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Effect of 17α-hydroxyprogesterone caproate before embryo transfer on the outcome of in vitro fertilization and embryo transfer: a randomized trial

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dc.contributor.author Abu-Musa A.
dc.contributor.author Usta I.
dc.contributor.author Nassar A.
dc.contributor.author Hajami F.
dc.contributor.author Hannoun A.
dc.contributor.editor
dc.date May-2008
dc.date.accessioned 2017-10-05T15:47:03Z
dc.date.available 2017-10-05T15:47:03Z
dc.date.issued 2008
dc.identifier 10.1016/j.fertnstert.2007.05.043
dc.identifier.isbn
dc.identifier.issn 00150282
dc.identifier.uri http://hdl.handle.net/10938/18611
dc.description.abstract Objective: To assess the effect of 17α-hydroxyprogesterone caproate (17-HPC) given before embryo transfer on the pregnancy outcome of IVF-embryo transfer (ET) cycles. Design: Randomized controlled study. Setting: A university-based hospital IVF unit. Patient(s): One hundred twenty-five consecutive patients undergoing IVF-ET were randomly assigned into treatment and control groups. Intervention(s): In the treatment group, 63 patients received 17-HPC (250 mg, IM), 1 day before ET. The control group consisted of 62 patients who did not receive any injections. Main Outcome Measure(s): Pregnancy and multiple-pregnancy rates. Result(s): The two groups were similar with respect to the age of patients, total dose of FSH, number of oocytes and embryos obtained, and number and quality of embryos transferred. There was no significant difference in the pregnancy rate (34.9percent vs. 38.7percent) or in the rate of multiple gestation (15.9percent vs. 9.7percent) between cases and controls, respectively. Conclusion(s): The use of 17-HPC before ET does not appear to affect the outcome of IVF-ET. © 2008 American Society for Reproductive Medicine.
dc.format.extent
dc.format.extent Pages: (1098-1102)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Fertility and Sterility; Publication Year: 2008; Volume: 89; no. 5; Pages: (1098-1102);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Effect of 17α-hydroxyprogesterone caproate before embryo transfer on the outcome of in vitro fertilization and embryo transfer: a randomized trial
dc.type Article
dc.contributor.affiliation Abu-Musa, A., Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Usta, I., Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Nassar, A., Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Hajami, F., Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Hannoun, A., Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Abu-Musa, A.; Department of Obstetrics and Gynecology, American University, Beirut Medical Center, Beirut, Lebanon; email: aa06@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Obstetrics and Gynecology;
dc.contributor.authorDepartment Obstetrics and Gynecology
dc.contributor.authorDivision
dc.contributor.authorEmail aa06@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Abu-Musa, A
dc.contributor.authorInitials Usta, I
dc.contributor.authorInitials Nassar, A
dc.contributor.authorInitials Hajami, F
dc.contributor.authorInitials Hannoun, A
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Abu-Musa, A (reprint author), Amer Univ Beirut, Med Ctr, Dept Obstet and Gynecol, POB 113-6044-6A, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Abate A, 1999, GYNECOL OBSTET INVES, V48, P78, DOI 10.1159-000010143; ABRAMOWICZ JS, 1990, FERTIL STERIL, V54, P451; Ayoubi JM, 2001, FERTIL STERIL, V76, P736, DOI 10.1016-S0015-0282(01)01998-7; BULLETTI C, 1993, HUM REPROD, V8, P1558; Costabile L, 2001, FERTIL STERIL, V76, P394, DOI 10.1016-S0015-0282(01)01901-X; DAWOOD MY, 1993, AM J OBSTET GYNECOL, V169, P1255; Fanchin R, 2000, FERTIL STERIL, V74, P274, DOI 10.1016-S0015-0282(00)00643-9; Fanchin R, 1998, HUM REPROD, V13, P1968, DOI 10.1093-humrep-13.7.1968; Fanchin R, 2001, FERTIL STERIL, V75, P1136, DOI 10.1016-S0015-0282(01)01787-3; Fanchin R, 2000, HUM REPROD, V15, P90; Ijland MM, 1996, FERTIL STERIL, V65, P746; Ijland MM, 1998, FERTIL STERIL, V70, P279, DOI 10.1016-S0015-0282(98)00132-0; Ijland MM, 1997, FERTIL STERIL, V67, P492, DOI 10.1016-S0015-0282(97)80075-1; LEETON J, 1985, Journal of In Vitro Fertilization and Embryo Transfer, V2, P166, DOI 10.1007-BF01131506; Leyendecker G, 1996, HUM REPROD, V11, P1542; LYONS EA, 1991, FERTIL STERIL, V55, P771; Moon HS, 2004, FERTIL STERIL, V82, P816, DOI 10.1016-j.fertnstert.2004.02.140; OIKE K, 1988, J ULTRAS MED, V7, pS99; ONSRUD M, 1985, ACTA OBSTET GYN SCAN, V64, P519; SALAMANCA A, 1995, FERTIL STERIL, V64, P193; STEER CV, 1992, HUM REPROD, V7, P117; TABIBZADEH S, 1995, HUM REPROD, V10, P1579; The Rotterdam ESHRE-ASRM-Sponsored PCOS Consensus Workshop Group, 2004, HUMAN REPROD, V19, P41, DOI [10.1093-humrep-deh098, DOI 10.1093-HUMREP-DEH098]; Unfer V, 2004, REPROD BIOMED ONLINE, V9, P17; World Health Organization, 1999, WHO LAB MAN EX HUM S; Zaidi J, 1996, FERTIL STERIL, V65, P377
dc.description.citedCount
dc.description.citedTotWOSCount 2
dc.description.citedWOSCount 2
dc.format.extentCount 5
dc.identifier.articleNo
dc.identifier.coden FESTA
dc.identifier.pubmedID 17658525
dc.identifier.scopusID 43649091959
dc.identifier.url
dc.publisher.address 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
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dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Fertil. Steril.
dc.relation.ispartOfIssue 5
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Fertility and Sterility
dc.relation.ispartofPubTitleAbbr Fertil. Steril.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 89
dc.source.ID WOS:000256075700011
dc.type.publication Journal
dc.subject.otherAuthKeyword 17α-hydroxyprogesterone caproate
dc.subject.otherAuthKeyword IVF-ET
dc.subject.otherAuthKeyword pregnancy outcome
dc.subject.otherChemCAS hydroxyprogesterone caproate, 630-56-8
dc.subject.otherChemCAS 17-alpha-hydroxy-progesterone caproate, 630-56-8
dc.subject.otherChemCAS Hydroxyprogesterones
dc.subject.otherChemCAS Progestins
dc.subject.otherIndex hydroxyprogesterone caproate
dc.subject.otherIndex 17-alpha-hydroxy-progesterone caproate
dc.subject.otherIndex gestagen
dc.subject.otherIndex hydroxyprogesterone caproate
dc.subject.otherIndex progesterone derivative
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex clinical trial
dc.subject.otherIndex controlled clinical trial
dc.subject.otherIndex controlled study
dc.subject.otherIndex drug effect
dc.subject.otherIndex embryo transfer
dc.subject.otherIndex female
dc.subject.otherIndex fertilization in vitro
dc.subject.otherIndex human
dc.subject.otherIndex major clinical study
dc.subject.otherIndex multivariate logistic regression analysis
dc.subject.otherIndex outcome assessment
dc.subject.otherIndex pregnancy
dc.subject.otherIndex pregnancy outcome
dc.subject.otherIndex priority journal
dc.subject.otherIndex randomized controlled trial
dc.subject.otherIndex embryo transfer
dc.subject.otherIndex fertilization in vitro
dc.subject.otherIndex methodology
dc.subject.otherIndex middle aged
dc.subject.otherIndex pregnancy outcome
dc.subject.otherIndex pregnancy rate
dc.subject.otherIndex smooth muscle
dc.subject.otherIndex uterus
dc.subject.otherIndex Adult
dc.subject.otherIndex Embryo Transfer
dc.subject.otherIndex Female
dc.subject.otherIndex Fertilization in Vitro
dc.subject.otherIndex Humans
dc.subject.otherIndex Hydroxyprogesterones
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Muscle, Smooth
dc.subject.otherIndex Pregnancy
dc.subject.otherIndex Pregnancy Outcome
dc.subject.otherIndex Pregnancy Rate
dc.subject.otherIndex Progestins
dc.subject.otherIndex Uterus
dc.subject.otherKeywordPlus WAVE-LIKE ACTIVITY
dc.subject.otherKeywordPlus UTERINE CONTRACTILITY
dc.subject.otherKeywordPlus VAGINAL PROGESTERONE
dc.subject.otherKeywordPlus MENSTRUAL-CYCLE
dc.subject.otherKeywordPlus ULTRASOUND
dc.subject.otherKeywordPlus ENDOMETRIOSIS
dc.subject.otherKeywordPlus PROGRAM
dc.subject.otherKeywordPlus TIME
dc.subject.otherWOS Obstetrics and Gynecology
dc.subject.otherWOS Reproductive Biology


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