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Impact of nutrition on muscle mass, strength, and performance in older adults

Show simple item record Mithal A. Bonjour J.-P. Boonen S. Burckhardt P. Degens H. El Hajj Fuleihan G. Josse R. Lips P. Morales Torres J. Rizzoli R. Yoshimura N. Wahl D.A. Cooper C. Dawson-Hughes B.
dc.contributor.editor 2013 2017-10-05T15:40:13Z 2017-10-05T15:40:13Z 2013
dc.identifier 10.1007/s00198-012-2236-y
dc.description.abstract Muscle strength plays an important role in determining risk for falls, which result in fractures and other injuries. While bone loss has long been recognized as an inevitable consequence of aging, sarcopenia - the gradual loss of skeletal muscle mass and strength that occurs with advancing age - has recently received increased attention. A review of the literature was undertaken to identify nutritional factors that contribute to loss of muscle mass. The role of protein, acid-base balance, vitamin D-calcium, and other minor nutrients like B vitamins was reviewed. Muscle wasting is a multifactorial process involving intrinsic and extrinsic alterations. A loss of fast twitch fibers, glycation of proteins, and insulin resistance may play an important role in the loss of muscle strength and development of sarcopenia. Protein intake plays an integral part in muscle health and an intake of 1.0-1.2 g-kg of body weight per day is probably optimal for older adults. There is a moderate inverse relationship between vitamin D status and muscle strength. Chronic ingestion of acid-producing diets appears to have a negative impact on muscle performance, and decreases in vitamin B12 and folic acid intake may also impair muscle function through their action on homocysteine. An adequate nutritional intake and an optimal dietary acid-base balance are important elements of any strategy to preserve muscle mass and strength during aging. © 2012 International Osteoporosis Foundation and National Osteoporosis Foundation.
dc.format.extent Pages: (1555-1566)
dc.language English
dc.publisher LONDON
dc.relation.ispartof Publication Name: Osteoporosis International; Publication Year: 2013; Volume: 24; no. 5; Pages: (1555-1566);
dc.source Scopus
dc.title Impact of nutrition on muscle mass, strength, and performance in older adults
dc.type Review
dc.contributor.affiliation Mithal, A., Medanta Medicity, Gurgaon, India
dc.contributor.affiliation Bonjour, J.-P., Division of Bone Diseases, University Hospitals, Faculty of Medicine, Geneva, Switzerland
dc.contributor.affiliation Boonen, S., Centre for Metabolic Bone Diseases, Division of Geriatric Medicine, University of Leuven, Leuven, Belgium
dc.contributor.affiliation Burckhardt, P., Clinique Bois Cerf-Hirslanden, Lausanne, Switzerland
dc.contributor.affiliation Degens, H., Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, Manchester, United Kingdom, Division Space Physiology, Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany
dc.contributor.affiliation El Hajj Fuleihan, G., Calcium Metabolism and Osteoporosis Program, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Josse, R., Division of Endocrinology and Metabolism, University of Toronto, St. Michael's Hospital Health Centre, Toronto, Canada
dc.contributor.affiliation Lips, P., Division of Internal Medicine, Endocrine Section, VU University Medical Center, Amsterdam, Netherlands
dc.contributor.affiliation Morales Torres, J., Hospital Aranda de la Parra, Hidalgo-León, Mexico
dc.contributor.affiliation Rizzoli, R., Division of Bone Diseases, University Hospitals, Faculty of Medicine, Geneva, Switzerland
dc.contributor.affiliation Yoshimura, N., Department of Joint Disease Research, 22nd Century Medical and Research Center, University of Tokyo, Tokyo, Japan
dc.contributor.affiliation Wahl, D.A., International Osteoporosis Foundation, Nyon, Switzerland
dc.contributor.affiliation Cooper, C., MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom, NIHR Musculoskeletal Biomedical Research Unit, Institute of Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
dc.contributor.affiliation Dawson-Hughes, B., Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston MA, United States
dc.contributor.authorAddress Mithal, A.; Medanta Medicity, Gurgaon, India; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Mithal, A
dc.contributor.authorInitials Bonjour, JP
dc.contributor.authorInitials Boonen, S
dc.contributor.authorInitials Burckhardt, P
dc.contributor.authorInitials Degens, H
dc.contributor.authorInitials Fuleihan, GE
dc.contributor.authorInitials Josse, R
dc.contributor.authorInitials Lips, P
dc.contributor.authorInitials Torres, JM
dc.contributor.authorInitials Rizzoli, R
dc.contributor.authorInitials Yoshimura, N
dc.contributor.authorInitials Wahl, DA
dc.contributor.authorInitials Cooper, C
dc.contributor.authorInitials Dawson-Hughes, B
dc.contributor.authorReprintAddress Mithal, A (reprint author), Medanta Med, Sect 38, Gurgaon, India.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 20
dc.description.citedTotWOSCount 22
dc.description.citedWOSCount 20
dc.format.extentCount 12
dc.identifier.coden OSINE
dc.identifier.pubmedID 23247327
dc.identifier.scopusID 84881222191
dc.publisher.address 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND
dc.relation.ispartOfISOAbbr Osteoporosis Int.
dc.relation.ispartOfIssue 5
dc.relation.ispartofPubTitle Osteoporosis International
dc.relation.ispartofPubTitleAbbr Osteoporosis Int.
dc.relation.ispartOfVolume 24
dc.source.ID WOS:000318280100003
dc.type.publication Journal
dc.subject.otherAuthKeyword Aging
dc.subject.otherAuthKeyword IOF
dc.subject.otherAuthKeyword Malnutrition
dc.subject.otherAuthKeyword Muscle strength loss
dc.subject.otherAuthKeyword Nutritional
dc.subject.otherAuthKeyword Recommendations
dc.subject.otherAuthKeyword Sarcopenia
dc.subject.otherChemCAS calcium, 14092-94-5, 7440-70-2
dc.subject.otherChemCAS cyanocobalamin, 53570-76-6, 68-19-9, 8064-09-3
dc.subject.otherChemCAS folic acid, 59-30-3, 6484-89-5
dc.subject.otherChemCAS homocysteine, 454-28-4, 6027-13-0
dc.subject.otherChemCAS Dietary Proteins
dc.subject.otherChemCAS Vitamin D, 1406-16-2
dc.subject.otherIndex antiinflammatory agent
dc.subject.otherIndex antioxidant
dc.subject.otherIndex calcium
dc.subject.otherIndex cyanocobalamin
dc.subject.otherIndex folic acid
dc.subject.otherIndex homocysteine
dc.subject.otherIndex vitamin D
dc.subject.otherIndex acid base balance
dc.subject.otherIndex aging
dc.subject.otherIndex body weight
dc.subject.otherIndex diet supplementation
dc.subject.otherIndex fast muscle
dc.subject.otherIndex human
dc.subject.otherIndex insulin resistance
dc.subject.otherIndex muscle atrophy
dc.subject.otherIndex muscle function
dc.subject.otherIndex muscle mass
dc.subject.otherIndex muscle strength
dc.subject.otherIndex nutrition
dc.subject.otherIndex osteolysis
dc.subject.otherIndex priority journal
dc.subject.otherIndex protein function
dc.subject.otherIndex protein glycosylation
dc.subject.otherIndex protein intake
dc.subject.otherIndex review
dc.subject.otherIndex sarcopenia
dc.subject.otherIndex skeletal muscle
dc.subject.otherIndex vitamin intake
dc.subject.otherIndex Aged
dc.subject.otherIndex Aging
dc.subject.otherIndex Dietary Proteins
dc.subject.otherIndex Elder Nutritional Physiological Phenomena
dc.subject.otherIndex Humans
dc.subject.otherIndex Malnutrition
dc.subject.otherIndex Muscle Strength
dc.subject.otherIndex Nutritional Status
dc.subject.otherIndex Sarcopenia
dc.subject.otherIndex Vitamin D
dc.subject.otherKeywordPlus RANDOMIZED CONTROLLED-TRIAL
dc.subject.otherKeywordPlus VITAMIN-D STATUS
dc.subject.otherKeywordPlus CHRONIC METABOLIC-ACIDOSIS
dc.subject.otherKeywordPlus ESSENTIAL AMINO-ACIDS
dc.subject.otherKeywordPlus GROWTH-FACTOR-I
dc.subject.otherKeywordPlus SODIUM-BICARBONATE INGESTION
dc.subject.otherKeywordPlus HUMAN SKELETAL-MUSCLE
dc.subject.otherKeywordPlus CHRONIC-RENAL-FAILURE
dc.subject.otherKeywordPlus RESISTANCE EXERCISE
dc.subject.otherKeywordPlus PHYSICAL FUNCTION
dc.subject.otherWOS Endocrinology and Metabolism

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