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In vitro activity of antimicrobial agents against extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care center in Lebanon

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dc.contributor.author Samaha-Kfoury J.N.
dc.contributor.author Kanj S.S.
dc.contributor.author Araj G.F.
dc.contributor.editor
dc.date Apr-2005
dc.date.accessioned 2017-10-05T15:59:24Z
dc.date.available 2017-10-05T15:59:24Z
dc.date.issued 2005
dc.identifier 10.1016/j.ajic.2004.10.006
dc.identifier.isbn
dc.identifier.issn 01966553
dc.identifier.uri http://hdl.handle.net/10938/18989
dc.description.abstract Looking for therapeutic options, we assessed the minimum inhibitory concentrations (MICs) of 7 antimicrobial agents against extended-spectrum β-lactamase-producing Klebsiella pneumoniae (n = 58) and Escherichia coli (n = 84) isolates. High rates of susceptibility were shown for both E coli and K pneumoniae against ertapenem (100percent for both), piperacillin-tazobactam (83percent and 91percent, respectively) and amikacin (96percent and 82percent, respectively). In addition, most K pneumoniae isolates were susceptible to quinolones (72percent-75percent) and cefepime (88percent). However, clinical correlation is warranted. Copyright © 2005 by the Association for Professionals in Infection Control and Epidemiology, Inc.
dc.format.extent
dc.format.extent Pages: (134-136)
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: American Journal of Infection Control; Publication Year: 2005; Volume: 33; no. 3; Pages: (134-136);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title In vitro activity of antimicrobial agents against extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care center in Lebanon
dc.type Article
dc.contributor.affiliation Samaha-Kfoury, J.N., Dept. of Pathol. and Lab. Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Kanj, S.S., Division of Infectious Diseases, Department of Internal Medicine, Amer. Univ. of Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Araj, G.F., Dept. of Pathol. and Lab. Medicine, American University, Beirut Medical Center, Beirut, Lebanon, Dept. of Pathol. and Lab. Medicine, American University, Beirut Medical Center, PO Box 113-6044, Hamra 110 32090, Beirut, Lebanon
dc.contributor.authorAddress Araj, G.F.; Dept. of Pathol. and Lab. Medicine, American University, Beirut Medical Center, PO Box 113-6044, Hamra 110 32090, Beirut, Lebanon; email: garaj@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Pathology and Laboratory Medicine;
dc.contributor.authorDepartment Pathology and Laboratory Medicine
dc.contributor.authorDivision
dc.contributor.authorEmail garaj@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Samaha-Kfoury, JN
dc.contributor.authorInitials Kanj, SS
dc.contributor.authorInitials Araj, GF
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Araj, GF (reprint author), Amer Univ Beirut, Dept Pathol and Lab Med, Ctr Med, POB 113-6044,Hamra 110 32090, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Araj G F, 2000, J Med Liban, V48, P221; Bradford PA, 2001, CLIN MICROBIOL REV, V14, P933, DOI 10.1128-CMR.14.4.933-951.2001; Iqbal M, 2002, J Pak Med Assoc, V52, P407; Jones LE, 1997, J ECON DYN CONTROL, V21, P1, DOI 10.1016-0165-1889(95)00924-8; KANAFANI ZA, 2004, 44 ICAAC OCT 29 NOV; Kanj S S, 2001, J Med Liban, V49, P13; Livermore DM, 2001, ANTIMICROB AGENTS CH, V45, P2831, DOI 10.1128-AAC.45.10.2831-2837.2001; National Committee for Clinical Laboratory Standards, 2002, M100S12 NAT COMM CLI; Nishino Takeshi, 2002, Nihon Rinsho, V60, P2216; Paterson DL, 2001, J CLIN MICROBIOL, V39, P2206, DOI 10.1128-JCM.39.6.2206-2212.2001; Samaha-Kfoury JN, 2003, BRIT MED J, V327, P1209, DOI 10.1136-bmj.327.7425.1209; Spanu T, 2002, ANTIMICROB AGENTS CH, V46, P196, DOI 10.1128-AAC.46.1.196-202.2002; Zanetti G, 2003, ANTIMICROB AGENTS CH, V47, P3442, DOI 10.1128-AAC.47.11.3442-3447.2003
dc.description.citedCount 9
dc.description.citedTotWOSCount 6
dc.description.citedWOSCount 6
dc.format.extentCount 3
dc.identifier.articleNo
dc.identifier.coden AJICD
dc.identifier.pubmedID 15798666
dc.identifier.scopusID 15744381058
dc.identifier.url
dc.publisher.address 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
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dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Am. J. Infect. Control
dc.relation.ispartOfIssue 3
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle American Journal of Infection Control
dc.relation.ispartofPubTitleAbbr Am. J. Infect. Control
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 33
dc.source.ID WOS:000228304100002
dc.type.publication Journal
dc.subject.otherAuthKeyword
dc.subject.otherChemCAS amikacin, 37517-28-5, 39831-55-5
dc.subject.otherChemCAS amoxicillin plus clavulanic acid, 74469-00-4, 79198-29-1
dc.subject.otherChemCAS beta lactamase, 9073-60-3
dc.subject.otherChemCAS cefepime, 88040-23-7
dc.subject.otherChemCAS ceftazidime, 72558-82-8
dc.subject.otherChemCAS ciprofloxacin, 85721-33-1
dc.subject.otherChemCAS ertapenem, 153773-82-1, 153832-38-3, 153832-46-3
dc.subject.otherChemCAS levofloxacin, 100986-85-4, 138199-71-0
dc.subject.otherChemCAS Anti-Bacterial Agents
dc.subject.otherChemCAS beta-Lactamases, EC 3.5.2.6
dc.subject.otherIndex amikacin
dc.subject.otherIndex amoxicillin plus clavulanic acid
dc.subject.otherIndex antibiotic agent
dc.subject.otherIndex antiinfective agent
dc.subject.otherIndex bacterial enzyme
dc.subject.otherIndex beta lactamase
dc.subject.otherIndex cefepime
dc.subject.otherIndex ceftazidime
dc.subject.otherIndex ciprofloxacin
dc.subject.otherIndex ertapenem
dc.subject.otherIndex levofloxacin
dc.subject.otherIndex piperacillin plus tazobactam
dc.subject.otherIndex quinolone derivative
dc.subject.otherIndex antibiotic sensitivity
dc.subject.otherIndex antimicrobial activity
dc.subject.otherIndex article
dc.subject.otherIndex bacterium isolate
dc.subject.otherIndex controlled study
dc.subject.otherIndex drug efficacy
dc.subject.otherIndex Escherichia coli
dc.subject.otherIndex health care
dc.subject.otherIndex Klebsiella pneumoniae
dc.subject.otherIndex Lebanon
dc.subject.otherIndex minimum inhibitory concentration
dc.subject.otherIndex nonhuman
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Aged
dc.subject.otherIndex Anti-Bacterial Agents
dc.subject.otherIndex beta-Lactamases
dc.subject.otherIndex Child
dc.subject.otherIndex Child, Preschool
dc.subject.otherIndex Drug Resistance, Multiple, Bacterial
dc.subject.otherIndex Escherichia coli
dc.subject.otherIndex Escherichia coli Infections
dc.subject.otherIndex Female
dc.subject.otherIndex Hospitals, University
dc.subject.otherIndex Humans
dc.subject.otherIndex Infant
dc.subject.otherIndex Klebsiella Infections
dc.subject.otherIndex Klebsiella pneumoniae
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherKeywordPlus ENTEROBACTERIACEAE
dc.subject.otherKeywordPlus RESISTANCE
dc.subject.otherWOS Infectious Diseases


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