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Clinical features of HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM-TSP) in northeast Iran

Show simple item record Shoeibi A. Rafatpanah H. Azarpazhooh A. Mokhber N. Hedayati-Moghaddam M.R. Amiri A. Hashemi P. Foroghipour M. Hoseini R.F. Bazarbachi A. Azarpazhooh M.R.
dc.contributor.editor Jan-2013 2017-10-05T15:38:23Z 2017-10-05T15:38:23Z 2013
dc.identifier 10.1007/s13760-013-0194-6
dc.identifier.issn 03009009
dc.description.abstract This study aimed to introduce clinical manifestations of patients in northeast Iran with HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM-TSP) and describe the epidemiological features, as well as risk factors for HTLV-1 infection. This is a cross-sectional study of HTLV-1 infected cases and HAM-TSP patients referred by outpatient neurology clinics as well as Mashhad Blood Transfusion Center from 2005 to 2010. The study comprises 513 cases, including 358 healthy carriers (HCs) and 145 HAM-TSP patients. The majority of carriers were male (73.5 percent), whereas 67.6 percent of HAM-TSP sufferers were female (P 0.001). The mean age of HAM-TSP patients and HCs was 45.9 ± 13.6 and 39.5 ± 11.58 years, respectively (P 0.001). The history of transfusion, surgery, hospitalization and cupping was observed in a significant greater number of HAM-TSP patients than the HCs (P 0.001, P 0.001, P 0.001 and P = 0.029, respectively). Gait disturbance was the most common complaint in HAM-TSP patients (72.4 percent). This research develops an HTLV-1 data registry in an endemic area such as Mashhad which can serve useful purposes, including evaluation of clinical and laboratory characteristics of HAM-TSP patients and epidemiological data of HTLV-1-infected cases. © 2013 Belgian Neurological Society.
dc.format.extent Pages: (427-433)
dc.language English
dc.relation.ispartof Publication Name: Acta Neurologica Belgica; Publication Year: 2013; Volume: 113; no. 4; Pages: (427-433);
dc.source Scopus
dc.title Clinical features of HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM-TSP) in northeast Iran
dc.type Article
dc.contributor.affiliation Shoeibi, A., Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran
dc.contributor.affiliation Rafatpanah, H., Inflammation and Inflammatory Diseases Research Centre, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
dc.contributor.affiliation Azarpazhooh, A., Community Dental Health Services Research Unit, University of Toronto, Toronto, ON, Canada
dc.contributor.affiliation Mokhber, N., Department of Neuropsychology, Ibn-e-Sina Hospital, Mashhad University of Medical Science, Mashhad, Iran
dc.contributor.affiliation Hedayati-Moghaddam, M.R., Research Center for HIV-AIDS, HTLV and Viral Hepatitis, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran
dc.contributor.affiliation Amiri, A., Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran
dc.contributor.affiliation Hashemi, P., Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran
dc.contributor.affiliation Foroghipour, M., Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran
dc.contributor.affiliation Hoseini, R.F., Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
dc.contributor.affiliation Bazarbachi, A., Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Azarpazhooh, M.R., Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran
dc.contributor.authorAddress Azarpazhooh, M. R.; Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Ahmadabad Boulevard, Mashhad, Iran; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Shoeibi, A
dc.contributor.authorInitials Rafatpanah, H
dc.contributor.authorInitials Azarpazhooh, A
dc.contributor.authorInitials Mokhber, N
dc.contributor.authorInitials Hedayati-Moghaddam, MR
dc.contributor.authorInitials Amiri, A
dc.contributor.authorInitials Hashemi, P
dc.contributor.authorInitials Foroghipour, M
dc.contributor.authorInitials Hoseini, RF
dc.contributor.authorInitials Bazarbachi, A
dc.contributor.authorInitials Azarpazhooh, MR
dc.contributor.authorReprintAddress Azarpazhooh, MR (reprint author), Mashhad Univ Med Sci, Ghaem Hosp, Fac Med, Dept Neurol, Ahmadabad Blvd, Mashhad, Iran.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedTotWOSCount 0
dc.description.citedWOSCount 0
dc.format.extentCount 7
dc.identifier.coden ANUBB
dc.identifier.pubmedID 23568138
dc.identifier.scopusID 84891652484
dc.publisher.address TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
dc.relation.ispartOfISOAbbr Acta Neurol. Belg.
dc.relation.ispartOfIssue 4
dc.relation.ispartofPubTitle Acta Neurologica Belgica
dc.relation.ispartofPubTitleAbbr Acta Neurol. Belg.
dc.relation.ispartOfVolume 113
dc.source.ID WOS:000328091300010
dc.type.publication Journal
dc.subject.otherAuthKeyword Epidemiology
dc.subject.otherAuthKeyword HTLV-1
dc.subject.otherAuthKeyword Iran
dc.subject.otherAuthKeyword Paraparesis, tropical spastic
dc.subject.otherIndex adolescent
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex amyotrophic lateral sclerosis
dc.subject.otherIndex article
dc.subject.otherIndex autonomic dysfunction
dc.subject.otherIndex backache
dc.subject.otherIndex bladder disease
dc.subject.otherIndex blood transfusion
dc.subject.otherIndex breast feeding
dc.subject.otherIndex clinical feature
dc.subject.otherIndex constipation
dc.subject.otherIndex controlled study
dc.subject.otherIndex cross-sectional study
dc.subject.otherIndex dental procedure
dc.subject.otherIndex dialysis
dc.subject.otherIndex enzyme linked immunosorbent assay
dc.subject.otherIndex erectile dysfunction
dc.subject.otherIndex female
dc.subject.otherIndex gait disorder
dc.subject.otherIndex hospitalization
dc.subject.otherIndex human
dc.subject.otherIndex Human T cell leukemia virus 1
dc.subject.otherIndex human t cell leukemia virus 1 infection
dc.subject.otherIndex Iran
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex medical history
dc.subject.otherIndex motor performance
dc.subject.otherIndex muscle strength
dc.subject.otherIndex neurologic disease
dc.subject.otherIndex polymerase chain reaction
dc.subject.otherIndex prevalence
dc.subject.otherIndex questionnaire
dc.subject.otherIndex risk factor
dc.subject.otherIndex sensory dysfunction
dc.subject.otherIndex sex
dc.subject.otherIndex spasticity
dc.subject.otherIndex tattooing
dc.subject.otherIndex tropical spastic paraparesis
dc.subject.otherIndex Western blotting
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Aged
dc.subject.otherIndex Aged, 80 and over
dc.subject.otherIndex Cross-Sectional Studies
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Iran
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Paraparesis, Tropical Spastic
dc.subject.otherIndex Prevalence
dc.subject.otherIndex Registries
dc.subject.otherIndex Risk Factors
dc.subject.otherIndex Young Adult
dc.subject.otherKeywordPlus T-LYMPHOTROPIC VIRUS
dc.subject.otherKeywordPlus HTLV-I INFECTION
dc.subject.otherKeywordPlus CELL LEUKEMIA-VIRUS
dc.subject.otherKeywordPlus BLOOD-DONORS
dc.subject.otherKeywordPlus PREVALENCE
dc.subject.otherKeywordPlus MASHHAD
dc.subject.otherKeywordPlus POPULATION
dc.subject.otherKeywordPlus DISEASE
dc.subject.otherKeywordPlus ORIGIN
dc.subject.otherKeywordPlus TYPE-1
dc.subject.otherWOS Clinical Neurology
dc.subject.otherWOS Neurosciences

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