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Imaging characteristics of children with auditory neuropathy spectrum disorder

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dc.contributor.author Roche J.P.
dc.contributor.author Huang B.Y.
dc.contributor.author Castillo M.
dc.contributor.author Bassim M.K.
dc.contributor.author Adunka O.F.
dc.contributor.author Buchman C.A.
dc.contributor.editor
dc.date Jul-2010
dc.date.accessioned 2017-10-05T15:50:31Z
dc.date.available 2017-10-05T15:50:31Z
dc.date.issued 2010
dc.identifier 10.1097/MAO.0b013e3181d8d528
dc.identifier.isbn
dc.identifier.issn 15317129
dc.identifier.uri http://hdl.handle.net/10938/18910
dc.description.abstract OBJECTI*E:: To identify and define the imaging characteristics of children with auditory neuropathy spectrum disorder (ANSD). DESIGN:: Retrospective medical records review and analysis of both temporal bone computed tomographic (CT) and magnetic resonance images (MRI) in children with a diagnosis of ANSD. SETTING:: Tertiary referral center. PATIENTS:: One hundred eighteen children with the electrophysiologic characteristics of ANSD with available imaging studies for review. INTERVENTIONS:: Two neuroradiologists and a neurotologist reviewed each study, and consensus descriptions were established. MAIN OUTCOME MEASURES:: The type and number of imaging findings were tabulated. RESULTS:: Sixty-eight (64percent) MRIs revealed at least 1 imaging abnormality, whereas selective use of CT identified 23 (55percent) with anomalies. The most prevalent MRI findings included cochlear nerve deficiency (n = 51; 28percent of 183 nerves), brain abnormalities (n = 42; 40percent of 106 brains), and prominent temporal horns (n = 33, 16percent of 212 temporal lobes). The most prevalent CT finding from selective use of CT was cochlear dysplasia (n = 13; 31percent). CONCLUSION:: Magnetic resonance imaging will identify many abnormalities in children with ANSD that are not readily discernable on CT. Specifically, both developmental and acquired abnormalities of the brain, posterior cranial fossa, and cochlear nerves are not uncommonly seen in this patient population. Inner ear anomalies are well delineated using either imaging modality. Because many of the central nervous system findings identified in this study using MRI can alter the treatment and prognosis for these children, we think that MRI should be the initial imaging study of choice for children with ANSD. Copyright © 2010 Otology and Neurotology, Inc.
dc.format.extent
dc.format.extent Pages: (780-788)
dc.language English
dc.publisher PHILADELPHIA
dc.relation.ispartof Publication Name: Otology and Neurotology; Publication Year: 2010; Volume: 31; no. 5; Pages: (780-788);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Imaging characteristics of children with auditory neuropathy spectrum disorder
dc.type Article
dc.contributor.affiliation Roche, J.P., Department of Otolaryngology-Head and Neck Surgery, Physician's Office Building, CB 7070, 170 Manning Drive, Chapel Hill, NC 27599-7070, United States
dc.contributor.affiliation Huang, B.Y., Departmetn of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
dc.contributor.affiliation Castillo, M., Departmetn of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
dc.contributor.affiliation Bassim, M.K., Department of Otolaryngology-Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Adunka, O.F., Department of Otolaryngology-Head and Neck Surgery, Physician's Office Building, CB 7070, 170 Manning Drive, Chapel Hill, NC 27599-7070, United States
dc.contributor.affiliation Buchman, C.A., Department of Otolaryngology-Head and Neck Surgery, Physician's Office Building, CB 7070, 170 Manning Drive, Chapel Hill, NC 27599-7070, United States
dc.contributor.authorAddress Buchman, C. A.; Department of Otolaryngology-Head and Neck Surgery, Physician's Office Building, CB 7070, 170 Manning Drive, Chapel Hill, NC 27599-7070, United States; email: buchman@med.unc.edu
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Otolaryngology;
dc.contributor.authorDepartment Otolaryngology
dc.contributor.authorDivision
dc.contributor.authorEmail buchman@med.unc.edu
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Roche, JP
dc.contributor.authorInitials Huang, BY
dc.contributor.authorInitials Castillo, M
dc.contributor.authorInitials Bassim, MK
dc.contributor.authorInitials Adunka, OF
dc.contributor.authorInitials Buchman, CA
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Buchman, CA (reprint author), Univ N Carolina, Dept Otolaryngol Head and Neck Surg, G190,Phys Off Bldg,CB 7070,170 Manning Dr, Chapel Hill, NC 27599 USA.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 21
dc.description.citedTotWOSCount 19
dc.description.citedWOSCount 16
dc.format.extentCount 9
dc.identifier.articleNo
dc.identifier.coden ONTEA
dc.identifier.pubmedID 20593543
dc.identifier.scopusID 77954361067
dc.identifier.url
dc.publisher.address 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Otol. Neurotol.
dc.relation.ispartOfIssue 5
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Otology and Neurotology
dc.relation.ispartofPubTitleAbbr Otol. Neurotol.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 31
dc.source.ID WOS:000279163000012
dc.type.publication Journal
dc.subject.otherAuthKeyword Auditory dys-synchrony
dc.subject.otherAuthKeyword Auditory neuropathy
dc.subject.otherAuthKeyword Computed tomography
dc.subject.otherAuthKeyword Imaging
dc.subject.otherAuthKeyword Magnetic resonance imaging
dc.subject.otherChemCAS
dc.subject.otherIndex article
dc.subject.otherIndex brain
dc.subject.otherIndex central nervous system
dc.subject.otherIndex cochlea
dc.subject.otherIndex cochlear nerve
dc.subject.otherIndex computer assisted tomography
dc.subject.otherIndex congenital malformation
dc.subject.otherIndex electrophysiology
dc.subject.otherIndex female
dc.subject.otherIndex hearing disorder
dc.subject.otherIndex human
dc.subject.otherIndex infant
dc.subject.otherIndex male
dc.subject.otherIndex nuclear magnetic resonance imaging
dc.subject.otherIndex pathology
dc.subject.otherIndex peripheral neuropathy
dc.subject.otherIndex radiography
dc.subject.otherIndex temporal bone
dc.subject.otherIndex Brain
dc.subject.otherIndex Central Nervous System
dc.subject.otherIndex Cochlea
dc.subject.otherIndex Cochlear Nerve
dc.subject.otherIndex Electrophysiology
dc.subject.otherIndex Female
dc.subject.otherIndex Hearing Disorders
dc.subject.otherIndex Humans
dc.subject.otherIndex Infant
dc.subject.otherIndex Magnetic Resonance Imaging
dc.subject.otherIndex Male
dc.subject.otherIndex Peripheral Nervous System Diseases
dc.subject.otherIndex Temporal Bone
dc.subject.otherIndex Tomography, X-Ray Computed
dc.subject.otherKeywordPlus SENSORINEURAL HEARING-LOSS
dc.subject.otherKeywordPlus COCHLEAR NERVE DEFICIENCY
dc.subject.otherKeywordPlus MAGNETIC-RESONANCE
dc.subject.otherKeywordPlus COMPUTED-TOMOGRAPHY
dc.subject.otherKeywordPlus OTOACOUSTIC EMISSIONS
dc.subject.otherKeywordPlus TEMPORAL BONE
dc.subject.otherKeywordPlus IMPLANTATION
dc.subject.otherKeywordPlus INFANTS
dc.subject.otherKeywordPlus POTENTIALS
dc.subject.otherKeywordPlus MANAGEMENT
dc.subject.otherWOS Clinical Neurology
dc.subject.otherWOS Otorhinolaryngology


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