AUB ScholarWorks

Identification of bacteria isolated from nasal polyps and their ability to produce superantigens and biofilms in Lebanese patients

Show simple item record

dc.contributor.author Chakhtoura M.
dc.contributor.author Hadi U.
dc.contributor.author Rameh C.
dc.contributor.author Nassar J.
dc.contributor.author Abdelnoor A.M.
dc.contributor.editor
dc.date 2011
dc.date.accessioned 2017-10-05T15:50:33Z
dc.date.available 2017-10-05T15:50:33Z
dc.date.issued 2011
dc.identifier
dc.identifier.isbn
dc.identifier.issn 01455613
dc.identifier.uri http://hdl.handle.net/10938/18932
dc.description.abstract Staphylococcus aureus superantigens and bacterial biofilms have been implicated in the development of chronic rhinosinusitis and nasal polyps. We conducted a study of 32 Lebanese patients-21 males and 11 females, aged 15 to 71 years (mean: 39)-to identify bacteria isolated from nasal polyps and to determine if these bacteria produced superantigens and biofilms. Polyps were surgically removed, homogenized, and subjected to bacteriologic studies. The presence or absence of S aureus enterotoxin A, B, C, and D (superantigen) genes was determined in all isolates by polymerase chain reaction. Biofilm production by coagulase-negative staphylococci and Pseudomonas aeruginosa was assessed by tissue culture plate assay. A total of 34 bacterial species-groups were isolated from the nasal polyps. Of these, only 3 (8.8percent) were S aureus, and only 1 possessed an enterotoxin-coding gene (enterotoxin B). Moreover, of the 21 coagulase-negative staphylococci isolates that were found, none possessed the investigated genes, and only 1 had a strong biofilm-formation property. Our results could not confirm that S aureus enterotoxins (superantigens) or biofilm-producing bacteria play a role in the development of nasal polyps in the Lebanese group studied. © 2011, Vendome Group, LLC.
dc.format.extent
dc.language English
dc.relation.ispartof Publication Name: Ear, Nose and Throat Journal; Publication Year: 2011; Volume: 90; no. 4;
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Identification of bacteria isolated from nasal polyps and their ability to produce superantigens and biofilms in Lebanese patients
dc.type Article
dc.contributor.affiliation Chakhtoura, M., The Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, The Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Hadi, U., The Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, The Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Rameh, C., The Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, The Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Nassar, J., The Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, The Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Abdelnoor, A.M., The Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, The Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.authorAddress Abdelnoor, A.M.; Department of Microbiology and Immunology, Faculty of Medicine, American University of Beirut, Bliss St., Beirut 1107 2020, Lebanon; email: aanoor@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Otolaryngology;
dc.contributor.authorDepartment Otolaryngology
dc.contributor.authorDivision
dc.contributor.authorEmail
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials empty
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited
dc.description.citedCount 1
dc.description.citedTotWOSCount
dc.description.citedWOSCount
dc.format.extentCount 1
dc.identifier.articleNo
dc.identifier.coden ENTJD
dc.identifier.pubmedID
dc.identifier.scopusID 79955632347
dc.identifier.url
dc.publisher.address
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr
dc.relation.ispartOfIssue 4
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle Ear, Nose and Throat Journal
dc.relation.ispartofPubTitleAbbr Ear Nose Throat J.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 90
dc.source.ID
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS Staphylococcus enterotoxin A, 37337-57-8
dc.subject.otherChemCAS Staphylococcus enterotoxin B, 39424-53-8
dc.subject.otherChemCAS Staphylococcus enterotoxin C, 39424-54-9
dc.subject.otherChemCAS staphylococcus enterotoxin d, 12788-99-7
dc.subject.otherIndex Staphylococcus enterotoxin
dc.subject.otherIndex Staphylococcus enterotoxin A
dc.subject.otherIndex Staphylococcus enterotoxin B
dc.subject.otherIndex Staphylococcus enterotoxin C
dc.subject.otherIndex staphylococcus enterotoxin d
dc.subject.otherIndex superantigen
dc.subject.otherIndex unclassified drug
dc.subject.otherIndex adolescent
dc.subject.otherIndex adult
dc.subject.otherIndex aged
dc.subject.otherIndex allergic rhinitis
dc.subject.otherIndex alpha hemolytic Streptococcus
dc.subject.otherIndex article
dc.subject.otherIndex bacterium identification
dc.subject.otherIndex bacterium isolation
dc.subject.otherIndex biofilm
dc.subject.otherIndex chronic disease
dc.subject.otherIndex Citrobacter koseri
dc.subject.otherIndex clinical article
dc.subject.otherIndex coagulase negative Staphylococcus
dc.subject.otherIndex Enterobacter aerogenes
dc.subject.otherIndex female
dc.subject.otherIndex human
dc.subject.otherIndex Lebanon
dc.subject.otherIndex male
dc.subject.otherIndex nose polyp
dc.subject.otherIndex Proteus mirabilis
dc.subject.otherIndex Pseudomonas aeruginosa
dc.subject.otherIndex rhinosinusitis
dc.subject.otherIndex Staphylococcus aureus
dc.subject.otherIndex Streptococcus pyogenes
dc.subject.otherIndex tissue culture technique
dc.subject.otherKeywordPlus
dc.subject.otherWOS


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search AUB ScholarWorks


Browse

My Account