Abstract:
Looking for therapeutic options, we assessed the minimum inhibitory concentrations (MICs) of 7 antimicrobial agents against extended-spectrum β-lactamase-producing Klebsiella pneumoniae (n = 58) and Escherichia coli (n = 84) isolates. High rates of susceptibility were shown for both E coli and K pneumoniae against ertapenem (100percent for both), piperacillin-tazobactam (83percent and 91percent, respectively) and amikacin (96percent and 82percent, respectively). In addition, most K pneumoniae isolates were susceptible to quinolones (72percent-75percent) and cefepime (88percent). However, clinical correlation is warranted. Copyright © 2005 by the Association for Professionals in Infection Control and Epidemiology, Inc.