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Attitude of women with IVF and spontaneous pregnancies towards prenatal screening

Show simple item record Abu-Musa A.A. Nassar A.H. Usta I.M.
dc.contributor.editor Nov-2008 2017-10-05T15:47:05Z 2017-10-05T15:47:05Z 2008
dc.identifier 10.1093/humrep/den291
dc.identifier.issn 02681161
dc.description.abstract BACKGROUND: Factors influencing a pregnant woman's decision to accept prenatal testing are largely undefined. Our study aimed to compare the acceptance rate of prenatal diagnosis in women who conceived through IVF or ICSI (cases) with that of women who conceived spontaneously (controls). METHODS: Retrospective chart review in Lebanon of all primiparas carrying singletons who were offered prenatal testing (triple screen-amniocentesis) from 2004-2007. The influence of IVF-ICSI on the acceptance of prenatal screening was evaluated. RESULTS: 336 pregnant women were offered prenatal testing (120 cases and 216 controls). Cases were less likely to perform prenatal testing compared with controls (52.5 versus 72.7percent; P 0.001). The rate of utilization of prenatal testing was independent of the infertility cause. Multiple logistic regression analysis revealed that women who conceived through IVF-ICSI [odds ratio (OR) 0.427, 95percent confidence interval (CI) 0.252-0.724], those ≥35 years old (OR 0.184, 95percent CI 0.102-0.329) and lower socioeconomic class (OR 0.339, 95percent CI 0.197-0.584) were less likely to perform triple screen test, and women who conceived through IVF-ICSI (OR 0.354, 95percent CI 0.131-0.958) and those of lower socioeconomic class (OR 0.113, 95percent CI 0.033-0.403) were less likely to perform amniocentesis. CONCLUSIONS: There was a significant difference in acceptance rate of prenatal diagnostic testing between women who conceived through IVF-ICSI and those who conceived spontaneously. Women who conceived through IVF-ICSI were less likely to opt for prenatal diagnosis even after controlling for confounding variables. © The Author 2008. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.
dc.format.extent Pages: (2438-2443)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Human Reproduction; Publication Year: 2008; Volume: 23; no. 11; Pages: (2438-2443);
dc.source Scopus
dc.title Attitude of women with IVF and spontaneous pregnancies towards prenatal screening
dc.type Article
dc.contributor.affiliation Abu-Musa, A.A., Department of Obstetrics and Gynecology, American University of Beirut Medical Center, PO Box: 113-6044-6A, Beirut, Lebanon
dc.contributor.affiliation Nassar, A.H., Department of Obstetrics and Gynecology, American University of Beirut Medical Center, PO Box: 113-6044-6A, Beirut, Lebanon
dc.contributor.affiliation Usta, I.M., Department of Obstetrics and Gynecology, American University of Beirut Medical Center, PO Box: 113-6044-6A, Beirut, Lebanon
dc.contributor.authorAddress Abu-Musa, A. A.; Department of Obstetrics and Gynecology, American University of Beirut Medical Center, PO Box: 113-6044-6A, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Obstetrics and Gynecology;
dc.contributor.authorDepartment Obstetrics and Gynecology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Abu-Musa, AA
dc.contributor.authorInitials Nassar, AH
dc.contributor.authorInitials Usta, IM
dc.contributor.authorReprintAddress Abu-Musa, AA (reprint author), Amer Univ Beirut, Med Ctr, Dept Obstet and Gynecol, POB 113-6044-6A, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 5
dc.description.citedTotWOSCount 5
dc.description.citedWOSCount 5
dc.format.extentCount 6
dc.identifier.coden HUREE
dc.identifier.pubmedID 18664471
dc.identifier.scopusID 54149095979
dc.relation.ispartOfISOAbbr Hum. Reprod.
dc.relation.ispartOfIssue 11
dc.relation.ispartofPubTitle Human Reproduction
dc.relation.ispartofPubTitleAbbr Hum. Reprod.
dc.relation.ispartOfVolume 23
dc.source.ID WOS:000260142900006
dc.type.publication Journal
dc.subject.otherAuthKeyword Amniocentesis
dc.subject.otherAuthKeyword IVF
dc.subject.otherAuthKeyword Spontaneous pregnancy
dc.subject.otherAuthKeyword Triple screen
dc.subject.otherIndex acceptance
dc.subject.otherIndex adult
dc.subject.otherIndex amniocentesis
dc.subject.otherIndex anxiety
dc.subject.otherIndex article
dc.subject.otherIndex attitude to pregnancy
dc.subject.otherIndex behavior
dc.subject.otherIndex chi square test
dc.subject.otherIndex confidence interval
dc.subject.otherIndex controlled study
dc.subject.otherIndex female
dc.subject.otherIndex fertilization in vitro
dc.subject.otherIndex financial management
dc.subject.otherIndex human
dc.subject.otherIndex infertility
dc.subject.otherIndex intracytoplasmic sperm injection
dc.subject.otherIndex Lebanon
dc.subject.otherIndex logistic regression analysis
dc.subject.otherIndex medical record review
dc.subject.otherIndex multivariate logistic regression analysis
dc.subject.otherIndex parthenogenesis
dc.subject.otherIndex pregnant woman
dc.subject.otherIndex prenatal screening
dc.subject.otherIndex primipara
dc.subject.otherIndex religion
dc.subject.otherIndex retrospective study
dc.subject.otherIndex socioeconomics
dc.subject.otherIndex Student t test
dc.subject.otherIndex Adult
dc.subject.otherIndex Amniocentesis
dc.subject.otherIndex Attitude to Health
dc.subject.otherIndex Case-Control Studies
dc.subject.otherIndex Female
dc.subject.otherIndex Fertilization in Vitro
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Odds Ratio
dc.subject.otherIndex Pregnancy
dc.subject.otherIndex Prenatal Diagnosis
dc.subject.otherIndex Regression Analysis
dc.subject.otherIndex Retrospective Studies
dc.subject.otherIndex Social Class
dc.subject.otherIndex Sperm Injections, Intracytoplasmic
dc.subject.otherKeywordPlus IN-VITRO FERTILIZATION
dc.subject.otherKeywordPlus REPRODUCTIVE TECHNOLOGIES
dc.subject.otherKeywordPlus LEBANON
dc.subject.otherKeywordPlus AMNIOCENTESIS
dc.subject.otherKeywordPlus COUPLES
dc.subject.otherKeywordPlus RISK
dc.subject.otherKeywordPlus PREFERENCES
dc.subject.otherKeywordPlus ACCEPTANCE
dc.subject.otherWOS Obstetrics and Gynecology
dc.subject.otherWOS Reproductive Biology

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