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Distribution of killer cell immunoglobulin-like receptors genotypes in the Lebanese population

Show simple item record Mahfouz R. Rayes R. Mahfoud Z. Bazarbachi A. Zaatari G.
dc.contributor.editor Jul-2006 2017-10-05T15:59:42Z 2017-10-05T15:59:42Z 2006
dc.identifier 10.1111/j.1399-0039.2006.00605.x
dc.identifier.issn 00012815
dc.description.abstract This study represents the first report on the distribution of 16 Killer cell Immunoglobulin-like Receptors (KIR) genes in 120 unrelated healthy Lebanese individuals. We observed that 2DL2 frequency (61percent) comes second highest after South Asians (64percent) and 2DL5 frequency (58.3percent) is the second highest reported so far after the South Asians (74percent). Interestingly, a large number of AA1 genotype individuals with no loci for activating KIR and three completely new BB profiles not previously reported were found in our population with a group A : group B haplotypes ratio of 1.3:1. The frequency of the KIR loci suggests that the Lebanese population shares common general features with the Caucasoid populations studied before, but still has its own unique decreased or increased frequencies of several loci. © 2006 The Authors.
dc.format.extent Pages: (66-71)
dc.language English
dc.publisher OXFORD
dc.relation.ispartof Publication Name: Tissue Antigens; Publication Year: 2006; Volume: 68; no. 1; Pages: (66-71);
dc.source Scopus
dc.title Distribution of killer cell immunoglobulin-like receptors genotypes in the Lebanese population
dc.type Article
dc.contributor.affiliation Mahfouz, R., Department of Pathology and Laboratory Medicine, AUBMC, Lebanon, Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center (AUBMC), PO Box 11-0236, Riad El Solh 1107,2020 Beirut, Lebanon
dc.contributor.affiliation Rayes, R., Department of Pathology and Laboratory Medicine, AUBMC, Lebanon
dc.contributor.affiliation Mahfoud, Z., Department of Epidemiology and Population Health, AUB
dc.contributor.affiliation Bazarbachi, A., Department of Internal Medicine, AUBMC
dc.contributor.affiliation Zaatari, G., Department of Pathology and Laboratory Medicine, AUBMC, Lebanon
dc.contributor.authorAddress Mahfouz, R.; Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center (AUBMC), PO Box 11-0236, Riad El Solh 1107,2020 Beirut, Lebanon; email:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Pathology and Laboratory Medicine;
dc.contributor.authorDepartment Pathology and Laboratory Medicine
dc.contributor.faculty Faculty of Medicine
dc.contributor.authorInitials Mahfouz, R
dc.contributor.authorInitials Rayes, R
dc.contributor.authorInitials Mahfoud, Z
dc.contributor.authorInitials Bazarbachi, A
dc.contributor.authorInitials Zaatari, G
dc.contributor.authorReprintAddress Mahfouz, R (reprint author), Amer Univ Beirut, Med Ctr, Dept Pathol and Lab Med, POB 11-0236,Riad El Solh 1107, Beirut 2020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 19
dc.description.citedTotWOSCount 23
dc.description.citedWOSCount 20
dc.format.extentCount 6
dc.identifier.coden TSANA
dc.identifier.pubmedID 16774542
dc.identifier.scopusID 33745125709
dc.publisher.address 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND
dc.relation.ispartOfISOAbbr Tissue Antigens
dc.relation.ispartOfIssue 1
dc.relation.ispartofPubTitle Tissue Antigens
dc.relation.ispartofPubTitleAbbr Tissue Antigens
dc.relation.ispartOfVolume 68
dc.source.ID WOS:000238186900009
dc.type.publication Journal
dc.subject.otherAuthKeyword Genotype
dc.subject.otherAuthKeyword KIR
dc.subject.otherAuthKeyword Lebanese
dc.subject.otherAuthKeyword Prevalence
dc.subject.otherChemCAS Receptors, Immunologic
dc.subject.otherChemCAS killer cell immunoglobulin-like receptor
dc.subject.otherIndex killer cell immunoglobulin like receptor
dc.subject.otherIndex article
dc.subject.otherIndex Asian
dc.subject.otherIndex Caucasian
dc.subject.otherIndex controlled study
dc.subject.otherIndex gene frequency
dc.subject.otherIndex gene locus
dc.subject.otherIndex genotype
dc.subject.otherIndex haplotype
dc.subject.otherIndex human
dc.subject.otherIndex Lebanon
dc.subject.otherIndex priority journal
dc.subject.otherIndex South Asia
dc.subject.otherIndex Demography
dc.subject.otherIndex Gene Frequency
dc.subject.otherIndex Genotype
dc.subject.otherIndex Haplotypes
dc.subject.otherIndex Humans
dc.subject.otherIndex Lebanon
dc.subject.otherIndex Prevalence
dc.subject.otherIndex Receptors, Immunologic
dc.subject.otherKeywordPlus GENE CONTENT
dc.subject.otherKeywordPlus ALLELIC POLYMORPHISM
dc.subject.otherKeywordPlus PSORIASIS-VULGARIS
dc.subject.otherKeywordPlus HAPLOTYPE ANALYSIS
dc.subject.otherKeywordPlus GENOMIC DIVERSITY
dc.subject.otherKeywordPlus KIR HAPLOTYPES
dc.subject.otherKeywordPlus HLA
dc.subject.otherKeywordPlus DISEASE
dc.subject.otherKeywordPlus TRANSPLANTATION
dc.subject.otherKeywordPlus SUSCEPTIBILITY
dc.subject.otherWOS Cell Biology
dc.subject.otherWOS Immunology
dc.subject.otherWOS Pathology

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