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Pruritic urticarial papules and plaques of pregnancy: Epidemiological, clinical, and histopathological study of 18 cases from Lebanon

Show simple item record Ghazeeri G. Kibbi A.-G. Abbas O.
dc.contributor.editor Sep-2012 2017-10-05T15:46:52Z 2017-10-05T15:46:52Z 2012
dc.identifier 10.1111/j.1365-4632.2011.05203.x
dc.identifier.issn 00119059
dc.description.abstract Background Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a benign pruritic inflammatory skin disorder that usually affects primigravidae in their third trimester of pregnancy. Studies on this condition from our area are lacking. Objective and methods To describe the epidemiological, clinical, and histopathological findings of all patients diagnosed with PUPPP at the American University of Beirut Medical Center (AUB-MC) between 1998 and 2009 and compare our findings with those published in the literature. Results PUPPP mainly affected primigravidae (72percent) in the third trimester of pregnancy (89percent). Multiple gestation pregnancies were observed in 50percent of cases. The abdomen and proximal thighs were the most commonly involved sites (67percent), with exclusive involvement of the extremities in four cases. Although pruritic urticarial papules and plaques were the main morphological feature of PUPPP observed (98percent), five cases had additional features, and one case presented exclusively with papulovesicular lesions. Microscopically, all cases biopsied showed the typical features of PUPPP, including negative direct immunofluorescence findings. Emollients, topical corticosteroids, and-or oral antihistamines were generally adequate to control symptoms in all cases, in which skin lesions resolved in an average of three weeks. Conclusion This study showed a lower incidence of PUPPP in our population compared with its incidence in other populations. It also confirmed the previously described clinical features, benign course, and excellent outcome of the condition, although variations may occur. Significant associations mainly included multiple gestation pregnancies, excessive maternal weight, and Rh-positive blood type, while fetal gender and weight gain did not contribute. © 2012 The International Society of Dermatology.
dc.format.extent Pages: (1047-1053)
dc.language English
dc.publisher HOBOKEN
dc.relation.ispartof Publication Name: International Journal of Dermatology; Publication Year: 2012; Volume: 51; no. 9; Pages: (1047-1053);
dc.source Scopus
dc.title Pruritic urticarial papules and plaques of pregnancy: Epidemiological, clinical, and histopathological study of 18 cases from Lebanon
dc.type Article
dc.contributor.affiliation Ghazeeri, G., Departments of Obstetrics and Gynecology, American University of Beirut-Medical Center, Beirut, Lebanon
dc.contributor.affiliation Kibbi, A.-G., Departments of Dermatology, American University of Beirut-Medical Center, Beirut, Lebanon
dc.contributor.affiliation Abbas, O., Departments of Dermatology, American University of Beirut-Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Abbas, O.; Department of Dermatology, American University of Beirut Medical Center, Po Box 11-0236, Riad El Solh-Beirut, 1107 2020 Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Obstetrics and Gynecology;
dc.contributor.authorDepartment Obstetrics and Gynecology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Ghazeeri, G
dc.contributor.authorInitials Kibbi, AG
dc.contributor.authorInitials Abbas, O
dc.contributor.authorReprintAddress Abbas, O (reprint author), Amer Univ Beirut, Dept Dermatol, Med Ctr, POB 11-0236, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 1
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.format.extentCount 7
dc.identifier.coden IJDEB
dc.identifier.pubmedID 22909357
dc.identifier.scopusID 84865352792
dc.publisher.address 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
dc.relation.ispartOfISOAbbr Int. J. Dermatol.
dc.relation.ispartOfIssue 9
dc.relation.ispartofPubTitle International Journal of Dermatology
dc.relation.ispartofPubTitleAbbr Int. J. Dermatol.
dc.relation.ispartOfVolume 51
dc.source.ID WOS:000307891200004
dc.type.publication Journal
dc.subject.otherChemCAS Adrenal Cortex Hormones
dc.subject.otherChemCAS Emollients
dc.subject.otherChemCAS Histamine Antagonists
dc.subject.otherIndex antihistaminic agent
dc.subject.otherIndex corticosteroid
dc.subject.otherIndex emollient agent
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex clinical article
dc.subject.otherIndex corticosteroid therapy
dc.subject.otherIndex female
dc.subject.otherIndex histopathology
dc.subject.otherIndex human
dc.subject.otherIndex human tissue
dc.subject.otherIndex incidence
dc.subject.otherIndex Lebanon
dc.subject.otherIndex multiple pregnancy
dc.subject.otherIndex papular urticaria
dc.subject.otherIndex papulovesicular rash
dc.subject.otherIndex primigravida
dc.subject.otherIndex pruritic urticarial papule and plaque of pregnancy
dc.subject.otherIndex retrospective study
dc.subject.otherIndex skin pruritus
dc.subject.otherIndex third trimester pregnancy
dc.subject.otherIndex Administration, Cutaneous
dc.subject.otherIndex Adrenal Cortex Hormones
dc.subject.otherIndex Adult
dc.subject.otherIndex Emollients
dc.subject.otherIndex Female
dc.subject.otherIndex Fertilization in Vitro
dc.subject.otherIndex Gestational Age
dc.subject.otherIndex Histamine Antagonists
dc.subject.otherIndex Humans
dc.subject.otherIndex Incidence
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Parity
dc.subject.otherIndex Pregnancy
dc.subject.otherIndex Pregnancy Complications
dc.subject.otherIndex Pregnancy Trimester, Third
dc.subject.otherIndex Pregnancy, Triplet
dc.subject.otherIndex Pregnancy, Twin
dc.subject.otherIndex Pruritus
dc.subject.otherIndex Young Adult
dc.subject.otherKeywordPlus FETAL WEIGHT-GAIN
dc.subject.otherKeywordPlus POLYMORPHIC ERUPTION
dc.subject.otherKeywordPlus DERMATOSES
dc.subject.otherKeywordPlus GESTATIONIS
dc.subject.otherKeywordPlus DIAGNOSIS
dc.subject.otherWOS Dermatology

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