AUB ScholarWorks

Hemophagocytic syndrome as a presenting sign of transformation of smoldering to acute adult T-cell leukemia-lymphoma: Efficacy of anti-retroviral and interferon therapy

Show simple item record

dc.contributor.author Aouba A.
dc.contributor.author Lambotte O.
dc.contributor.author Vasiliu V.
dc.contributor.author Divine M.
dc.contributor.author Valensi F.
dc.contributor.author Varet B.
dc.contributor.author Bazarbachi A.
dc.contributor.author Hermine O.
dc.contributor.editor
dc.date Jun-2004
dc.date.accessioned 2017-10-05T15:38:40Z
dc.date.available 2017-10-05T15:38:40Z
dc.date.issued 2004
dc.identifier 10.1002/ajh.20065
dc.identifier.isbn
dc.identifier.issn 03618609
dc.identifier.uri http://hdl.handle.net/10938/16460
dc.description.abstract A 55-year-old Caribbean woman with a 6-year history of smoldering adult T-cell leukemia-lymphoma presented with clinical and biological symptoms of hemophagocytic syndrome. An extensive search for infectious diseases was negative. A lymph node biopsy showing large T-cell lymphoma (CD4-, CD25+) and findings of high LDH count and severe lymphocytosis led to the diagnosis of acute adult T-cell leukemia-lymphoma. Antiretroviral therapy combining zidovudine, lamivudine, and interferon-α was started, resulting in rapid control of both hemophagocytic syndrome and symptoms of acute adult T-cell leukemia-lymphoma. Thus, we propose that adult T-cell leukemia-lymphoma must be added to the spectrum of etiologies of hemophagocytic syndrome. © 2004 Wiley-Liss, Inc.
dc.format.extent
dc.format.extent Pages: (187-189)
dc.language English
dc.publisher HOBOKEN
dc.relation.ispartof Publication Name: American Journal of Hematology; Publication Year: 2004; Volume: 76; no. 2; Pages: (187-189);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Hemophagocytic syndrome as a presenting sign of transformation of smoldering to acute adult T-cell leukemia-lymphoma: Efficacy of anti-retroviral and interferon therapy
dc.type Article
dc.contributor.affiliation Aouba, A., Department of Haematology, Hôpital Necker-Enfants Malades, Paris, France, Department of Adult Haematology, Hôpital Necker-Enfants Malades, 149-161 rue de Sèvres, 75743 Paris Cedex 15, France
dc.contributor.affiliation Lambotte, O., Department of Haematology, Hôpital Necker-Enfants Malades, Paris, France
dc.contributor.affiliation Vasiliu, V., Department of Pathology, Hôpital Necker-Enfants Malades, Paris, France
dc.contributor.affiliation Divine, M., Department of Haematology, Hôpital Henri Mondor, Creteil, France
dc.contributor.affiliation Valensi, F., Department of Haematology, Hôpital Necker-Enfants Malades, Paris, France
dc.contributor.affiliation Varet, B., Department of Haematology, Hôpital Necker-Enfants Malades, Paris, France
dc.contributor.affiliation Bazarbachi, A., Department of Internal Medicine, Amer. University of Beirut (AUB-MC), Beirut, Lebanon
dc.contributor.affiliation Hermine, O., Department of Haematology, Hôpital Necker-Enfants Malades, Paris, France, Department of Adult Haematology, Hôpital Necker-Enfants Malades, 149-161 rue de Sèvres, 75743 Paris Cedex 15, France
dc.contributor.authorAddress Aouba, A.; Department of Adult Haematology, Hôpital Necker-Enfants Malades, 149-161 rue de Sèvres, 75743 Paris Cedex 15, France; email: achille.aouba@wanadoo.fr
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail achille.aouba@wanadoo.fr; hermine@necker.fr
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Aouba, A
dc.contributor.authorInitials Lambotte, O
dc.contributor.authorInitials Vasiliu, V
dc.contributor.authorInitials Divine, M
dc.contributor.authorInitials Valensi, F
dc.contributor.authorInitials Varet, B
dc.contributor.authorInitials Bazarbachi, A
dc.contributor.authorInitials Hermine, O
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Aouba, A (reprint author), Hop Necker Enfants Malad, Dept Adult Haematol, 149-161 Rue Sevres, F-75743 Paris 15, France.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited FRANCHINI G, 1995, BLOOD, V86, P3619; FUJIWARA F, 1993, AM J PEDIAT HEMATOL, V15, P92; HERMINE O, 1995, NEW ENGL J MED, V332, P1749, DOI 10.1056-NEJM199506293322604; Hermine Olivier, 2002, Hematol J, V3, P276, DOI 10.1038-sj.thj.6200195; Hermine O, 1998, BIODRUGS, V10, P447, DOI 10.2165-00063030-199810060-00003; Imashuku S, 1997, INT J HEMATOL, V66, P135; Inoue Y, 2000, J Dermatol, V27, P280; Otawa M, 2000, Rinsho Ketsueki, V41, P1254; REINER AP, 1988, MEDICINE, V67, P369; Roudier M, 1997, LEUKEMIA, V11, P453, DOI 10.1038-sj.leu.2400580
dc.description.citedCount 5
dc.description.citedTotWOSCount 2
dc.description.citedWOSCount 2
dc.format.extentCount 3
dc.identifier.articleNo
dc.identifier.coden AJHED
dc.identifier.pubmedID 15164389
dc.identifier.scopusID 2542528580
dc.identifier.url
dc.publisher.address DIV JOHN WILEY and SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Am. J. Hematol.
dc.relation.ispartOfIssue 2
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle American Journal of Hematology
dc.relation.ispartofPubTitleAbbr Am. J. Hematol.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 76
dc.source.ID WOS:000221814500017
dc.type.publication Journal
dc.subject.otherAuthKeyword Adult T-cell leukemia-lymphoma
dc.subject.otherAuthKeyword Hemophagocytic syndrome
dc.subject.otherAuthKeyword Human T lymphocyte virus type I
dc.subject.otherAuthKeyword Interferon-2α
dc.subject.otherAuthKeyword Lamivudine
dc.subject.otherAuthKeyword Zidovudine
dc.subject.otherChemCAS lamivudine, 134678-17-4, 134680-32-3
dc.subject.otherChemCAS zidovudine, 30516-87-1
dc.subject.otherChemCAS Antineoplastic Agents
dc.subject.otherChemCAS Antiviral Agents
dc.subject.otherChemCAS Interferon-alpha
dc.subject.otherChemCAS Lamivudine, 134678-17-4
dc.subject.otherChemCAS Zidovudine, 30516-87-1
dc.subject.otherIndex alpha2 interferon
dc.subject.otherIndex anthracycline
dc.subject.otherIndex lamivudine
dc.subject.otherIndex zidovudine
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex case report
dc.subject.otherIndex clinical feature
dc.subject.otherIndex depression
dc.subject.otherIndex diagnostic accuracy
dc.subject.otherIndex differential diagnosis
dc.subject.otherIndex drug efficacy
dc.subject.otherIndex fatigue
dc.subject.otherIndex female
dc.subject.otherIndex fever
dc.subject.otherIndex hemophagocytic syndrome
dc.subject.otherIndex human
dc.subject.otherIndex Human T cell leukemia virus 1
dc.subject.otherIndex lymph node biopsy
dc.subject.otherIndex lymphocytosis
dc.subject.otherIndex priority journal
dc.subject.otherIndex symptom
dc.subject.otherIndex T cell leukemia
dc.subject.otherIndex T cell lymphoma
dc.subject.otherIndex Antineoplastic Agents
dc.subject.otherIndex Antiviral Agents
dc.subject.otherIndex Drug Therapy, Combination
dc.subject.otherIndex Female
dc.subject.otherIndex Histiocytosis
dc.subject.otherIndex Humans
dc.subject.otherIndex Interferon-alpha
dc.subject.otherIndex Lamivudine
dc.subject.otherIndex Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Zidovudine
dc.subject.otherKeywordPlus LEUKEMIA
dc.subject.otherWOS Hematology


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search AUB ScholarWorks


Browse

My Account