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Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy

Show simple item record Ayoub C. Skoury A. Abdul-Baki H. Nasr V. Soweid A.
dc.contributor.editor Oct-2007 2017-10-05T15:40:46Z 2017-10-05T15:40:46Z 2007
dc.identifier 10.1016/j.gie.2007.03.1086
dc.identifier.issn 00165107
dc.description.abstract Background: Conscious sedation is usually achieved during EGD by a combination of intravenous benzodiazepines and opiates; however, these have potential serious adverse effects. The addition of topical oropharyngeal anesthetics such as lidocaine may be useful. Recent data suggest that the administration of topical lidocaine by means of a lollipop is effective for endotracheal intubation and bronchoscopy. Objective: Our purpose was to evaluate the safety and efficacy of a lidocaine lollipop as single-agent anesthesia for EGD and to determine whether its use reduces the need for intravenous sedatives and analgesics. Design: Single-blinded, randomized, prospective study. Setting: University hospital. Patients: 50 patients undergoing diagnostic EGD. Interventions: Patients were randomized to either lidocaine lollipop or lidocaine spray. Intravenous meperidine and midazolam were administered during the procedure as needed. Main Outcome Measurements: The success and safety of local anesthesia by lidocaine lollipop in addition to the need for intravenous sedation. Results: Patients were equally randomized between the lollipop and the spray groups. The lollipop group had less gag reflex, accommodated scope introduction more, and tolerated the procedure better. Thirty-two percent of patients receiving the lollipop required sedation compared with 96percent of patients in the spray group (P .001). The majority in the lollipop group were satisfied with their mode of anesthesia compared with the spray group. Conclusions: Lidocaine lollipop is a promising form of local oropharyngeal anesthesia for EGD. Its use resulted in sparing the use of intravenous sedation. It is well tolerated and safe and may be particularly important in the elderly, patients with comorbidities, and office-based endoscopy. © 2007 American Society for Gastrointestinal Endoscopy.
dc.format.extent Pages: (786-793)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Gastrointestinal Endoscopy; Publication Year: 2007; Volume: 66; no. 4; Pages: (786-793);
dc.source Scopus
dc.title Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy
dc.type Article
dc.contributor.affiliation Ayoub, C., Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Skoury, A., Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Abdul-Baki, H., Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Nasr, V., Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Soweid, A., Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Skoury, A.; Current affiliations: Departments of Anesthesia (C. A., V. N.) and Internal Medicine (A. S., H. A-B., American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Internal Medicine;
dc.contributor.authorDepartment Internal Medicine
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Ayoub, C
dc.contributor.authorInitials Skoury, A
dc.contributor.authorInitials Abdul-Baki, H
dc.contributor.authorInitials Nasr, V
dc.contributor.authorInitials Soweid, A
dc.contributor.authorReprintAddress Soweid, A (reprint author), Amer Univ Beirut, Dept Internal Med, Med Ctr, POB 11-0236, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 13
dc.description.citedTotWOSCount 7
dc.description.citedWOSCount 6
dc.format.extentCount 8
dc.identifier.coden GAENB
dc.identifier.pubmedID 17905023
dc.identifier.scopusID 34648858625
dc.publisher.address 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
dc.relation.ispartOfISOAbbr Gastrointest. Endosc.
dc.relation.ispartOfIssue 4
dc.relation.ispartofPubTitle Gastrointestinal Endoscopy
dc.relation.ispartofPubTitleAbbr Gastrointest. Endosc.
dc.relation.ispartOfVolume 66
dc.source.ID WOS:000250166200024
dc.type.publication Journal
dc.subject.otherChemCAS lidocaine, 137-58-6, 24847-67-4, 56934-02-2, 73-78-9
dc.subject.otherChemCAS Anesthetics, Local
dc.subject.otherChemCAS Lidocaine, 137-58-6
dc.subject.otherIndex analgesic agent
dc.subject.otherIndex lidocaine
dc.subject.otherIndex sedative agent
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex clinical article
dc.subject.otherIndex clinical trial
dc.subject.otherIndex controlled clinical trial
dc.subject.otherIndex controlled study
dc.subject.otherIndex drug efficacy
dc.subject.otherIndex drug safety
dc.subject.otherIndex esophagogastroduodenoscopy
dc.subject.otherIndex female
dc.subject.otherIndex gastrointestinal endoscopy
dc.subject.otherIndex human
dc.subject.otherIndex local anesthesia
dc.subject.otherIndex male
dc.subject.otherIndex priority journal
dc.subject.otherIndex prospective study
dc.subject.otherIndex randomized controlled trial
dc.subject.otherIndex sedation
dc.subject.otherIndex university hospital
dc.subject.otherIndex Administration, Oral
dc.subject.otherIndex Administration, Topical
dc.subject.otherIndex Anesthetics, Local
dc.subject.otherIndex Conscious Sedation
dc.subject.otherIndex Dose-Response Relationship, Drug
dc.subject.otherIndex Endoscopy, Gastrointestinal
dc.subject.otherIndex Female
dc.subject.otherIndex Follow-Up Studies
dc.subject.otherIndex Gastrointestinal Diseases
dc.subject.otherIndex Humans
dc.subject.otherIndex Lidocaine
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Prospective Studies
dc.subject.otherIndex Single-Blind Method
dc.subject.otherKeywordPlus DOUBLE-BLIND
dc.subject.otherKeywordPlus CONTROLLED-TRIAL
dc.subject.otherKeywordPlus CONSCIOUS SEDATION
dc.subject.otherKeywordPlus RANDOMIZED-TRIAL
dc.subject.otherKeywordPlus CONVENTIONAL EGD
dc.subject.otherKeywordPlus TOLERANCE
dc.subject.otherKeywordPlus SAFETY
dc.subject.otherWOS Gastroenterology and Hepatology

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