V18, P1033, DOI 10.1007-s00198-007-0343-y; KANIS JA, 2010, OSTEOPOROSIS INT, V22, P809; Kanis JA, 2002, BONE, V30, P251, DOI 10.1016-S8756-3282(01)00653-6; Kanis JA, 2004, J BONE MINER RES, V19, P893, DOI 10.1359-JBMR.040134; Kanis JA, 2005, OSTEOPOROSIS INT, V16, P737, DOI 10.1007-s00198-004-1734-y; Kanis JA, 2008, OSTEOPOROSIS INT, V19, P399, DOI 10.1007-s00198-008-0560-z; Kayan K, 2009, OSTEOPOROSIS INT, V20, P2055, DOI 10.1007-s00198-009-0942-x; Kjensli A, 2009, EUR RESPIR J, V33, P1018, DOI 10.1183-09031936.00073908; Lakatos P, 2011, ARCH OSTEOPOROS, DOI [10.1007-s11657-010-0048-2, DOI 10.1007-S11657-010-0048-2]; Lauderdale DS, 1998, AM J PUBLIC HEALTH, V88, P1245, DOI 10.2105-AJPH.88.8.1245; Law MR, 1997, BRIT MED J, V315, P841; LEIB ES, 2011, J CLIN DENS IN PRESS; LESLIE WD, 2010, J BONE MINER RES S1, V25, pS60; Leslie WD, 2011, OSTEOPOROSIS INT, V22, P839, DOI 10.1007-s00198-010-1461-5; Leslie WD, 2007, J BONE MINER RES, V22, P476, DOI 10.1359-JBMR.061112; LEVINE S, 1970, Journal of Bone and Joint Surgery American Volume, V52, P1193; LEWIECKI EM, 2011, J CLIN DENS IN PRESS; Lippuner K, 2010, OSTEOPOROSIS INT, V21, P381, DOI 10.1007-s00198-009-0975-1; Lippuner K, 1997, OSTEOPOROSIS INT, V7, P414, DOI 10.1007-PL00004149; Looker AC, 1998, OSTEOPOROSIS INT, V8, P468, DOI 10.1007-s001980050093; Lunt M, 2003, BONE, V33, P505, DOI 10.1016-S8756-3282(03)00248-5; MADHOK R, 1993, ACTA ORTHOP SCAND, V64, P543, DOI 10.3109-17453679308993689; Marshall D, 1996, BRIT MED J, V312, P1254; MASUD T, 2011, J CLIN DENS IN PRESS; MATKOVIC V, 1979, AM J CLIN NUTR, V32, P540; McCloskey EV, 2007, J BONE MINER RES, V22, P135, DOI 10.1359-JBMR.061008; McClung MR, 2001, NEW ENGL J MED, V344, P333, DOI 10.1056-NEJM200102013440503; Melton III LJ, 1995, OSTEOPOROSIS ETIOLOG, P225; Melton LJ, 1999, OSTEOPOROSIS INT, V9, P29, DOI 10.1007-s001980050113; National Osteoporosis Foundation, 2008, CLIN GUID PREV TREAT; Neuprez A, 2009, Rev Med Liege, V64, P612; Nguyen ND, 2008, OSTEOPOROSIS INT, V19, P1431, DOI 10.1007-s00198-008-0588-0; Office of the Surgeon General (US), 2004, BON HLTH OST REP SUR; Oliver D, 1997, BRIT MED J, V315, P1049; Papaioannou A, 2010, CAN MED ASSOC J, V182, P1864, DOI 10.1503-cmaj.100771; Puisto V, 2011, OSTEOPOROSIS INT, V22, P63, DOI 10.1007-s00198-010-1195-4; Sanders KM, 1998, J BONE MINER RES, V13, P1337, DOI 10.1359-jbmr.1998.13.8.1337; Singer BR, 1998, J BONE JOINT SURG BR, V80B, P234; Siris ES, 2007, OSTEOPOROSIS INT, V18, P761, DOI 10.1007-s00198-006-0306-8; Socialstyrelsen, 2010, NAT RIKTL ROR SJUKD; Stone KL, 2003, J BONE MINER RES, V18, P1947, DOI 10.1359-jbmr.2003.18.11.1947; Szulc P, 2008, OSTEOPOROSIS INT, V19, P1683, DOI 10.1007-s00198-008-0660-9; Toyabe S, 2010, BMC HEALTH SERV RES, V10, DOI 10.1186-1472-6963-10-106; Calonge N, 2011, ANN INTERN MED, V154, P356, DOI 10.1059-0003-4819-154-5-201103010-00307; van Staa TP, 2001, BRIT J CLIN PHARMACO, V51, P601, DOI 10.1046-j.0306-5251.2001.bjcp.1385.x; Van Staa TP, 2000, J BONE MINER RES, V15, P993, DOI 10.1359-jbmr.2000.15.6.993; van Staa TP, 2000, RHEUMATOLOGY, V39, P1383, DOI 10.1093-rheumatology-39.12.1383; van Staa TP, 2001, J BONE MINER RES, V16, P581, DOI 10.1359-jbmr.2001.16.3.581; Vasikaran S, 2011, OSTEOPOROSIS INT, V22, P391, DOI 10.1007-s00198-010-1501-1; Vasikaran SD, 2008, CRIT REV CL LAB SCI, V45, P221, DOI 10.1080-10408360801949442 ; VESTERGAARD P, 2010, ALCOHOL ISCD IOF FRA; Vestergaard P, 2003, J INTERN MED, V254, P572, DOI 10.1111-j.1365-2796.2003.01232.x; Wittich A, 2010, OSTEOPOROSIS INT, V21, P1803, DOI 10.1007-s00198-009-1135-3; World Health Organization, 2007, ASS OST PRIM HLTH CA; Zingmond DS, 2004, OSTEOPOROSIS INT, V15, P603, DOI 10.1007-s00198-004-1592-7
dc.description.citedCount 109
dc.description.citedTotWOSCount 91
dc.description.citedWOSCount 84
dc.format.extentCount 17
dc.identifier.articleNo
dc.identifier.coden OSINE
dc.identifier.pubmedID 21779818
dc.identifier.scopusID 80052313108
dc.identifier.url
dc.publisher.address 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Osteoporosis Int.
dc.relation.ispartOfIssue 9
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Osteoporosis International
dc.relation.ispartofPubTitleAbbr Osteoporosis Int.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 22
dc.source.ID WOS:000293636500001
dc.type.publication Journal
dc.subject.otherAuthKeyword Bone mineral density
dc.subject.otherAuthKeyword Clinical risk factors
dc.subject.otherAuthKeyword Fracture probability
dc.subject.otherAuthKeyword Risk assessment
dc.subject.otherChemCAS alcohol, 64-17-5
dc.subject.otherChemCAS beclometasone, 4419-39-0
dc.subject.otherChemCAS prednisolone, 50-24-8
dc.subject.otherIndex alcohol
dc.subject.otherIndex beclometasone
dc.subject.otherIndex prednisolone
dc.subject.otherIndex algorithm
dc.subject.otherIndex article
dc.subject.otherIndex bone density
dc.subject.otherIndex bone turnover
dc.subject.otherIndex calculation
dc.subject.otherIndex clinical practice
dc.subject.otherIndex computer program
dc.subject.otherIndex drug exposure
dc.subject.otherIndex evaluation
dc.subject.otherIndex falling
dc.subject.otherIndex female
dc.subject.otherIndex fracture
dc.subject.otherIndex human
dc.subject.otherIndex medical society
dc.subject.otherIndex prediction
dc.subject.otherIndex priority journal
dc.subject.otherIndex probability
dc.subject.otherIndex rheumatoid arthritis
dc.subject.otherIndex risk assessment
dc.subject.otherIndex risk factor
dc.subject.otherIndex secondary osteoporosis
dc.subject.otherIndex smoking
dc.subject.otherIndex Algorithms
dc.subject.otherIndex Bone Density
dc.subject.otherIndex Female
dc.subject.otherIndex Fractures, Bone
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Models, Statistical
dc.subject.otherIndex Osteoporosis
dc.subject.otherIndex Practice Guidelines as Topic
dc.subject.otherIndex Risk Assessment
dc.subject.otherIndex Risk Factors
dc.subject.otherIndex World Health
dc.subject.otherIndex World Health Organization
dc.subject.otherKeywordPlus FRACTURE RISK-ASSESSMENT
dc.subject.otherKeywordPlus BONE-MINERAL DENSITY
dc.subject.otherKeywordPlus HIP FRACTURE
dc.subject.otherKeywordPlus OSTEOPOROTIC FRACTURES
dc.subject.otherKeywordPlus ORAL CORTICOSTEROIDS
dc.subject.otherKeywordPlus BIOCHEMICAL MARKERS
dc.subject.otherKeywordPlus VERTEBRAL FRACTURE
dc.subject.otherKeywordPlus ASSESSMENT-TOOL
dc.subject.otherKeywordPlus ELDERLY-WOMEN
dc.subject.otherKeywordPlus POSTMENOPAUSAL OSTEOPOROSIS
dc.subject.otherWOS Endocrinology and Metabolism


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search AUB ScholarWorks


Browse

My Account