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Successful pregnancy involving a man with chronic myeloid leukemia on dasatinib

Show simple item record Oweini H. Otrock Z.K. Mahfouz R.A.R. Bazarbachi A.
dc.contributor.editor Jan-2011 2017-10-05T15:59:29Z 2017-10-05T15:59:29Z 2011
dc.identifier 10.1007/s00404-010-1501-6
dc.identifier.issn 09320067
dc.description.abstract Dasatinib is a highly potent Bcr-Abl inhibitor that is approved for the treatment of imatinib-resistant or -intolerant chronic myeloid leukemia (CML). The potential effects of dasatinib on sperm counts, sperm function, and fertility have not been studied yet. There is only one report in the medical literature of successful pregnancies while patients were taking dasatinib, thus making our case the second report. Here, we present the case of a 38-year-old man who conceived a healthy baby while on dasatinib therapy. © 2010 Springer-Verlag.
dc.format.extent Pages: (133-134)
dc.language English
dc.publisher HEIDELBERG
dc.relation.ispartof Publication Name: Archives of Gynecology and Obstetrics; Publication Year: 2011; Volume: 283; no. 1; Pages: (133-134);
dc.source Scopus
dc.title Successful pregnancy involving a man with chronic myeloid leukemia on dasatinib
dc.type Article
dc.contributor.affiliation Oweini, H., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Otrock, Z.K., Department of Pathology and Laboratory Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Mahfouz, R.A.R., Department of Pathology and Laboratory Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.affiliation Bazarbachi, A., Department of Internal Medicine, American University, Beirut Medical Center, Beirut, Lebanon
dc.contributor.authorAddress Bazarbachi, A.; Bone Marrow Transplantation Program, Department of Medicine, American University of Beirut Medical Center, P.O. Box 113-6044, Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Pathology and Laboratory Medicine;
dc.contributor.authorDepartment Pathology and Laboratory Medicine
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Oweini, H
dc.contributor.authorInitials Otrock, ZK
dc.contributor.authorInitials Mahfouz, RAR
dc.contributor.authorInitials Bazarbachi, A
dc.contributor.authorReprintAddress Bazarbachi, A (reprint author), Amer Univ Beirut, Med Ctr, Bone Marrow Transplantat Program, Dept Med, POB 113-6044, Beirut, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited [Anonymous], 2012, HIGHLIGHTS PRESCRIBI, V26; Ault P, 2006, J CLIN ONCOL, V24, P1204, DOI 10.1200-JCO.2005.04.6557; Cortes J, 2008, BLOOD, V112; Deininger Michael W, 2008, Hematology Am Soc Hematol Educ Program, P419, DOI 10.1182-asheducation-2008.1.419; Lichtman MA, 2001, WILLIAMS HEMATOLOGY, P1047; Sawyers CL, 1999, NEW ENGL J MED, V340, P1330, DOI 10.1056-NEJM199904293401706
dc.description.citedCount 9
dc.description.citedTotWOSCount 12
dc.description.citedWOSCount 8
dc.format.extentCount 2
dc.identifier.coden AGOBE
dc.identifier.pubmedID 20473616
dc.identifier.scopusID 78751591628
dc.publisher.address TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY
dc.relation.ispartOfISOAbbr Arch. Gynecol. Obstet.
dc.relation.ispartOfIssue 1
dc.relation.ispartofPubTitle Archives of Gynecology and Obstetrics
dc.relation.ispartofPubTitleAbbr Arch. Gynecol. Obstet.
dc.relation.ispartOfVolume 283
dc.source.ID WOS:000285784000023
dc.type.publication Journal
dc.subject.otherAuthKeyword Chronic myeloid leukemia
dc.subject.otherAuthKeyword Dasatinib
dc.subject.otherAuthKeyword Pregnancy
dc.subject.otherChemCAS dasatinib, 302962-49-8
dc.subject.otherChemCAS hydroxyurea, 127-07-1
dc.subject.otherChemCAS imatinib, 152459-95-5, 220127-57-1
dc.subject.otherChemCAS nilotinib, 641571-10-0
dc.subject.otherChemCAS Antineoplastic Agents
dc.subject.otherChemCAS Protein Kinase Inhibitors
dc.subject.otherChemCAS Pyrimidines
dc.subject.otherChemCAS Thiazoles
dc.subject.otherChemCAS dasatinib, 302962-49-8
dc.subject.otherIndex dasatinib
dc.subject.otherIndex hydroxyurea
dc.subject.otherIndex imatinib
dc.subject.otherIndex interferon
dc.subject.otherIndex nilotinib
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex ascites
dc.subject.otherIndex cancer resistance
dc.subject.otherIndex case report
dc.subject.otherIndex chronic myeloid leukemia
dc.subject.otherIndex conception
dc.subject.otherIndex cytogenetics
dc.subject.otherIndex drug withdrawal
dc.subject.otherIndex hepatosplenomegaly
dc.subject.otherIndex human
dc.subject.otherIndex human cell
dc.subject.otherIndex leukocyte count
dc.subject.otherIndex maintenance therapy
dc.subject.otherIndex male
dc.subject.otherIndex pericardial effusion
dc.subject.otherIndex Philadelphia chromosome positive cell
dc.subject.otherIndex pleura effusion
dc.subject.otherIndex pregnancy outcome
dc.subject.otherIndex treatment duration
dc.subject.otherIndex treatment response
dc.subject.otherIndex Adult
dc.subject.otherIndex Antineoplastic Agents
dc.subject.otherIndex Female
dc.subject.otherIndex Fertilization
dc.subject.otherIndex Humans
dc.subject.otherIndex Infant
dc.subject.otherIndex Leukemia, Myelogenous, Chronic, BCR-ABL Positive
dc.subject.otherIndex Male
dc.subject.otherIndex Pregnancy
dc.subject.otherIndex Protein Kinase Inhibitors
dc.subject.otherIndex Pyrimidines
dc.subject.otherIndex Thiazoles
dc.subject.otherWOS Obstetrics and Gynecology

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