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Comparison of late coronary artery bypass graft survival effects of radial artery versus saphenous vein grafting in male and female patients

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dc.contributor.author Schwann T.A.
dc.contributor.author Engoren M.
dc.contributor.author Bonnell M.
dc.contributor.author Clancy C.
dc.contributor.author Habib R.H.
dc.contributor.editor
dc.date Nov-2012
dc.date.accessioned 2017-10-05T15:38:10Z
dc.date.available 2017-10-05T15:38:10Z
dc.date.issued 2012
dc.identifier 10.1016/j.athoracsur.2012.05.029
dc.identifier.isbn
dc.identifier.issn 00034975
dc.identifier.uri http://hdl.handle.net/10938/16169
dc.description.abstract Background: This study aimed to compare the survival benefit derived from using radial artery (RA) as a second arterial conduit in combination with internal thoracic artery (ITA), as opposed to ITA plus saphenous vein (SV) in men and women. Methods: We reviewed the 1996 to 2007 primary, nonsalvage coronary artery bypass graft surgery (CABG) experience at Mercy Saint Vincent Medical Center (n = 6,384; 69percent men, 31percent women). Study subjects had two or more completed grafts including one ITA graft. Patients with bilateral ITA, ITA-only grafts, or concomitant valve-aortic surgery were excluded. Separate sex nonparsimonious propensity models for RA grafting based on 47 preoperative and intraoperative factors were used to identify matched ITA-RA and ITA-SV cohorts. Kaplan-Meier and Cox regression analyses were then applied to assess sex-specific 12-year survival risk ratios of RA versus SV grafting. Results: Patient variables for the RA and SV cohorts were well-matched in both men (n = 1,416 each; median age 62 years) and women (n = 567 each; median age 66 years). Thirty-day mortality was similar for ITA-RA versus ITA-SV in men (1.3percent versus 1.2percent; p = 1.0) and women (1.4percent versus 1.9percent; p = 0.664). Late mortality (1 to 144 months) was significantly better for ITA-RA in men (risk ratio 0.65, 95percent confidence interval: 0.54 to 0.79; p 0.001) and women (risk ratio 0.75, 95percent confidence interval: 0.57 to 0.99; p = 0.045). Conclusions: Late survival results suggest that male and female CABG patients benefit appreciably from use of RA as a second arterial conduit in combination with ITA. Yet, the late survival advantage derived from RA use was relatively less for women. This sex variance in benefit likely reflects differences in risk profiles of male and female CABG patients. © 2012 The Society of Thoracic Surgeons.
dc.format.extent
dc.format.extent Pages: (1485-1491)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Annals of Thoracic Surgery; Publication Year: 2012; Volume: 94; no. 5; Pages: (1485-1491);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Comparison of late coronary artery bypass graft survival effects of radial artery versus saphenous vein grafting in male and female patients
dc.type Article
dc.contributor.affiliation Schwann, T.A., Department of Surgery, University of Toledo College of Medicine, Toledo, OH, United States
dc.contributor.affiliation Engoren, M., Mercy Saint Vincent Medical Center, Toledo, OH, United States
dc.contributor.affiliation Bonnell, M., Department of Surgery, University of Toledo College of Medicine, Toledo, OH, United States
dc.contributor.affiliation Clancy, C., Department of Surgery, University of Toledo College of Medicine, Toledo, OH, United States
dc.contributor.affiliation Habib, R.H., Outcomes Research Unit, Department of Internal Medicine, American University of Beirut, Riad El-Solh 1107 2020, Beirut, Lebanon
dc.contributor.authorAddress Habib, R.H.; Outcomes Research Unit, Department of Internal Medicine, American University of Beirut, Riad El-Solh 1107 2020, Beirut, Lebanon; email: rh106@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail rh106@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Schwann, TA
dc.contributor.authorInitials Engoren, M
dc.contributor.authorInitials Bonnell, M
dc.contributor.authorInitials Clancy, C
dc.contributor.authorInitials Habib, RH
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Habib, RH (reprint author), Amer Univ Beirut, Med Ctr, Outcomes Res Unit, POB 11-0236,Riad El Solh 1107 2020, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 9
dc.description.citedTotWOSCount 10
dc.description.citedWOSCount 10
dc.format.extentCount 7
dc.identifier.articleNo
dc.identifier.coden ATHSA
dc.identifier.pubmedID 22771486
dc.identifier.scopusID 84867778091
dc.identifier.url
dc.publisher.address 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Ann. Thorac. Surg.
dc.relation.ispartOfIssue 5
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Annals of Thoracic Surgery
dc.relation.ispartofPubTitleAbbr Ann. Thorac. Surg.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 94
dc.source.ID WOS:000310439700026
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex article
dc.subject.otherIndex comparative effectiveness
dc.subject.otherIndex coronary artery bypass graft
dc.subject.otherIndex female
dc.subject.otherIndex graft survival
dc.subject.otherIndex human
dc.subject.otherIndex internal mammary artery
dc.subject.otherIndex intraoperative period
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex post treatment survival
dc.subject.otherIndex preoperative period
dc.subject.otherIndex priority journal
dc.subject.otherIndex radial artery
dc.subject.otherIndex retrospective study
dc.subject.otherIndex saphenous vein graft
dc.subject.otherIndex sex difference
dc.subject.otherIndex surgical mortality
dc.subject.otherIndex Aged
dc.subject.otherIndex Coronary Artery Bypass
dc.subject.otherIndex Coronary Artery Disease
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Radial Artery
dc.subject.otherIndex Retrospective Studies
dc.subject.otherIndex Saphenous Vein
dc.subject.otherIndex Sex Factors
dc.subject.otherIndex Survival Rate
dc.subject.otherKeywordPlus INTERNAL-MAMMARY-ARTERY
dc.subject.otherKeywordPlus FOLLOW-UP
dc.subject.otherKeywordPlus RANDOMIZED-TRIAL
dc.subject.otherKeywordPlus 10-YEAR SURVIVAL
dc.subject.otherKeywordPlus THORACIC ARTERY
dc.subject.otherKeywordPlus SURGERY
dc.subject.otherKeywordPlus PATENCY
dc.subject.otherKeywordPlus WOMEN
dc.subject.otherKeywordPlus CONDUITS
dc.subject.otherKeywordPlus MORTALITY
dc.subject.otherWOS Cardiac and Cardiovascular Systems
dc.subject.otherWOS Respiratory System
dc.subject.otherWOS Surgery


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