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Validation of the multiple sclerosis international quality of life questionnaire

Show simple item record Simeoni M.C. Auquier P. Fernandez O. Flachenecker P. Stecchi S. Constantinescu C.S. Idiman E. Boyko A.N. Beiske A.G. Vollmer T. Triantafyllou N. O'Connor P. Barak Y. Biermann L. Cristiano E. Atweh S. Patrick D.L. Robitail S. Ammoury N.
dc.contributor.editor Mar-2008 2017-10-05T15:39:10Z 2017-10-05T15:39:10Z 2008
dc.identifier 10.1177/1352458507080733
dc.identifier.issn 13524585
dc.description.abstract This study aims to validate the Multiple Sclerosis (MS) International Quality of Life (MusiQoL) questionnaire, a multi-dimensional, self-administered questionnaire, available in 14 languages, as a disease-specific quality of life scale that can be applied internationally. A total of 1992 patients with different types and severities of MS from 15 countries were recruited. At baseline and day 21 ± 7, each patient completed the MusiQoL, a symptom checklist and the short-form (SF)-36 QoL questionnaire. Neurologists also collected socio-demographic, MS history and outcome data. The database was randomly divided into two subgroups and analysed according to different patient characteristics. For each model, psychometric properties were tested and the number of items was reduced by various statistical methods. Construct validity, internal consistency, reproducibility and external consistency were also tested. Nine dimensions, explaining 71percent of the total variance, were isolated. Internal consistency and reproducibility were satisfactory for all the dimensions. External validity testing revealed that dimension scores correlated significantly with all SF-36 scores, but showed discriminant validity by gender, socio-economic and health status. Significant correlations were found between activity in daily life scores and clinical indices. These results demonstrate the validity and reliability of the MusiQoL as an international scale to evaluate QoL in patients with MS. © 2008 SAGE Publications Los Angeles, London, New Delhi and Singapore.
dc.format.extent Pages: (219-230)
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: Multiple Sclerosis; Publication Year: 2008; Volume: 14; no. 2; Pages: (219-230);
dc.source Scopus
dc.title Validation of the multiple sclerosis international quality of life questionnaire
dc.type Article
dc.contributor.affiliation Simeoni, M.C., Department of Public Health, Timone University Hospital, Marseille, France
dc.contributor.affiliation Auquier, P., Department of Public Health, Timone University Hospital, Marseille, France, Service de Santé Publique, Faculté de Médecine, 27, bd Jean Moulin, 13385 Marseille, France
dc.contributor.affiliation Fernandez, O., Hospital Regional Universitario Carlos Haya, Málaga, Spain
dc.contributor.affiliation Flachenecker, P., Department of Neurology, University of Würzburg, Würzburg, Germany, Neurological Rehabilitation Center Quellenhof, Bad Wildbad, Würzburg, Germany
dc.contributor.affiliation Stecchi, S., Centro SM, Villa Mazzacorati, Bologna, Italy
dc.contributor.affiliation Constantinescu, C.S., Division of Clinical Neurology, University Hospital, University of Nottingham, Nottingham, United Kingdom
dc.contributor.affiliation Idiman, E., Dokuz Eylül Üniversity, Department of Neurology, Izmir, Turkey
dc.contributor.affiliation Boyko, A.N., Department of Neurology, Russian State Medical University, Moscow, Russian Federation
dc.contributor.affiliation Beiske, A.G., Department of Neurology, Akershus University Hospital, Lørenskog, Norway
dc.contributor.affiliation Vollmer, T., Division of Neurology, Barrow Neurological Institute, Phoenix, AZ, United States
dc.contributor.affiliation Triantafyllou, N., Department of Neurology, Aignition Hospital, University of Athens, Athens, Greece
dc.contributor.affiliation O'Connor, P., St Michael's Hospital, University of Toronto, Toronto, ON, Canada
dc.contributor.affiliation Barak, Y., SHEBA MC, Tel-HaShomer and the Sackler School of Medicine, Tel Aviv, Israel
dc.contributor.affiliation Biermann, L., P.O. Box 12605, Queenswood, South Africa
dc.contributor.affiliation Cristiano, E., Department of Neurology, University of Buenos Aires, Head Neurology Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
dc.contributor.affiliation Atweh, S., Internal Medicine Department, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Patrick, D.L., Department of Neurology, University of Washington, Seattle, WA, United States
dc.contributor.affiliation Robitail, S., Department of Public Health, Timone University Hospital, Marseille, France
dc.contributor.affiliation Ammoury, N., Serono International S.A., Geneva, Switzerland
dc.contributor.affiliation Beresniak, A., Laboratory of Applied Health Economics LIRAES, University of Paris 5, Paris, France
dc.contributor.affiliation Pelletier, J., Department of Neurology, Timone University Hospital, Marseille, France
dc.contributor.affiliation Edgardo, C.
dc.contributor.affiliation Liliana, P.
dc.contributor.affiliation Jorge, C.
dc.contributor.affiliation Marcela, F.
dc.contributor.affiliation Callegaro, D.
dc.contributor.affiliation Côté, J.-P.
dc.contributor.affiliation Triantafillou, A.
dc.contributor.affiliation Barak, Y.
dc.contributor.affiliation Bloch, I.
dc.contributor.affiliation Reshef, A.
dc.contributor.affiliation Gilad, R.
dc.contributor.affiliation Stecchi, S.
dc.contributor.affiliation Beiske, A.
dc.contributor.affiliation Drulovic, J.
dc.contributor.affiliation Biermann, L.
dc.contributor.affiliation Fernandez, O.
dc.contributor.affiliation Idiman, E.
dc.contributor.authorAddress Auquier, P.; Service de Santé Publique, Faculté de Médecine, 27 bd Jean Moulin, 13385 Marseille, France; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Neurology;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Neurology
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Simeoni, MC
dc.contributor.authorInitials Auquier, P
dc.contributor.authorInitials Fernandez, O
dc.contributor.authorInitials Flachenecker, P
dc.contributor.authorInitials Stecchi, S
dc.contributor.authorInitials Constantinescu, CS
dc.contributor.authorInitials Idiman, E
dc.contributor.authorInitials Boyko, A
dc.contributor.authorInitials Beiske, AG
dc.contributor.authorInitials Vollmer, T
dc.contributor.authorInitials Triantafyllou, N
dc.contributor.authorInitials O'Connor, P
dc.contributor.authorInitials Barak, Y
dc.contributor.authorInitials Biermann, L
dc.contributor.authorInitials Cristiano, E
dc.contributor.authorInitials Atweh, S
dc.contributor.authorInitials Patrick, DL
dc.contributor.authorInitials Robitail, S
dc.contributor.authorInitials Ammoury, N
dc.contributor.authorInitials Beresn
dc.contributor.authorReprintAddress Auquier, P (reprint author), Fac Med Marseille, Serve Sante Publ, 27 bd Jean Moulin, F-13385 Marseille, France.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 41
dc.description.citedTotWOSCount 40
dc.description.citedWOSCount 40
dc.format.extentCount 12
dc.identifier.coden MUSCF
dc.identifier.pubmedID 17942521
dc.identifier.scopusID 43149122517
dc.publisher.address 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
dc.relation.ispartOfISOAbbr Mult. Scler. J.
dc.relation.ispartOfIssue 2
dc.relation.ispartofPubTitle Multiple Sclerosis
dc.relation.ispartofPubTitleAbbr Mult. Scler.
dc.relation.ispartOfVolume 14
dc.source.ID WOS:000254216600011
dc.type.publication Journal
dc.subject.otherAuthKeyword International
dc.subject.otherAuthKeyword Multiple sclerosis
dc.subject.otherAuthKeyword MusiQol
dc.subject.otherAuthKeyword Quality of life
dc.subject.otherAuthKeyword Questionnaire
dc.subject.otherAuthKeyword Validation
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex article
dc.subject.otherIndex clinical assessment tool
dc.subject.otherIndex correlation analysis
dc.subject.otherIndex daily life activity
dc.subject.otherIndex demography
dc.subject.otherIndex disease severity
dc.subject.otherIndex female
dc.subject.otherIndex health care quality
dc.subject.otherIndex health status
dc.subject.otherIndex human
dc.subject.otherIndex internal consistency
dc.subject.otherIndex internal validity
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex multiple sclerosis
dc.subject.otherIndex Multiple sclerosis International Quality of Life Questionnaire
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex psychometry
dc.subject.otherIndex quality of life
dc.subject.otherIndex questionnaire
dc.subject.otherIndex reliability
dc.subject.otherIndex reproducibility
dc.subject.otherIndex Short Form 36
dc.subject.otherIndex social status
dc.subject.otherIndex validity
dc.subject.otherIndex Female
dc.subject.otherIndex Health Status
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Multiple Sclerosis
dc.subject.otherIndex Psychometrics
dc.subject.otherIndex Quality of Life
dc.subject.otherIndex Questionnaires
dc.subject.otherIndex Reproducibility of Results
dc.subject.otherIndex Sensitivity and Specificity
dc.subject.otherIndex World Health
dc.subject.otherKeywordPlus DISABILITY STATUS SCALE
dc.subject.otherKeywordPlus DIAGNOSTIC-CRITERIA
dc.subject.otherKeywordPlus OUTCOME MEASURE
dc.subject.otherKeywordPlus HEALTH-STATUS
dc.subject.otherKeywordPlus MS
dc.subject.otherKeywordPlus PEOPLE
dc.subject.otherKeywordPlus GUIDELINES
dc.subject.otherKeywordPlus VALIDITY
dc.subject.otherKeywordPlus IMPACT
dc.subject.otherKeywordPlus SCHIZOPHRENIA
dc.subject.otherWOS Clinical Neurology

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