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Cardiac sarcoidosis responding to monotherapy with infliximab

Show simple item record Uthman I. Touma Z. Khoury M.
dc.contributor.editor Nov-2007 2017-10-05T15:39:05Z 2017-10-05T15:39:05Z 2007
dc.identifier 10.1007/s10067-007-0614-1
dc.identifier.issn 07703198
dc.description.abstract Cardiac involvement is a rare and potentially life-threatening complication of sarcoidosis. We report the case of a young previously healthy woman who presented with complete atrioventricular heart block. Further evaluation revealed non-caseating granulomas in the hilar and mediastinal regions. A pacemaker was inserted, and she was treated with four doses of infliximab after she refused treatment with steroids. Rapid resolution of the pulmonary lymph nodes was documented and repeated interrogations of the pacemaker 1 year after her last infliximab infusion documented that she was in sinus rhythm. Infliximab may be considered as an alternative first-line therapy in sarcoidosis with serious organ involvement. © Clinical Rheumatology 2007.
dc.format.extent Pages: (2001-2003)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Clinical Rheumatology; Publication Year: 2007; Volume: 26; no. 11; Pages: (2001-2003);
dc.source Scopus
dc.title Cardiac sarcoidosis responding to monotherapy with infliximab
dc.type Article
dc.contributor.affiliation Uthman, I., Department of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, Hamra Street, Beirut 1103 2090, Lebanon
dc.contributor.affiliation Touma, Z., Department of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, Hamra Street, Beirut 1103 2090, Lebanon
dc.contributor.affiliation Khoury, M., Department of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, Hamra Street, Beirut 1103 2090, Lebanon
dc.contributor.authorAddress Uthman, I.; Department of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, Hamra Street, Beirut 1103 2090, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Uthman, I
dc.contributor.authorInitials Touma, Z
dc.contributor.authorInitials Khoury, M
dc.contributor.authorReprintAddress Uthman, I (reprint author), Amer Univ Beirut, Ctr Med, Dept Internal Med, Fac Med, Hamra St 1103, Beirut 2090, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 32
dc.description.citedTotWOSCount 24
dc.description.citedWOSCount 23
dc.format.extentCount 3
dc.identifier.coden CLRHD
dc.identifier.pubmedID 17394036
dc.identifier.scopusID 34948841526
dc.publisher.address 233 SPRING STREET, NEW YORK, NY 10013 USA
dc.relation.ispartOfISOAbbr Clin. Rheumatol.
dc.relation.ispartOfIssue 11
dc.relation.ispartofPubTitle Clinical Rheumatology
dc.relation.ispartofPubTitleAbbr Clin. Rheumatol.
dc.relation.ispartOfVolume 26
dc.source.ID WOS:000249813700044
dc.type.publication Journal
dc.subject.otherAuthKeyword Heart block
dc.subject.otherAuthKeyword Infliximab
dc.subject.otherAuthKeyword Sarcoidosis
dc.subject.otherAuthKeyword Tumor necrosis factor
dc.subject.otherChemCAS infliximab, 170277-31-3
dc.subject.otherChemCAS Antibodies, Monoclonal
dc.subject.otherChemCAS Antirheumatic Agents
dc.subject.otherChemCAS infliximab
dc.subject.otherIndex corticosteroid
dc.subject.otherIndex infliximab
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex artificial heart pacemaker
dc.subject.otherIndex atrioventricular block
dc.subject.otherIndex bradycardia
dc.subject.otherIndex bronchoscopy
dc.subject.otherIndex case report
dc.subject.otherIndex clinical feature
dc.subject.otherIndex drug response
dc.subject.otherIndex electrocardiogram
dc.subject.otherIndex female
dc.subject.otherIndex human
dc.subject.otherIndex human tissue
dc.subject.otherIndex lung biopsy
dc.subject.otherIndex lung granuloma
dc.subject.otherIndex monotherapy
dc.subject.otherIndex priority journal
dc.subject.otherIndex sarcoidosis
dc.subject.otherIndex Adult
dc.subject.otherIndex Antibodies, Monoclonal
dc.subject.otherIndex Antirheumatic Agents
dc.subject.otherIndex Female
dc.subject.otherIndex Heart Block
dc.subject.otherIndex Heart Diseases
dc.subject.otherIndex Humans
dc.subject.otherIndex Lymph Nodes
dc.subject.otherIndex Myocardium
dc.subject.otherIndex Sarcoidosis
dc.subject.otherIndex Treatment Outcome
dc.subject.otherKeywordPlus NECROSIS-FACTOR-ALPHA
dc.subject.otherKeywordPlus THERAPY
dc.subject.otherWOS Rheumatology

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