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Acute coronary syndromes: Clinical characteristics, management, and outcomes at the American University of Beirut Medical Center, 2002-2005

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dc.contributor.author Abdallah M.
dc.contributor.author Karrowni W.
dc.contributor.author Shamseddeen W.
dc.contributor.author Itani S.
dc.contributor.author Kobeissi L.
dc.contributor.author Ghazzal Z.
dc.contributor.author Alam S.
dc.contributor.author Dakik H.A.
dc.contributor.editor
dc.date Jan-2010
dc.date.accessioned 2017-10-05T15:39:35Z
dc.date.available 2017-10-05T15:39:35Z
dc.date.issued 2010
dc.identifier 10.1002/clc.20636
dc.identifier.isbn
dc.identifier.issn 01609289
dc.identifier.uri http://hdl.handle.net/10938/16975
dc.description.abstract Objectives: Data on acute coronary syndromes (ACS) in developing countries is scarce. In this report, we analyze the temporal trends in the management and outcomes of a large series of ACS patients hospitalized at the American University of Beirut Medical Center (AUBMC), a tertiary referral university hospital located in a middle income Middle Eastern developing country. Methods: A total of 1025 consecutive patients hospitalized and discharged with the diagnosis of ACS were enrolled between 2002 and 2005. The utilization of evidence-based therapies and in-hospital outcomes were determined. Results: The study enrolled 228 patients (22percent) with ST-elevationmyocardial infarction (STEMI), 275 patients (27percent)with non-ST-elevationmyocardial infarction (NSTEMI), and 522 patients (51percent)with unstable angina. The STEMI group was younger and had a higher percentage ofmen. The utilization rates of coronary angiography and percutaneouscoronary intervention(PCI)were highest in the STEMI group. Comparison to earlierACS data (1997-1998) from the same hospital, showed an increase in the utilization of reperfusion therapy, coronary angioplasty, bypass surgery, aspirin, β-blockers, angiotensin-convertingenzymes (ACE), angiotensin receptor blockers (ARB), and statins over the past decade (P .05). This was associatedwith a significant decrease in hospitalmortality (13percent-7.7percent, P .01). Conclusions: This study analyzes one of the largest series of ACS patients reported from a single center in a developing country. The utilization of evidence-based therapies in the management of ACS at AUBMC has improved significantly over the past decade with an associated decrease in hospitalmortality. © 2010 Wiley Periodicals, Inc.
dc.format.extent
dc.language English
dc.relation.ispartof Publication Name: Clinical Cardiology; Publication Year: 2010; Volume: 33; no. 1;
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Acute coronary syndromes: Clinical characteristics, management, and outcomes at the American University of Beirut Medical Center, 2002-2005
dc.type Article
dc.contributor.affiliation Abdallah, M., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Karrowni, W., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Shamseddeen, W., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Itani, S., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Kobeissi, L., Department of Epidemiology and Population Health, American University of Beirut, Lebanon
dc.contributor.affiliation Ghazzal, Z., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Alam, S., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.affiliation Dakik, H.A., Department of Internal Medicine, American University of Beirut, Lebanon
dc.contributor.authorAddress Dakik, H. A.; Department of Medicine, American University of Beirut, PO Box 11-0236-A38, Beirut, Lebanon; email: hd01@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials empty
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited
dc.description.citedCount 7
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dc.identifier.articleNo
dc.identifier.coden CLCAD
dc.identifier.pubmedID 20014175
dc.identifier.scopusID 74949107543
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dc.publisher.address
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dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
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dc.relation.ispartOfISOAbbr
dc.relation.ispartOfIssue 1
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Clinical Cardiology
dc.relation.ispartofPubTitleAbbr Clin. Cardiol.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 33
dc.source.ID
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1
dc.subject.otherChemCAS amiodarone, 1951-25-3, 19774-82-4, 62067-87-2
dc.subject.otherChemCAS clopidogrel, 113665-84-2, 120202-66-6, 90055-48-4, 94188-84-8
dc.subject.otherChemCAS digoxin, 20830-75-5, 57285-89-9
dc.subject.otherChemCAS dobutamine, 34368-04-2, 52663-81-7
dc.subject.otherChemCAS dopamine, 51-61-6, 62-31-7
dc.subject.otherChemCAS heparin, 37187-54-5, 8057-48-5, 8065-01-8, 9005-48-5
dc.subject.otherChemCAS Adrenergic beta-Antagonists
dc.subject.otherChemCAS Angiotensin Receptor Antagonists
dc.subject.otherChemCAS Angiotensin-Converting Enzyme Inhibitors
dc.subject.otherChemCAS Antihypertensive Agents
dc.subject.otherChemCAS Aspirin, 50-78-2
dc.subject.otherChemCAS Hydroxymethylglutaryl-CoA Reductase Inhibitors
dc.subject.otherChemCAS Platelet Aggregation Inhibitors
dc.subject.otherIndex acetylsalicylic acid
dc.subject.otherIndex amiodarone
dc.subject.otherIndex angiotensin receptor antagonist
dc.subject.otherIndex beta adrenergic receptor blocking agent
dc.subject.otherIndex calcium channel blocking agent
dc.subject.otherIndex clopidogrel
dc.subject.otherIndex digoxin
dc.subject.otherIndex dipeptidyl carboxypeptidase inhibitor
dc.subject.otherIndex diuretic agent
dc.subject.otherIndex dobutamine
dc.subject.otherIndex dopamine
dc.subject.otherIndex fibric acid derivative
dc.subject.otherIndex fibrinogen receptor antagonist
dc.subject.otherIndex fibrinolytic agent
dc.subject.otherIndex heparin
dc.subject.otherIndex hydroxymethylglutaryl coenzyme A reductase inhibitor
dc.subject.otherIndex low molecular weight heparin
dc.subject.otherIndex nitric acid derivative
dc.subject.otherIndex acute coronary syndrome
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex angiocardiography
dc.subject.otherIndex article
dc.subject.otherIndex clinical feature
dc.subject.otherIndex controlled study
dc.subject.otherIndex coronary artery bypass surgery
dc.subject.otherIndex drug utilization
dc.subject.otherIndex evidence based medicine
dc.subject.otherIndex female
dc.subject.otherIndex health care utilization
dc.subject.otherIndex heart infarction
dc.subject.otherIndex heart muscle reperfusion
dc.subject.otherIndex human
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex mortality
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex percutaneous coronary intervention
dc.subject.otherIndex ST segment elevation
dc.subject.otherIndex transluminal coronary angioplasty
dc.subject.otherIndex university hospital
dc.subject.otherIndex unstable angina pectoris
dc.subject.otherIndex Acute Coronary Syndrome
dc.subject.otherIndex Adrenergic beta-Antagonists
dc.subject.otherIndex Aged
dc.subject.otherIndex Angioplasty, Balloon
dc.subject.otherIndex Angiotensin Receptor Antagonists
dc.subject.otherIndex Angiotensin-Converting Enzyme Inhibitors
dc.subject.otherIndex Antihypertensive Agents
dc.subject.otherIndex Aspirin
dc.subject.otherIndex Coronary Angiography
dc.subject.otherIndex Coronary Artery Bypass
dc.subject.otherIndex Evidence-Based Practice
dc.subject.otherIndex Female
dc.subject.otherIndex Hospital Mortality
dc.subject.otherIndex Hospitals, University
dc.subject.otherIndex Humans
dc.subject.otherIndex Hydroxymethylglutaryl-CoA Reductase Inhibitors
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Platelet Aggregation Inhibitors
dc.subject.otherIndex Registries
dc.subject.otherIndex Retrospective Studies
dc.subject.otherIndex Treatment Outcome
dc.subject.otherKeywordPlus
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