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Association between hepatitis A virus and Helicobacter pylori in a developing country: The saga continues

Show simple item record Bizri A.R.N. Nuwayhid I.A. Hamadeh G.N. Steitieh S.W. Choukair A.M. Musharrafieh U.M.
dc.contributor.editor Oct-2006 2017-10-05T15:40:38Z 2017-10-05T15:40:38Z 2006
dc.identifier 10.1111/j.1440-1746.2006.04268.x
dc.identifier.issn 08159319
dc.description.abstract Background: The epidemiologic association between Helicobacter pylori and hepatitis A virus (HAV) has been evaluated by various different groups with conflicting conclusions. The aim of the present study was to determine the prevalence of HAV and H. pylori infection among adolescents attending high schools in Lebanon, and to identify the sociodemographic factors associated with their prevalence, individually and concurrently. Methods: Nine hundred and two school students 14-18 years of age were selected randomly from 30 schools scattered all over Lebanon and tested for IgG antibodies against hepatitis A and H. pylori. Each student received a copy of a self-administered questionnaire to be completed by his-her parents inquiring about demographics, history of immunization, and prior viral hepatitis illness in the student. Bivariate analysis examined the association between different sociodemographic variables and prior HAV or H. pylori infection, and multivariate regression analysis was done to determine the factors independently associated with prior infection. Results: Using ELISA the seroprevalence of antibodies against HAV was 71.3percent as compared to 61.6percent for anti-H. pylori. A total of 9.1percent of those tested were negative for both agents. A multinomial regression analysis revealed that place of residence in relation to district or urban versus rural areas, in addition to mothers' education, were important determinants for the incidence of both agents. Conclusion: The low number of subjects negative for both H. pylori and HAV antibodies in Lebanon is indicative of their high prevalence in the country. It is possible that this high prevalence reflects an age-specific prevalence rather than a true association. © 2006 The Authors.
dc.format.extent Pages: (1615-1621)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Journal of Gastroenterology and Hepatology (Australia); Publication Year: 2006; Volume: 21; no. 10; Pages: (1615-1621);
dc.source Scopus
dc.title Association between hepatitis A virus and Helicobacter pylori in a developing country: The saga continues
dc.type Article
dc.contributor.affiliation Bizri, A.R.N., Department of Internal Medicine, Division of Infectious Diseases, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Nuwayhid, I.A., Department of Family Medicine, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Hamadeh, G.N., Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Steitieh, S.W., Department of Epidemiology and Biostatistics, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Choukair, A.M., Department of Epidemiology and Biostatistics, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Musharrafieh, U.M., Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon, American University of Beirut Medical Center, PO Box 113-6044, Beirut, Lebanon
dc.contributor.authorAddress Musharrafieh, U.M.; American University of Beirut Medical Center, PO Box 113-6044, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine; Division: Infectious Diseases;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorDivision Infectious Diseases
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Bizri, ARN
dc.contributor.authorInitials Nuwayhid, IA
dc.contributor.authorInitials Hamadeh, GN
dc.contributor.authorInitials Steitieh, SW
dc.contributor.authorInitials Choukair, AM
dc.contributor.authorInitials Musharrafieh, UM
dc.contributor.authorReprintAddress Musharrafieh, UM (reprint author), Amer Univ Beirut, Med Ctr, Dept Internal Med, Div Infect Dis, POB 113-6044, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 7
dc.description.citedTotWOSCount 6
dc.description.citedWOSCount 6
dc.format.extentCount 7
dc.identifier.coden JGHEE
dc.identifier.pubmedID 16928226
dc.identifier.scopusID 33747615472
dc.publisher.address 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
dc.relation.ispartOfISOAbbr J. Gastroenterol. Hepatol.
dc.relation.ispartOfIssue 10
dc.relation.ispartofPubTitle Journal of Gastroenterology and Hepatology (Australia)
dc.relation.ispartofPubTitleAbbr J. Gastroenterol. Hepatol.
dc.relation.ispartOfVolume 21
dc.source.ID WOS:000239863300018
dc.type.publication Journal
dc.subject.otherAuthKeyword Epidemiology
dc.subject.otherAuthKeyword Helicobacter pylori
dc.subject.otherAuthKeyword Hepatitis A
dc.subject.otherAuthKeyword Serology
dc.subject.otherAuthKeyword Transmission
dc.subject.otherChemCAS Antibodies, Bacterial
dc.subject.otherChemCAS Antibodies, Viral
dc.subject.otherIndex immunoglobulin G antibody
dc.subject.otherIndex adolescent
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex demography
dc.subject.otherIndex developing country
dc.subject.otherIndex disease association
dc.subject.otherIndex education
dc.subject.otherIndex enzyme linked immunosorbent assay
dc.subject.otherIndex female
dc.subject.otherIndex Helicobacter infection
dc.subject.otherIndex Helicobacter pylori
dc.subject.otherIndex hepatitis A
dc.subject.otherIndex Hepatitis A virus
dc.subject.otherIndex human
dc.subject.otherIndex immunization
dc.subject.otherIndex Lebanon
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex priority journal
dc.subject.otherIndex seroprevalence
dc.subject.otherIndex superinfection
dc.subject.otherIndex urban rural difference
dc.subject.otherIndex virus hepatitis
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Antibodies, Bacterial
dc.subject.otherIndex Antibodies, Viral
dc.subject.otherIndex Enzyme-Linked Immunosorbent Assay
dc.subject.otherIndex Female
dc.subject.otherIndex Helicobacter Infections
dc.subject.otherIndex Helicobacter pylori
dc.subject.otherIndex Hepatitis A
dc.subject.otherIndex Hepatitis A virus
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Prevalence
dc.subject.otherIndex Questionnaires
dc.subject.otherIndex Risk Factors
dc.subject.otherKeywordPlus PEPTIC-ULCER DISEASE
dc.subject.otherKeywordPlus SOUTH-AFRICA
dc.subject.otherKeywordPlus INFECTION
dc.subject.otherKeywordPlus SEROPREVALENCE
dc.subject.otherKeywordPlus EPIDEMIOLOGY
dc.subject.otherKeywordPlus TRANSMISSION
dc.subject.otherKeywordPlus CHILDREN
dc.subject.otherKeywordPlus SEROEPIDEMIOLOGY
dc.subject.otherKeywordPlus NATAL-KWAZULU
dc.subject.otherKeywordPlus CHILDHOOD
dc.subject.otherWOS Gastroenterology and Hepatology

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