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Sustained improvement in cognitive and emotional status of apneic patients after prolonged treatment with positive airway pressure

Show simple item record Joseph S. Zuriqat M. Husari A.
dc.contributor.editor Jun-2009 2017-10-05T15:39:21Z 2017-10-05T15:39:21Z 2009
dc.identifier 10.1097/SMJ.0b013e3181a3a03b
dc.identifier.issn 00384348
dc.description.abstract Background: Obstructive sleep apnea-hypopnea syndrome (OSAH) is associated with impairment of cognitive functions and disturbances in emotional status. The aim of this study was to objectively evaluate the benefits of prolonged and sustained treatment for OSAH at two sleep centers serving rural community hospitals. Methods: Fifty-six patients diagnosed with OSAH syndrome underwent Cognistat, Beck Depression Inventory (BDI) and Millon Behavioral Medicine Diagnostic Inventory (MBMD) testing before initiation of treatment. Repeated testing after six months of therapy with positive airway pressure (PAP) was performed. Results: Significant improvements were noted in the BDI scale scores and a reduction in the MBMD scores reflected initial abnormal clinical personal symptoms that improved with treatment. MBMD analysis showed subjects with fewer symptoms of anxiety post baseline, which were sustained at 6 months post-treatment. Memory function improved as reflected by performance on the Cognistat. Women were observed to have a higher post-treatment BDI and younger patients appeared to have more shifts for improvement than older subjects in depressive symptomatology. Conclusions: These results indicate that prolonged and sustained PAP therapy is effective in restoring some of the deficiencies in patients with OSAH, particularly in terms of memory, depression, anxiety and increased psychological pathology. Copyright © 2009 by The Southern Medical Association.
dc.format.extent Pages: (589-594)
dc.language English
dc.publisher PHILADELPHIA
dc.relation.ispartof Publication Name: Southern Medical Journal; Publication Year: 2009; Volume: 102; no. 6; Pages: (589-594);
dc.source Scopus
dc.title Sustained improvement in cognitive and emotional status of apneic patients after prolonged treatment with positive airway pressure
dc.type Article
dc.contributor.affiliation Joseph, S.
dc.contributor.affiliation Zuriqat, M.
dc.contributor.affiliation Husari, A., Division of Pulmonary and Critical Care Medicine, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Husari, A.; Division of Pulmonary and Critical Care Medicine, American University of Beirut Medical Center, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Pulmonary and Critical Care Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Pulmonary and Critical Care Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Joseph, S
dc.contributor.authorInitials Zuriqat, M
dc.contributor.authorInitials Husari, A
dc.contributor.authorReprintAddress Husari, A (reprint author), Amer Univ Beirut, Med Ctr, Div Pulm and Crit Care Med, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 7
dc.description.citedTotWOSCount 6
dc.description.citedWOSCount 5
dc.format.extentCount 6
dc.identifier.coden SMJOA
dc.identifier.pubmedID 19434037
dc.identifier.scopusID 68049113654
dc.publisher.address 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
dc.relation.ispartOfISOAbbr South.Med.J.
dc.relation.ispartOfIssue 6
dc.relation.ispartofPubTitle Southern Medical Journal
dc.relation.ispartofPubTitleAbbr South. Med. J.
dc.relation.ispartOfVolume 102
dc.source.ID WOS:000266785300011
dc.type.publication Journal
dc.subject.otherAuthKeyword Cognitive and emotional disturbances
dc.subject.otherAuthKeyword Positive airway pressure
dc.subject.otherAuthKeyword Sleep apnea
dc.subject.otherAuthKeyword Therapy
dc.subject.otherIndex adult
dc.subject.otherIndex airway pressure
dc.subject.otherIndex anxiety disorder
dc.subject.otherIndex article
dc.subject.otherIndex Beck Depression Inventory
dc.subject.otherIndex cognition
dc.subject.otherIndex community hospital
dc.subject.otherIndex controlled study
dc.subject.otherIndex daytime somnolence
dc.subject.otherIndex depression
dc.subject.otherIndex disease association
dc.subject.otherIndex emotion
dc.subject.otherIndex fatigue
dc.subject.otherIndex female
dc.subject.otherIndex human
dc.subject.otherIndex hypertension
dc.subject.otherIndex irritability
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex memory
dc.subject.otherIndex mental performance
dc.subject.otherIndex millon behavioral medicine diagnostic inventory
dc.subject.otherIndex rating scale
dc.subject.otherIndex restlessness
dc.subject.otherIndex rural population
dc.subject.otherIndex scoring system
dc.subject.otherIndex sleep apnea syndrome
dc.subject.otherIndex symptom
dc.subject.otherIndex symptomatology
dc.subject.otherIndex treatment duration
dc.subject.otherIndex Adult
dc.subject.otherIndex Cognition
dc.subject.otherIndex Emotions
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Memory
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Neuropsychological Tests
dc.subject.otherIndex Positive-Pressure Respiration
dc.subject.otherIndex Psychiatric Status Rating Scales
dc.subject.otherIndex Questionnaires
dc.subject.otherIndex Sleep Apnea Syndromes
dc.subject.otherKeywordPlus OBSTRUCTIVE SLEEP-APNEA
dc.subject.otherKeywordPlus POPULATION
dc.subject.otherKeywordPlus DEPRESSION
dc.subject.otherKeywordPlus ANXIETY
dc.subject.otherKeywordPlus DISORDERS
dc.subject.otherKeywordPlus SYMPTOMS
dc.subject.otherKeywordPlus INSOMNIA
dc.subject.otherKeywordPlus RISK
dc.subject.otherWOS Medicine, General and Internal

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