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Predictors of coronary artery disease in the Lebanese population

Show simple item record Abchee A. Puzantian H. Azar S.T. Shbaklo H. Nasrallah A. Sawaya F.J. Alam S. Zalloua P.A.
dc.contributor.editor May-2006 2017-10-05T15:46:56Z 2017-10-05T15:46:56Z 2006
dc.identifier 10.1016/j.thromres.2005.05.022
dc.identifier.issn 00493848
dc.description.abstract Background: Coronary artery disease (CAD) is one of the major causes of morbidity and mortality in the world. The disease is determined by many risk factors such as age, gender, diabetes, dyslipidemia, smoking, as well as elevated serum levels of lipoprotein (a) (Lp(a)), homocysteine, C-reactive protein (CRP) and uric acid. In this study, we evaluated the association of biologic and metabolic parameters with CAD in a group of Lebanese patients. Methods: Three hundred patients were recruited for the study. Biologic and blood metabolic parameters were measured. Patients were then divided into 3 groups according to their catheterization result: 0percent stenosis (controls), 50percent stenosis and ≥ 50percent stenosis. Results: Hyperlipidemias, CRP, homocysteine and uric acid levels in CAD patients were not different from those of the controls. However, age, elevated fasting blood glucose (FBG) and elevated serum Lp(a) levels were found to be strong independent predictors of CAD in our study population. Association with CAD was also shown for gender, hypertension, diabetes and family history of CAD. Conclusion: We report the importance of serum Lp(a) levels and FBG in the prediction and prevention of CAD in our population. © 2005 Elsevier Ltd. All rights reserved.
dc.format.extent Pages: (631-637)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Thrombosis Research; Publication Year: 2006; Volume: 117; no. 6; Pages: (631-637);
dc.source Scopus
dc.title Predictors of coronary artery disease in the Lebanese population
dc.type Article
dc.contributor.affiliation Abchee, A., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Puzantian, H., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Azar, S.T., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Shbaklo, H., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Nasrallah, A., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Sawaya, F.J., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Alam, S., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Zalloua, P.A., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon, Harvard School of Public Health, Boston, United States
dc.contributor.authorAddress Zalloua, P.A.; Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Obstetrics and Gynecology;
dc.contributor.authorDepartment Obstetrics and Gynecology
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Abchee, A
dc.contributor.authorInitials Puzantian, H
dc.contributor.authorInitials Azar, ST
dc.contributor.authorInitials Shbaklo, H
dc.contributor.authorInitials Nasrallah, A
dc.contributor.authorInitials Sawaya, FJ
dc.contributor.authorInitials Alam, S
dc.contributor.authorInitials Zalloua, PA
dc.contributor.authorReprintAddress Zalloua, PA (reprint author), Amer Univ Beirut, Dept Internal Med, Med Ctr, POB 11-0236, Beirut, Lebanon.
dc.contributor.authorResearcherID 王, 强-F-4212-2011
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 11
dc.description.citedTotWOSCount 8
dc.description.citedWOSCount 8
dc.format.extentCount 7
dc.identifier.coden THBRA
dc.identifier.pubmedID 15985286
dc.identifier.scopusID 33646075437
dc.relation.ispartOfISOAbbr Thromb. Res.
dc.relation.ispartOfIssue 6
dc.relation.ispartofPubTitle Thrombosis Research
dc.relation.ispartofPubTitleAbbr Thromb. Res.
dc.relation.ispartOfVolume 117
dc.source.ID WOS:000237369500004
dc.type.publication Journal
dc.subject.otherAuthKeyword Coronary artery disease
dc.subject.otherAuthKeyword Fasting blood glucose
dc.subject.otherAuthKeyword Lipoprotein (a)
dc.subject.otherChemCAS C reactive protein, 9007-41-4
dc.subject.otherChemCAS glucose, 50-99-7, 84778-64-3
dc.subject.otherChemCAS homocysteine, 454-28-4, 6027-13-0
dc.subject.otherChemCAS uric acid, 69-93-2
dc.subject.otherChemCAS Blood Glucose
dc.subject.otherChemCAS Lipoprotein(a)
dc.subject.otherIndex C reactive protein
dc.subject.otherIndex glucose
dc.subject.otherIndex homocysteine
dc.subject.otherIndex lipoprotein A
dc.subject.otherIndex uric acid
dc.subject.otherIndex adult
dc.subject.otherIndex age distribution
dc.subject.otherIndex aged
dc.subject.otherIndex amino acid blood level
dc.subject.otherIndex article
dc.subject.otherIndex cardiovascular risk
dc.subject.otherIndex controlled study
dc.subject.otherIndex coronary artery disease
dc.subject.otherIndex diabetes mellitus
dc.subject.otherIndex disease association
dc.subject.otherIndex family history
dc.subject.otherIndex female
dc.subject.otherIndex human
dc.subject.otherIndex hyperglycemia
dc.subject.otherIndex hyperlipidemia
dc.subject.otherIndex hypertension
dc.subject.otherIndex Lebanon
dc.subject.otherIndex lipoprotein blood level
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex prediction
dc.subject.otherIndex priority journal
dc.subject.otherIndex risk assessment
dc.subject.otherIndex sex difference
dc.subject.otherIndex uric acid blood level
dc.subject.otherIndex Aged
dc.subject.otherIndex Blood Glucose
dc.subject.otherIndex Case-Control Studies
dc.subject.otherIndex Coronary Angiography
dc.subject.otherIndex Coronary Arteriosclerosis
dc.subject.otherIndex Fasting
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Lipoprotein(a)
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Predictive Value of Tests
dc.subject.otherIndex Risk Factors
dc.subject.otherKeywordPlus CARDIOVASCULAR RISK-FACTORS
dc.subject.otherKeywordPlus SILENT-MYOCARDIAL-ISCHEMIA
dc.subject.otherKeywordPlus C-REACTIVE PROTEIN
dc.subject.otherKeywordPlus SERUM URIC-ACID
dc.subject.otherKeywordPlus HEART-DISEASE
dc.subject.otherKeywordPlus DIABETES-MELLITUS
dc.subject.otherKeywordPlus APOLIPOPROTEIN(A) PHENOTYPES
dc.subject.otherKeywordPlus LIPOPROTEIN(A) LEVELS
dc.subject.otherKeywordPlus PLASMA HOMOCYSTEINE
dc.subject.otherKeywordPlus VASCULAR-DISEASE
dc.subject.otherWOS Hematology
dc.subject.otherWOS Peripheral Vascular Disease

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