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Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients

Show simple item record Abou-Mrad R.M. Abu-Alfa A.K. Ziyadeh F.N.
dc.contributor.editor Sep-2013 2017-10-05T15:38:21Z 2017-10-05T15:38:21Z 2013
dc.identifier 10.1152/ajprenal.00173.2013
dc.identifier.issn 03636127
dc.description.abstract Increasing evidence nowadays is showing that obesity by itself, independent of other comorbidities like diabetes and hypertension, is associated with renal functional changes and structural damage. Intentional weight loss demonstrates beneficial reduction in proteinuria and albuminuria in patients with mild to moderate chronic kidney disease, particularly those whose renal damage is likely induced by obesity. The safety of some weight loss interventions, particularly the use of high-protein diets and-or medications, is questionable in this population due to the lack of well-designed randomized controlled studies reporting on their efficacy or harm. Bariatric surgery showed the most promising results with regards to ameliorating glomerular hyperfiltration and albuminuria albeit with a modest risk of increased perioperative complications with advanced stages of chronic kidney disease (CKD). © 2013 by the American Physiological Society.
dc.language English
dc.publisher BETHESDA
dc.relation.ispartof Publication Name: American Journal of Physiology - Renal Physiology; Publication Year: 2013; Volume: 305; no. 5;
dc.source Scopus
dc.title Effects of weight reduction regimens and bariatric surgery on chronic kidney disease in obese patients
dc.type Article
dc.contributor.affiliation Abou-Mrad, R.M., Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Abu-Alfa, A.K., Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Ziyadeh, F.N., Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.authorAddress Ziyadeh, F. N.; Dept. of Internal Medicine, American Univ. of Beirut, P.O. Box: 11-0236, Riad El-Solh 1107 2020, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Abou-Mrad, RM
dc.contributor.authorInitials Abu-Alfa, AK
dc.contributor.authorInitials Ziyadeh, FN
dc.contributor.authorReprintAddress Ziyadeh, FN (reprint author), Amer Univ Beirut, Dept Internal Med, POB 11-0236, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 1
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.identifier.coden AJPPF
dc.identifier.pubmedID 23825072
dc.identifier.scopusID 84883389876
dc.publisher.address 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA
dc.relation.ispartOfISOAbbr Am. J. Physiol.-Renal Physiol.
dc.relation.ispartOfIssue 5
dc.relation.ispartofPubTitle American Journal of Physiology - Renal Physiology
dc.relation.ispartofPubTitleAbbr Am. J. Physiol. Renal Physiol.
dc.relation.ispartOfVolume 305
dc.source.ID WOS:000324101000001
dc.type.publication Journal
dc.subject.otherAuthKeyword Albuminuria
dc.subject.otherAuthKeyword Creatinine clearance
dc.subject.otherAuthKeyword Hyperfiltration
dc.subject.otherAuthKeyword Proteinuria
dc.subject.otherAuthKeyword Weight loss
dc.subject.otherChemCAS cyclosporin, 79217-60-0
dc.subject.otherChemCAS tetrahydrolipstatin, 96829-58-2
dc.subject.otherIndex cyclosporin
dc.subject.otherIndex tetrahydrolipstatin
dc.subject.otherIndex acute kidney failure
dc.subject.otherIndex albuminuria
dc.subject.otherIndex article
dc.subject.otherIndex bariatric surgery
dc.subject.otherIndex caloric restriction
dc.subject.otherIndex chronic kidney disease
dc.subject.otherIndex clinical effectiveness
dc.subject.otherIndex disease course
dc.subject.otherIndex disease severity
dc.subject.otherIndex drug safety
dc.subject.otherIndex glomerulus filtration rate
dc.subject.otherIndex human
dc.subject.otherIndex kidney function
dc.subject.otherIndex kinesiotherapy
dc.subject.otherIndex lifestyle modification
dc.subject.otherIndex meta analysis (topic)
dc.subject.otherIndex nonhuman
dc.subject.otherIndex obesity
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex pathophysiology
dc.subject.otherIndex patient safety
dc.subject.otherIndex peroperative complication
dc.subject.otherIndex physical activity
dc.subject.otherIndex priority journal
dc.subject.otherIndex protein diet
dc.subject.otherIndex proteinuria
dc.subject.otherIndex randomized controlled trial (topic)
dc.subject.otherIndex surgical risk
dc.subject.otherIndex systematic review (topic)
dc.subject.otherIndex therapy effect
dc.subject.otherIndex weight reduction
dc.subject.otherIndex albuminuria
dc.subject.otherIndex creatinine clearance
dc.subject.otherIndex hyperfiltration
dc.subject.otherIndex proteinuria
dc.subject.otherIndex weight loss
dc.subject.otherIndex Albuminuria
dc.subject.otherIndex Animals
dc.subject.otherIndex Bariatric Surgery
dc.subject.otherIndex Diet, Reducing
dc.subject.otherIndex Exercise
dc.subject.otherIndex Glomerular Filtration Rate
dc.subject.otherIndex Humans
dc.subject.otherIndex Obesity
dc.subject.otherIndex Proteinuria
dc.subject.otherIndex Renal Insufficiency, Chronic
dc.subject.otherIndex Weight Loss
dc.subject.otherKeywordPlus NORMAL RENAL-FUNCTION
dc.subject.otherKeywordPlus SPRAGUE-DAWLEY RATS
dc.subject.otherKeywordPlus PROTEIN
dc.subject.otherKeywordPlus LEPTIN
dc.subject.otherKeywordPlus RESTRICTION
dc.subject.otherKeywordPlus ALDOSTERONE
dc.subject.otherKeywordPlus MANAGEMENT
dc.subject.otherKeywordPlus IMPACT
dc.subject.otherKeywordPlus INJURY
dc.subject.otherKeywordPlus DIET
dc.subject.otherWOS Physiology
dc.subject.otherWOS Urology and Nephrology

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