Scholarworks Repository

Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched analysis

Show simple item record Al-Shaar L. Schwann T.A. Kabour A. Habib R.H.
dc.contributor.editor 2014 2017-10-05T16:08:59Z 2017-10-05T16:08:59Z 2014
dc.identifier 10.1016/j.jtcvs.2014.05.020
dc.identifier.issn 00225223
dc.description.abstract Objectives: The association of new-onset postoperative atrial fibrillation (POAF) and late death after coronary artery bypass grafting (CABG) has been confounded by the frequent concomitant serious complications that co-occur with POAF. We aimed to define the magnitude and time dependence of the effect of isolated POAF on late survival after uncomplicated CABG to comprehensively account for comorbidity and perioperative confounding factors. Methods: Nonsalvage CABG patients with no history of AF, no concomitant aortic or valvular surgery, and no perioperative complications other than POAF were studied (n = 6305). Patients were divided into AF (n = 1211, 68 years old, 72percent male) and no-AF (n = 5094, 63 years old, 70percent male) groups. Propensity matching was done using 55 patient variables, including coronary grafts, completeness of revascularization, and transfusion data. The AF effect was quantified using time-segmented hazard ratios by Cox regression analysis. Results: Single (1-to-1), double (1-to-2), and triple (1-to-3) propensity matching of the AF and no-AF was achieved for 1196, 993, and 719 cases, respectively. The AF group showed significantly worse, yet time-varying, 0- to 18-year survival: 0 to 1 year, HR, 1.18 (95percent confidence interval, 0.77-1.81); 1 to 6 years, HR, 1.37 (95percent confidence interval, 1.12 to 1.67); and 6 to 17 years, HR, 1.25 (95percent confidence interval, 1.05 to 1.49). Conclusions: Isolated POAF was associated with a time-varying increase in mortality after CABG. Given these findings and the high incidence of POAF, efforts to reduce POAF should be pursued to potentially improve resource usage, morbidity, and mortality. © 2014 The American Association for Thoracic Surgery.
dc.language English
dc.publisher NEW YORK
dc.relation.ispartof Publication Name: Journal of Thoracic and Cardiovascular Surgery; Publication Year: 2014;
dc.source Scopus
dc.title Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched analysis
dc.type Article in Press
dc.contributor.affiliation Al-Shaar, L., Vascular Medicine Program, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Schwann, T.A., Department of Surgery, University of Toledo College of Medicine, Toledo, Ohio
dc.contributor.affiliation Kabour, A., Mercy Saint Vincent Medical Center, Toledo, Ohio
dc.contributor.affiliation Habib, R.H., Vascular Medicine Program, American University of Beirut, Beirut, Lebanon, Outcomes Research Unit and Department of Internal Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.authorAddress Habib, R.H.; Vascular Medicine Program, American University of Beirut, Beirut, Lebanonemail:
dc.contributor.authorCorporate University: American University of Beirut Medical Center; Faculty: Faculty of Medicine; Department: Vascular Medicine Program;
dc.contributor.authorDepartment Vascular Medicine Program
dc.contributor.authorFaculty Faculty of Medicine
dc.contributor.authorInitials Al-Shaar, L
dc.contributor.authorInitials Schwann, TA
dc.contributor.authorInitials Kabour, A
dc.contributor.authorInitials Habib, RH
dc.contributor.authorReprintAddress Habib, RH (reprint author), Amer Univ, Beirut Med Ctr, Outcomes Res Unit, POB 11-0236, Beirut 11072020, Lebanon.
dc.contributor.authorUniversity American University of Beirut Medical Center
dc.description.cited Ahlsson A, 2009, SCAND CARDIOVASC J, V43, P330, DOI 10.1080-14017430802702291; Almassi GH, 1997, ANN SURG, V226, P501, DOI 10.1097-00000658-199710000-00011; Almassi GH, 2012, J THORAC CARDIOV SUR, V143, P93, DOI 10.1016-j.jtcvs.2011.10.003; Almassi GH, 1997, ANN SURG, V226, P11; Amar D, 2004, J AM COLL CARDIOL, V44, P1248, DOI 10.1016-j.jacc.2004.05.078; Aranki SF, 1996, CIRCULATION, V94, P390; Attaran S, 2011, INTERACT CARDIOV TH, V12, P772, DOI 10.1510-icvts.2010.243782; Austin PC, 2009, COMMUN STAT-SIMUL C, V38, P1228, DOI 10.1080-03610910902859574; Benjamin EJ, 1998, CIRCULATION, V98, P946; Bramer S, 2011, ANN THORAC SURG, V92, P2091, DOI 10.1016-j.athoracsur.2011.06.079; Elahi M, 2003, CIRCULATION, V108, P207, DOI 10.1161-01.cir.0000089188.45285.fd; El-Chami MF, 2010, J AM COLL CARDIOL, V55, P1370, DOI 10.1016-j.jacc.2009.10.058; Engoren M, 2009, ANN THORAC SURG, V88, P95, DOI 10.1016-j.athoracsur.2009.04.047; Engoren MC, 2002, ANN THORAC SURG, V74, P1180, DOI 10.1016-S0003-4975(02)03766-9; Filardo G, 2009, CIRC-CARDIOVASC QUAL, V2, P164, DOI 10.1161-CIRCOUTCOMES.108.816843; Habib RH, 2012, ANN THORAC SURG, V94, P1478, DOI 10.1016-j.athoracsur.2012.05.030; Kaireviciute D, 2009, EUR HEART J, V30, P410, DOI 10.1093-eurheartj-ehn609; Kaw R, 2011, J THORAC CARDIOV SUR, V141, P1305, DOI 10.1016-j.jtcvs.2010.10.040; Khan MN, 2008, NEW ENGL J MED, V359, P1778, DOI 10.1056-NEJMoa0708234; Koch CG, 2006, ANN THORAC SURG, V81, P1650, DOI 10.1016-j.athoracsur.2005.12.037; Lotfi A, 2011, CLIN CARDIOL, V34, P787, DOI 10.1002-clc.21001; Lytle BW, 2004, ANN THORAC SURG, V78, P12; Lytle BW, 2004, ANN THORAC SURG, V78, P2005, DOI 10.1016-j.athoracsur.2004.05.070; Maisel WH, 2001, ANN INTERN MED, V135, P1061; Mariscalco G, 2008, CIRCULATION, V118, P1612, DOI 10.1161-CIRCULATIONAHA.108.777789; Mariscalco G, 2009, ANN THORAC SURG, V88, P1871, DOI 10.1016-j.athoracsur.2009.07.074; Mathew JP, 2004, JAMA-J AM MED ASSOC, V291, P1720, DOI 10.1001-jama.291.14.1720; PETERSEN P, 1989, J CEREBR BLOOD F MET, V9, P422; Roshanali F, 2007, CIRCULATION, V116, P2012, DOI 10.1161-CIRCULATIONAHA.107.727081; Schwann TA, 2012, ANN THORAC SURG, V94, P1485, DOI 10.1016-j.athoracsur.2012.05.029; Tsang TSM, 2002, J AM COLL CARDIOL, V40, P1636, DOI 10.1016-S0735-1097(02)02373-2; Villareal RP, 2004, J AM COLL CARDIOL, V43, P742, DOI 10.1016-j.jacc.2003.11.023; Wang TJ, 2003, CIRCULATION, V107, P2920, DOI 10.1161-01.CIR.0000072767.89944.6E; WOLF PA, 1991, STROKE, V22, P983; Zacharias A, 2005, CIRCULATION, V112, P3247, DOI 10.1161-CIRCULATIONAHA.105.553743-DC1; Zacharias A, 2009, ANN THORAC SURG, V87, P19, DOI 10.1016-j.athoracsur.2008.09.050; Zacharias A, 2010, J THORAC CARDIOV SUR, V139, P1511, DOI 10.1016-j.jtcvs.2009.07.068; Zacharias A, 2004, CIRCULATION, V109, P1489, DOI 10.1161-01.CIR.0000121743.10146.78
dc.description.citedTotWOSCount 1
dc.description.citedWOSCount 1
dc.format.extentCount 1
dc.identifier.coden JTCSA
dc.identifier.scopusID 84901885378
dc.publisher.address 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
dc.relation.ispartOfISOAbbr J. Thorac. Cardiovasc. Surg.
dc.relation.ispartofPubTitle Journal of Thoracic and Cardiovascular Surgery
dc.relation.ispartofPubTitleAbbr J. Thorac. Cardiovasc. Surg.
dc.source.ID WOS:000345132600033
dc.type.publication Journal
dc.subject.otherKeywordPlus LONG-TERM SURVIVAL
dc.subject.otherKeywordPlus INTERNAL THORACIC ARTERY
dc.subject.otherKeywordPlus CARDIAC-SURGERY
dc.subject.otherKeywordPlus RADIAL ARTERY
dc.subject.otherKeywordPlus HEART-FAILURE
dc.subject.otherKeywordPlus RISK
dc.subject.otherKeywordPlus TRANSFUSION
dc.subject.otherKeywordPlus IMPACT
dc.subject.otherKeywordPlus GRAFT
dc.subject.otherKeywordPlus PREDICTORS
dc.subject.otherWOS Cardiac and Cardiovascular Systems
dc.subject.otherWOS Respiratory System
dc.subject.otherWOS Surgery

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search Scholarworks


My Account