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Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia

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dc.contributor.author Khoury B.
dc.contributor.author Musallam K.M.
dc.contributor.author Abi-Habib R.
dc.contributor.author Bazzi L.
dc.contributor.author Koussa S.
dc.contributor.author Taher A.T.
dc.contributor.author Al Ward Z.
dc.contributor.author Succar J.
dc.contributor.author Halawi R.
dc.contributor.author Hankir A.
dc.contributor.editor
dc.date Dec-2012
dc.date.accessioned 2017-10-05T16:04:44Z
dc.date.available 2017-10-05T16:04:44Z
dc.date.issued 2012
dc.identifier 10.2190/PM.44.4.a
dc.identifier.isbn
dc.identifier.issn 00912174
dc.identifier.uri http://hdl.handle.net/10938/19658
dc.description.abstract Objective: To evaluate and compare the prevalence and risk factors for anxiety and depression in adults with β-thalassemia major (TM) and intermedia (TI). Method: A cross-sectional study of TI and TM patients at a Chronic Care Center in Lebanon. A total of 80 patients agreed to participate (32 TI (median age 24 years) and 48 TM (median age 23 years)). The Beck Depression Inventory (BDI) and State-Trait Anxiety Inventory (STAI) questionnaires were used to assess the depression and anxiety levels of patients, respectively. Data on patient demographics, clinical complications, and socioeconomic status were also collected. Results: Patients with TM had a significantly longer median duration with a known thalassemia diagnosis than patients with TI (p 0.001). A considerable proportion of patients had depression (35.0percent), State (S)-anxiety (22.5percent) or Trait (T)-anxiety (36.2percent). Patients with TI had a higher median S-anxiety score compared with TM (p = 0.035), although the median T-anxiety and depression scores were similar. On linear regression analysis, the significant association between the thalassemia diagnosis (TM versus TI) and S-anxiety score (beta:5.740;95percent CI:0.201 to 11.278;p = 0.042) was no longer observed upon adjustment for the co-variate duration with a known thalassemia diagnosis (beta:3.162;95percent CI:-2.949 to 9.274;p = 0.306). Conclusions: A considerable proportion of adult patients with TM and TI show evidence of depression and anxiety. Patients with TI are more liable to state anxiety than TM patients of a similar age, which is attributed to a shorter duration of living with a thalassemia diagnosis.
dc.format.extent
dc.format.extent Pages: (291-303)
dc.language English
dc.publisher AMITYVILLE
dc.relation.ispartof Publication Name: International Journal of Psychiatry in Medicine; Publication Year: 2012; Volume: 44; no. 4; Pages: (291-303);
dc.relation.ispartofseries
dc.relation.uri
dc.source Scopus
dc.subject.other
dc.title Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia
dc.type Article
dc.contributor.affiliation Khoury, B., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Musallam, K.M., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Abi-Habib, R., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Bazzi, L., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Koussa, S., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Taher, A.T., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Al Ward, Z., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Succar, J., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon
dc.contributor.affiliation Halawi, R., Chronic Care Center, Hazmieh, Lebanon
dc.contributor.affiliation Hankir, A., American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon, Chronic Care Center, Hazmieh, Lebanon
dc.contributor.authorAddress Taher, A.T.; American University of Beirut, Medical Center, Research Department of Internal Medicine, Riad El-Solh 1107, 2020 Beirut, Lebanon; email: ataher@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Psychiatry;
dc.contributor.authorDepartment Psychiatry
dc.contributor.authorDivision
dc.contributor.authorEmail ataher@aub.edu.lb
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Khoury, B
dc.contributor.authorInitials Al Ward, Z
dc.contributor.authorInitials Musallam, KM
dc.contributor.authorInitials Succar, J
dc.contributor.authorInitials Abi-Habib, R
dc.contributor.authorInitials Halawi, R
dc.contributor.authorInitials Bazzi, L
dc.contributor.authorInitials Hankir, A
dc.contributor.authorInitials Koussa, S
dc.contributor.authorInitials Taher, AT
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Taher, AT (reprint author), Amer Univ Beirut, Dept Internal Med, Med Ctr, POB 11-0236 Riad El Solh 1107 2020, Beirut, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut Medical Center
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dc.description.citedCount 1
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.format.extentCount 13
dc.identifier.articleNo
dc.identifier.coden IJMED
dc.identifier.pubmedID 23885513
dc.identifier.scopusID 84881623681
dc.identifier.url
dc.publisher.address 26 AUSTIN AVE, PO BOX 337, AMITYVILLE, NY 11701 USA
dc.relation.ispartofConference
dc.relation.ispartofConferenceCode
dc.relation.ispartofConferenceDate
dc.relation.ispartofConferenceHosting
dc.relation.ispartofConferenceLoc
dc.relation.ispartofConferenceSponsor
dc.relation.ispartofConferenceTitle
dc.relation.ispartofFundingAgency
dc.relation.ispartOfISOAbbr Int. J. Psychiatr. Med.
dc.relation.ispartOfIssue 4
dc.relation.ispartOfPart
dc.relation.ispartofPubTitle International Journal of Psychiatry in Medicine
dc.relation.ispartofPubTitleAbbr Int. J. Psychiatry Med.
dc.relation.ispartOfSpecialIssue
dc.relation.ispartOfSuppl
dc.relation.ispartOfVolume 44
dc.source.ID WOS:000316941000001
dc.type.publication Journal
dc.subject.otherAuthKeyword Anxiety
dc.subject.otherAuthKeyword Depression
dc.subject.otherAuthKeyword Thalassemia
dc.subject.otherChemCAS
dc.subject.otherIndex adult
dc.subject.otherIndex anxiety
dc.subject.otherIndex article
dc.subject.otherIndex beta thalassemia
dc.subject.otherIndex controlled study
dc.subject.otherIndex depression
dc.subject.otherIndex female
dc.subject.otherIndex human
dc.subject.otherIndex major clinical study
dc.subject.otherIndex male
dc.subject.otherIndex mental health
dc.subject.otherIndex prevalence
dc.subject.otherIndex risk factor
dc.subject.otherIndex scoring system
dc.subject.otherIndex social status
dc.subject.otherIndex thalassemia major
dc.subject.otherIndex adolescent
dc.subject.otherIndex anxiety
dc.subject.otherIndex beta thalassemia
dc.subject.otherIndex classification
dc.subject.otherIndex comparative study
dc.subject.otherIndex cross-sectional study
dc.subject.otherIndex depression
dc.subject.otherIndex middle aged
dc.subject.otherIndex psychological aspect
dc.subject.otherIndex psychological rating scale
dc.subject.otherIndex severity of illness index
dc.subject.otherIndex time
dc.subject.otherIndex Adolescent
dc.subject.otherIndex Adult
dc.subject.otherIndex Anxiety
dc.subject.otherIndex beta-Thalassemia
dc.subject.otherIndex Cross-Sectional Studies
dc.subject.otherIndex Depression
dc.subject.otherIndex Female
dc.subject.otherIndex Humans
dc.subject.otherIndex Male
dc.subject.otherIndex Middle Aged
dc.subject.otherIndex Prevalence
dc.subject.otherIndex Psychiatric Status Rating Scales
dc.subject.otherIndex Severity of Illness Index
dc.subject.otherIndex Time Factors
dc.subject.otherIndex Young Adult
dc.subject.otherKeywordPlus QUALITY-OF-LIFE
dc.subject.otherKeywordPlus SPLENECTOMIZED ADULTS
dc.subject.otherKeywordPlus YOUNG-ADULTS
dc.subject.otherKeywordPlus BRAIN
dc.subject.otherKeywordPlus DEFERASIROX
dc.subject.otherKeywordPlus ADOLESCENTS
dc.subject.otherKeywordPlus HEMOGLOBIN
dc.subject.otherKeywordPlus TRANSITION
dc.subject.otherKeywordPlus DISORDERS
dc.subject.otherKeywordPlus SYMPTOMS
dc.subject.otherWOS Psychiatry


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