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Intravitreal bevacizumab for consecutive multiple choroidal breast metastatic lesions

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dc.contributor.author Mansour A.M.
dc.contributor.author Alameddine R.
dc.contributor.editor
dc.date 2012
dc.date.accessioned 2017-10-05T15:49:23Z
dc.date.available 2017-10-05T15:49:23Z
dc.date.issued 2012
dc.identifier 10.1136/bcr.03.2012.6124
dc.identifier.isbn
dc.identifier.issn
dc.identifier.uri http://hdl.handle.net/10938/18835
dc.description.abstract A 49-year-old woman presented with visual loss in the right from optic nerve metastatic disease and asymptomatic choroidal lesion at the inferior arcade. Throughout 22 months of follow-up, she developed a total of fi ve different sequential choroidal metastases to the left eye that were non-responsive to chemotherapy but showed prompt tumour regression by fundus examination and fl uorescein angiography within 2 weeks after a single intravitreal bevacizumab. The control of the lesion with a single intravitreal injection of bevacizumab refl ects the superior choroidal bioavailability of the drug. The persistence of subretinal fl uid at the site of prior metastases may be thought to be one sign of persistence of malignant cells, but in the current case and in the literature, it seems a refl ection of a diseased retinal pigment epithelium with probable damage from the tumour invasion. Copyright 2012 BMJ Publishing Group. All rights reserved.
dc.format.extent
dc.language English
dc.relation.ispartof Publication Name: BMJ Case Reports; Publication Year: 2012;
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Intravitreal bevacizumab for consecutive multiple choroidal breast metastatic lesions
dc.type Article
dc.contributor.affiliation Mansour, A.M., Ophthalmology Department, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Alameddine, R., Ophthalmology Department, American University of Beirut, Beirut, Lebanon
dc.contributor.authorAddress Mansour, A.M.; Ophthalmology Department, American University of Beirut, Beirut, Lebanon; email: ammansourmd@gmail.com
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Ophthalmology;
dc.contributor.authorDepartment Ophthalmology
dc.contributor.authorDivision
dc.contributor.authorEmail
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited
dc.description.citedCount 1
dc.description.citedTotWOSCount
dc.description.citedWOSCount
dc.format.extentCount 1
dc.identifier.articleNo
dc.identifier.coden
dc.identifier.pubmedID
dc.identifier.scopusID 84864587800
dc.identifier.url
dc.publisher.address
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr
dc.relation.ispartOfIssue
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle BMJ Case Reports
dc.relation.ispartofPubTitleAbbr BMJ Case Rep.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume
dc.source.ID
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS bevacizumab, 216974-75-3
dc.subject.otherChemCAS capecitabine, 154361-50-9
dc.subject.otherChemCAS cisplatin, 15663-27-1, 26035-31-4, 96081-74-2
dc.subject.otherChemCAS gemcitabine, 103882-84-4
dc.subject.otherChemCAS paclitaxel, 33069-62-4
dc.subject.otherChemCAS tamoxifen, 10540-29-1
dc.subject.otherIndex bevacizumab
dc.subject.otherIndex capecitabine
dc.subject.otherIndex cisplatin
dc.subject.otherIndex gemcitabine
dc.subject.otherIndex paclitaxel
dc.subject.otherIndex tamoxifen
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex bone metastasis
dc.subject.otherIndex brain metastasis
dc.subject.otherIndex breast cancer
dc.subject.otherIndex cancer radiotherapy
dc.subject.otherIndex cancer regression
dc.subject.otherIndex case report
dc.subject.otherIndex choroid cancer
dc.subject.otherIndex choroid disease
dc.subject.otherIndex choroid metastasis
dc.subject.otherIndex drug treatment failure
dc.subject.otherIndex female
dc.subject.otherIndex fluorescence angiography
dc.subject.otherIndex follow up
dc.subject.otherIndex human
dc.subject.otherIndex lung metastasis
dc.subject.otherIndex lymph node dissection
dc.subject.otherIndex mastectomy
dc.subject.otherIndex multiple cycle treatment
dc.subject.otherIndex off label drug use
dc.subject.otherIndex ophthalmoscopy
dc.subject.otherIndex optic nerve atrophy
dc.subject.otherIndex optic nerve disease
dc.subject.otherIndex priority journal
dc.subject.otherIndex skin metastasis
dc.subject.otherIndex treatment outcome
dc.subject.otherIndex visual impairment
dc.subject.otherIndex visual system examination
dc.subject.otherKeywordPlus
dc.subject.otherWOS


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