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Intrastromal corneal ring segment SK for moderate to severe keratoconus: A case series

Show simple item record Fahd D.C. Jabbur N.S. Awwad S.T.
dc.contributor.editor Oct-2012 2017-10-05T15:49:22Z 2017-10-05T15:49:22Z 2012
dc.identifier 10.3928/1081597X-20120921-05
dc.description.abstract PURPOSE: To report clinical results and safety profiles of symmetrical intrastromal corneal ring segment (ICRS; Intacs SK, Addition Technology Inc) implantation in eyes with moderate to severe keratoconus. METHODS: Interventional case series of 24 eyes from 22 patients implanted with Intacs SK using the femtosecond laser. Evaluation included uncorrected (UDVA) and corrected distance visual acuity (CDVA), manifest refraction, and Placido-based Scheimpflug imaging. Postoperative follow-up was 1 day, 1 week, and 1, 3, and 6 months. RESULTS: Mean patient age was 28±7 years (range: 16 to 41 years). All eyes had keratoconus. Twenty-one of 24 eyes had 2, 450-μm symmetrical segments inserted. Mean UDVA and CDVA were significantly better at 1, 3, and 6 months postoperatively (UDVA: 20-340 preoperatively vs 20-70 at 6 months [P.001]; CDVA: 20-70 preoperatively vs 20-40 at 6 months [P.001]; UDVA analysis of variance [ANOVA]: F=6.46, P=.0057; CDVA ANOVA: F=5.24, P=.0138). Pre- and 6-months postoperative clinical results were: mean spherical equivalent refractive error -9.60±4.86 diopters (D) and -3.05±2.05 D (P.001), respectively; mean refractive cylinder, -3.20±1.50 D and -1.55±1.10 D, respectively (P.001); and mean average total corneal power 52.03±4.49 D and 46.95±4.61 D, respectively (P.001). No complications occurred, and no patients were lost to follow-up. Eyes with steeper preoperative corneal keratometry readings had the greatest flattening in corneal curvature and thus the greatest decrease in myopic refraction (r=-0.4, P.001). No correlation was found between preoperative thinnest corneal pachymetry and postoperative curvature flattening. CONCLUSIONS: Implantation of Intacs SK for moderate to severe keratoconus is safe and effective, leading to significant decrease in myopia and appreciable decrease in astigmatism with improvement in CDVA.
dc.format.extent Pages: (701-705)
dc.language English
dc.publisher THOROFARE
dc.relation.ispartof Publication Name: Journal of Refractive Surgery; Publication Year: 2012; Volume: 28; no. 10; Pages: (701-705);
dc.source Scopus
dc.title Intrastromal corneal ring segment SK for moderate to severe keratoconus: A case series
dc.type Article
dc.contributor.affiliation Fahd, D.C., Dept. of Ophthalmology, American University of Beirut Medical Center, Cairo St, Beirut 01-350000, Lebanon
dc.contributor.affiliation Jabbur, N.S., Dept. of Ophthalmology, American University of Beirut Medical Center, Cairo St, Beirut 01-350000, Lebanon, Laser Center of Clemenceau Medical Center, Beirut, Lebanon
dc.contributor.affiliation Awwad, S.T., Dept. of Ophthalmology, American University of Beirut Medical Center, Cairo St, Beirut 01-350000, Lebanon
dc.contributor.authorAddress Awwad, S.T.; Dept. of Ophthalmology, American University of Beirut Medical Center, Cairo St, Beirut 01-350000, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Ophthalmology;
dc.contributor.authorDepartment Ophthalmology
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Fahd, DC
dc.contributor.authorInitials Jabbur, NS
dc.contributor.authorInitials Awwad, ST
dc.contributor.authorReprintAddress Awwad, ST (reprint author), Amer Univ Beirut, Dept Ophthalmol, Med Ctr, Cairo St, Beirut 01350000, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Alio JL, 2006, J CATARACT REFR SURG, V32, P978, DOI 10.1016-j.jcrs.2006.02.044; [Anonymous], 2009, INT PRESURGICAL PLAN; Colin J, 2000, J CATARACT REFR SURG, V26, P1117, DOI 10.1016-S0886-3350(00)00451-X; Ertan A, 2006, J CATARACT REFR SURG, V32, P2039, DOI 10.1016-j.jcrs.2006.08.032; Kanellopoulos AJ, 2006, CORNEA, V25, P29, DOI 10.1097-01.ico.0000167883.63266.60; Kaya V, 2011, J REFRACT SURG, V27, P907, DOI 10.3928-1081597X-20110906-03; Khan MI, 2012, J CATARACT REFR SURG, V38, P129, DOI 10.1016-j.jcrs.2011.07.031; Krumeich JH, 1997, KLIN MONATSBL AUGENH, V211, P94, DOI 10.1055-s-2008-1035103; Kymionis GD, 2010, CORNEA, V29, P214, DOI 10.1097-ICO.0b013e3181a26b72; Rabinowitz Yaron S, 2010, Int Ophthalmol Clin, V50, P63, DOI 10.1097-IIO.0b013e3181e21b76; Sansanayudh W, 2010, J CATARACT REFR SURG, V36, P110, DOI 10.1016-j.jcrs.2009.07.040; Zare MA, 2007, J CATARACT REFR SURG, V33, P1886, DOI 10.1016-j.jcrs.2007.06.055
dc.description.citedCount 1
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.format.extentCount 5
dc.identifier.coden JRSUF
dc.identifier.pubmedID 23062000
dc.identifier.scopusID 84870174163
dc.publisher.address 6900 GROVE RD, THOROFARE, NJ 08086 USA
dc.relation.ispartOfISOAbbr J. Refractive Surg.
dc.relation.ispartOfIssue 10
dc.relation.ispartofPubTitle Journal of Refractive Surgery
dc.relation.ispartofPubTitleAbbr J. Refractive Surg.
dc.relation.ispartOfVolume 28
dc.source.ID WOS:000314515700007
dc.type.publication Journal
dc.subject.otherIndex adolescent
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex astigmatism
dc.subject.otherIndex clinical article
dc.subject.otherIndex cornea curvature
dc.subject.otherIndex cornea power
dc.subject.otherIndex cornea thickness
dc.subject.otherIndex corrected distance visual acuity
dc.subject.otherIndex diagnostic imaging
dc.subject.otherIndex disease severity
dc.subject.otherIndex eye refraction
dc.subject.otherIndex female
dc.subject.otherIndex femtosecond laser
dc.subject.otherIndex follow up
dc.subject.otherIndex human
dc.subject.otherIndex intrastromal corneal ring segment
dc.subject.otherIndex keratoconus
dc.subject.otherIndex keratometry
dc.subject.otherIndex male
dc.subject.otherIndex myopia
dc.subject.otherIndex preoperative evaluation
dc.subject.otherIndex priority journal
dc.subject.otherIndex refraction error
dc.subject.otherIndex risk assessment
dc.subject.otherIndex treatment outcome
dc.subject.otherIndex uncorrected distance visual acuity
dc.subject.otherIndex visual acuity
dc.subject.otherIndex visual system parameters
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Corneal Pachymetry
dc.subject.otherIndex Corneal Stroma
dc.subject.otherIndex Corneal Topography
dc.subject.otherIndex Female
dc.subject.otherIndex Follow-Up Studies
dc.subject.otherIndex Humans
dc.subject.otherIndex Keratoconus
dc.subject.otherIndex Male
dc.subject.otherIndex Prostheses and Implants
dc.subject.otherIndex Prosthesis Implantation
dc.subject.otherIndex Refractive Errors
dc.subject.otherIndex Visual Acuity
dc.subject.otherIndex Young Adult
dc.subject.otherKeywordPlus IMPLANTATION
dc.subject.otherKeywordPlus INTACS
dc.subject.otherKeywordPlus MANAGEMENT
dc.subject.otherKeywordPlus EFFICACY
dc.subject.otherKeywordPlus LASER
dc.subject.otherWOS Ophthalmology
dc.subject.otherWOS Surgery

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