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The role of therapeutic plasma exchange in the catastrophic antiphospholipid syndrome

Show simple item record Uthman I. Shamseddine A. Taher A.
dc.contributor.editor Aug-2005 2017-10-05T15:38:18Z 2017-10-05T15:38:18Z 2005
dc.identifier 10.1016/j.transci.2004.10.025
dc.identifier.issn 14730502
dc.description.abstract The catastrophic antiphospholipid syndrome (CAPS) is a life-threatening sub-entity of the antiphospholipid syndrome (APS) resulting in multiorgan failure and a mortality rate that may reach 50percent. The optimal treatment regimen for CAPS is unknown. To evaluate the benefit of therapeutic plasma exchange (TPE) therapy in CAPS, we undertook a computer-assisted (MEDLINE, National Library of Medicine, Bethesda, MD) search of the literature to locate all cases of CAPS (case reports and reviews) treated with TPE. In view of the published literature so far, TPE has shown reasonable therapeutic benefits and improved survival for patients with CAPS. The use of this technique, along with anticoagulation and if needed pharmacological immunosuppression, should be considered for the acute management of patients who present with this life-threatening condition. © 2005 Elsevier Ltd. All rights reserved.
dc.format.extent Pages: (11-17)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Transfusion and Apheresis Science; Publication Year: 2005; Volume: 33; no. 1; Pages: (11-17);
dc.source Scopus
dc.title The role of therapeutic plasma exchange in the catastrophic antiphospholipid syndrome
dc.type Article
dc.contributor.affiliation Uthman, I., Department of Internal Medicine, Division of Rheumatology, American University of Beirut Medical Center (AUBMC), Hamra Street, Beirut 1107 2802, Lebanon
dc.contributor.affiliation Shamseddine, A., Department of Internal Medicine, Division of Hematology-Oncology, American University of Beirut Medical Center (AUBMC), Hamra Street, Beirut 1107 2802, Lebanon
dc.contributor.affiliation Taher, A., Department of Internal Medicine, Division of Hematology-Oncology, American University of Beirut Medical Center (AUBMC), Hamra Street, Beirut 1107 2802, Lebanon
dc.contributor.authorAddress Taher, A.; Department of Internal Medicine, Division of Hematology-Oncology, American University of Beirut Medical Center (AUBMC), Hamra Street, Beirut 1107 2802, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Rheumatology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Rheumatology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Uthman, I
dc.contributor.authorInitials Shamseddine, A
dc.contributor.authorInitials Taher, A
dc.contributor.authorReprintAddress Taher, A (reprint author), Amer Univ Beirut, Med Ctr, Div Hematol Oncol, Dept Internal Med, Hamra St, Beirut 1107 2802, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 32
dc.description.citedTotWOSCount 21
dc.description.citedWOSCount 21
dc.format.extentCount 7
dc.identifier.coden TASRC
dc.identifier.pubmedID 15951243
dc.identifier.scopusID 22144480903
dc.relation.ispartOfISOAbbr Transfus. Apher. Sci.
dc.relation.ispartOfIssue 1
dc.relation.ispartofPubTitle Transfusion and Apheresis Science
dc.relation.ispartofPubTitleAbbr Transfus. Apheresis Sci.
dc.relation.ispartOfVolume 33
dc.source.ID WOS:000231157800003
dc.type.publication Journal
dc.subject.otherAuthKeyword Catastrophic antiphospholipid syndrome
dc.subject.otherAuthKeyword Therapeutic plasma exchange
dc.subject.otherChemCAS cyclophosphamide, 50-18-0
dc.subject.otherChemCAS heparin, 37187-54-5, 8057-48-5, 8065-01-8, 9005-48-5
dc.subject.otherChemCAS immunoglobulin, 9007-83-4
dc.subject.otherChemCAS methylprednisolone, 6923-42-8, 83-43-2
dc.subject.otherChemCAS ticlopidine, 53885-35-1, 55142-85-3
dc.subject.otherIndex anticoagulant agent
dc.subject.otherIndex cyclophosphamide
dc.subject.otherIndex heparin
dc.subject.otherIndex immunoglobulin
dc.subject.otherIndex methylprednisolone
dc.subject.otherIndex steroid
dc.subject.otherIndex ticlopidine
dc.subject.otherIndex antiphospholipid syndrome
dc.subject.otherIndex article
dc.subject.otherIndex blood transfusion reaction
dc.subject.otherIndex chill
dc.subject.otherIndex clinical trial
dc.subject.otherIndex diaphoresis
dc.subject.otherIndex evaluation
dc.subject.otherIndex human
dc.subject.otherIndex immunosuppressive treatment
dc.subject.otherIndex medical literature
dc.subject.otherIndex MEDLINE
dc.subject.otherIndex nausea
dc.subject.otherIndex plasmapheresis
dc.subject.otherIndex respiratory distress
dc.subject.otherIndex rigor
dc.subject.otherIndex seizure
dc.subject.otherIndex survival
dc.subject.otherIndex tetany
dc.subject.otherIndex treatment outcome
dc.subject.otherIndex vomiting
dc.subject.otherIndex Antiphospholipid Syndrome
dc.subject.otherIndex Catastrophic Illness
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Plasma Exchange
dc.subject.otherKeywordPlus SYSTEMIC-LUPUS-ERYTHEMATOSUS
dc.subject.otherKeywordPlus ANTICARDIOLIPIN ANTIBODIES
dc.subject.otherKeywordPlus APHERESIS
dc.subject.otherKeywordPlus PLASMAPHERESIS
dc.subject.otherKeywordPlus ANTICOAGULATION
dc.subject.otherKeywordPlus PREGNANCY
dc.subject.otherKeywordPlus PATIENT
dc.subject.otherKeywordPlus IMMUNOSUPPRESSION
dc.subject.otherKeywordPlus PREDNISOLONE
dc.subject.otherWOS Hematology

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