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Severity of rheumatoid arthritis: The SEVERA study

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dc.contributor.author Baddoura R.
dc.contributor.author Haddad S.
dc.contributor.author Awada H.
dc.contributor.author Al-Masri A.F.
dc.contributor.author Merheb G.
dc.contributor.author Attoui S.
dc.contributor.author Okais J.
dc.contributor.author Messayke J.
dc.contributor.author Ghandour F.
dc.contributor.editor
dc.date 2006
dc.date.accessioned 2017-10-05T15:38:53Z
dc.date.available 2017-10-05T15:38:53Z
dc.date.issued 2006
dc.identifier 10.1007/s10067-005-0136-7
dc.identifier.isbn
dc.identifier.issn 07703198
dc.identifier.uri http://hdl.handle.net/10938/16582
dc.description.abstract This study aims to assess the severity of rheumatoid arthritis (RA) in rheumatology practice in our population. All outpatients and inpatients with RA seen by registered rheumatologists over a 1-year period were included. Severity was measured using the Larsen score for hands and wrists and the Modified Health Assessment Questionnaire (M-HAQ). Two hundred ninety-eight RA cases were included. Mean age was 51.5 years. Among them, 261 (87.6percent) were females. Disease duration was less than a year in 26 subjects (8.7percent) and 10 years and above in 108 (36.2percent) with a mean of 8.9. There were 220 (73.8percent) subjects who had M-HAQ score 1. In 61 (20.5percent) subjects, M-HAQ score was ≥1 and 2, and 17 (5.7percent) had M-HAQ score ≥2. In relation with disease duration, M-HAQ starts with an average (SD) value of 0.7 (0.6) during the first year, decreases to 0.4 (0.4) at 5-year disease duration and increases after 10 years of disease progression to an average of 0.9 (0.8). Mean (SD) Larsen score was 51.9 (29.5) and median was 45. A total of 25percent had a Larsen score ≥50percent of maximum. Larsen score increased significantly (p0.0001) with disease duration, starting at an average (SD) of 36.1 (14.9) during the first year, rising to 42.5 (15.8) around 5 years and reaching 73.9 (36.9) after 10 years. RA severity in our practice is comparable to that reported in Western populations in terms of radiological damage; however, functional status differs, possibly reflecting cultural differences. © Clinical Rheumatology 2006.
dc.format.extent
dc.format.extent Pages: (700-704)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Clinical Rheumatology; Publication Year: 2006; Volume: 25; no. 5; Pages: (700-704);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Severity of rheumatoid arthritis: The SEVERA study
dc.type Article
dc.contributor.affiliation Baddoura, R., Rheumatology Department, Hotel-Dieu Hospital, St. Joseph University, Beirut, Lebanon
dc.contributor.affiliation Haddad, S., Radiology Department, Hotel-Dieu Hospital, St. Joseph University, Beirut, Lebanon
dc.contributor.affiliation Awada, H., Rheumatology Department, Hotel-Dieu Hospital, St. Joseph University, Beirut, Lebanon
dc.contributor.affiliation Al-Masri, A.F., Rheumatology Department, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Merheb, G., Rheumatology Department, Notre-Dame de Secours Hospital, Byblos, Lebanon
dc.contributor.affiliation Attoui, S., Rheumatology Department, Lebanese Govermental Hospital, Beirut, Lebanon
dc.contributor.affiliation Okais, J., Rheumatology Department, Hotel-Dieu Hospital, St. Joseph University, Beirut, Lebanon
dc.contributor.affiliation Messayke, J., Rheumatology Private Clinic, Tripoli, Lebanon
dc.contributor.affiliation Ghandour, F., Rheumatology Private Clinic, Nabatieh, Lebanon
dc.contributor.authorAddress Baddoura, R.; Rheumatology Department, Hotel-Dieu Hospital, St. Joseph University, Beirut, Lebanon; email: rbaddoura@usj.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Rheumatology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Rheumatology
dc.contributor.authorEmail rbaddoura@usj.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Baddoura, R
dc.contributor.authorInitials Haddad, S
dc.contributor.authorInitials Awada, H
dc.contributor.authorInitials Al-Masri, AF
dc.contributor.authorInitials Merheb, G
dc.contributor.authorInitials Attoui, S
dc.contributor.authorInitials Okais, J
dc.contributor.authorInitials Messayke, J
dc.contributor.authorInitials Ghandour, F
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Baddoura, R (reprint author), St Josephs Univ, Dept Rheumatol, Hotel Dieu Hosp, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Arnett FC, 1988, ARTHRITIS RHEUM, V31, P315; Barrett EM, 2000, RHEUMATOLOGY, V39, P1403, DOI 10.1093-rheumatology-39.12.1403; Bitar E, 1969, Rev Rhum Mal Osteoartic, V36, P84; Boini S, 2001, ANN RHEUM DIS, V60, P817; DARWISH MJ, 1987, INT J EPIDEMIOL, V16, P420, DOI 10.1093-ije-16.3.420; Drossaers-Bakker KW, 2000, RHEUMATOLOGY, V39, P998, DOI 10.1093-rheumatology-39.9.998; EBERHARDT KB, 1995, J RHEUMATOL, V22, P1037; Fex E, 1996, BRIT J RHEUMATOL, V35, P1106; FRIES JF, 1980, ARTHRITIS RHEUM, V23, P137, DOI 10.1002-art.1780230202; Graudal NA, 1998, ARTHRITIS RHEUM, V41, P1470, DOI 10.1002-1529-0131(199808)41:81470::AID-ART183.0.CO;2-V; HAKALA M, 1994, J RHEUMATOL, V21, P1432; Harrison B, 2000, RHEUMATOLOGY, V39, P939, DOI 10.1093-rheumatology-39.9.939; Kaarela K, 1997, J RHEUMATOL, V24, P1285; LARSEN A, 1977, ACTA RADIOL DIAGN, V18, P481; Lassere M, 1997, J RHEUMATOL, V24, P1288; Lindqvist E, 2002, ANN RHEUM DIS, V61, P1055, DOI 10.1136-ard.61.12.1055; Minaur NJ, 2004, J RHEUMATOL, V31, P3; PINCUS T, 1984, ARTHRITIS RHEUM, V27, P864, DOI 10.1002-art.1780270805; PINCUS T, 1983, ARTHRITIS RHEUM, V26, P1346, DOI 10.1002-art.1780261107; PINKUS T, 1994, J RHEUMATOL, V21, P1385; Plant MJ, 1998, J RHEUMATOL, V25, P417; RASKER JJ, 1984, CLIN RHEUMATOL, V3, P11, DOI 10.1007-BF02715690; Saraux A, 2001, ARTHRITIS RHEUM, V44, P2485, DOI 10.1002-1529-0131(200111)44:112485::AID-ART4283.0.CO;2-S; SHARP JT, 1991, ARTHRITIS RHEUM, V34, P660, DOI 10.1002-art.1780340606; SHARP JT, 1989, ARTHRITIS RHEUM, V32, P221, DOI 10.1002-anr.1780320218; Sokka T, 1999, J RHEUMATOL, V26, P1681; Stucki G, 2004, ANN RHEUM DIS, V63, P40, DOI 10.1136-ard.2004.028233; SUAREZALMAZOR ME, 1994, J RHEUMATOL, V21, P1438; Suurmeijer TPBM, 2001, ARTHRIT RHEUM-ARTHR, V45, P111; SYMMONS DPM, 1995, BAILLIERE CLIN RHEUM, V9, P267, DOI 10.1016-S0950-3579(05)80190-6; VANDERHEIJDE DMFM, 1992, ARTHRITIS RHEUM, V35, P26; Wiles NJ, 2001, ANN RHEUM DIS, V60, P956, DOI 10.1136-ard.60.10.956; Wolfe F, 2001, J RHEUMATOL, V28, P1453; Wolfe F, 1998, J RHEUMATOL, V25, P2108; Wolfe F, 2001, ANN RHEUM DIS, V60, P994, DOI 10.1136-ard.60.11.994; YOUNG A, 1991, ARTHRITIS RHEUM; Zijlstra TR, 2002, ANN RHEUM DIS, V61, P20, DOI 10.1136-ard.61.1.20
dc.description.citedCount 4
dc.description.citedTotWOSCount 4
dc.description.citedWOSCount 4
dc.format.extentCount 5
dc.identifier.articleNo
dc.identifier.coden CLRHD
dc.identifier.pubmedID 16362443
dc.identifier.scopusID 33746340615
dc.identifier.url
dc.publisher.address 233 SPRING STREET, NEW YORK, NY 10013 USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Clin. Rheumatol.
dc.relation.ispartOfIssue 5
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Clinical Rheumatology
dc.relation.ispartofPubTitleAbbr Clin. Rheumatol.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 25
dc.source.ID WOS:000239171500015
dc.type.publication Journal
dc.subject.otherAuthKeyword Disease activity
dc.subject.otherAuthKeyword Disease severity
dc.subject.otherAuthKeyword Larsen's score
dc.subject.otherAuthKeyword M-HAQ
dc.subject.otherAuthKeyword Rheumatoid arthritis
dc.subject.otherChemCAS
dc.subject.otherIndex disease modifying antirheumatic drug
dc.subject.otherIndex steroid
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex article
dc.subject.otherIndex bone radiography
dc.subject.otherIndex controlled study
dc.subject.otherIndex cultural factor
dc.subject.otherIndex disease course
dc.subject.otherIndex disease severity
dc.subject.otherIndex female
dc.subject.otherIndex functional assessment
dc.subject.otherIndex hand disease
dc.subject.otherIndex hospital patient
dc.subject.otherIndex human
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex outpatient
dc.subject.otherIndex priority journal
dc.subject.otherIndex questionnaire
dc.subject.otherIndex rheumatoid arthritis
dc.subject.otherIndex scoring system
dc.subject.otherIndex Western Hemisphere
dc.subject.otherIndex wrist disease
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Aged
dc.subject.otherIndex Aged, 80 and over
dc.subject.otherIndex Arthritis, Rheumatoid
dc.subject.otherIndex Arthrography
dc.subject.otherIndex Cross-Cultural Comparison
dc.subject.otherIndex Cross-Sectional Studies
dc.subject.otherIndex Disease Progression
dc.subject.otherIndex Female
dc.subject.otherIndex Health Status
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Severity of Illness Index
dc.subject.otherIndex Wrist Joint
dc.subject.otherKeywordPlus HEALTH ASSESSMENT QUESTIONNAIRE
dc.subject.otherKeywordPlus PROSPECTIVE FOLLOW-UP
dc.subject.otherKeywordPlus RADIOGRAPHIC DAMAGE
dc.subject.otherKeywordPlus WORK DISABILITY
dc.subject.otherKeywordPlus DISEASE
dc.subject.otherKeywordPlus PROGRESSION
dc.subject.otherKeywordPlus COMMUNITY
dc.subject.otherKeywordPlus COHORT
dc.subject.otherKeywordPlus CLASSIFICATION
dc.subject.otherKeywordPlus BENCHMARKING
dc.subject.otherWOS Rheumatology


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