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Variation of postprandial PYY3-36 response following ingestion of differing macronutrient meals in obese females

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dc.contributor.author Helou N.
dc.contributor.author Obeid O.
dc.contributor.author Azar S.T.
dc.contributor.author Hwalla N.
dc.contributor.editor
dc.date Jul-08
dc.date.accessioned 2017-10-18T13:24:18Z
dc.date.available 2017-10-18T13:24:18Z
dc.date.issued 2008
dc.identifier 10.1159/000138122
dc.identifier.issn 2506807
dc.identifier.uri http://hdl.handle.net/10938/20252
dc.description.abstract Aim: This study investigated the effect of macronutrient composition of meals on postprandial peptide YY3-36 (PYY3-36) response in obese hyperinsulinemic females. Methods: Eight obese females consumed three iso-energetic meals of different macronutrient composition, high carbohydrate (HC; 60percent CHO, 20percent protein, 20percent fat), high fat (HF; 30percent CHO, 20percent protein, 50percent fat) and high protein (HP; 30percent CHO, 50percent protein, 20percent fat), on three separate occasions, 1 month apart. PYY3-36, insulin and glucosewere measured before and 15, 30, 60, 120 and 180 min following each meal. Results: PYY 3-36 levelsincreased significantly following the three meals, with the HC meal resulting in a sustained postprandial increase in PYY3-36 level throughout the experimental period. Comparing the three meals, the HF meal induced a significantly higher increase in postprandial PYY3-36 levels, at 15 and 30 min as compared to the HP meal (p andlt; 0.05), whereas the postprandial increase following the HP meal became significantly higher than that following the HF meal at 120 min. Postprandial increase in PYY 3-36 was highest in the first hour following the HF meal, while that following the HP meal was delayed by 1 h. Conclusion: Increasing both protein and fat content of a meal may induce an immediate and prolonged increase in PYY3-36, resulting in increased satiety and its maintenance for a longer period of time. Copyright © 2008 S. Karger AG.
dc.format.extent Pages: (188-195)
dc.language English
dc.publisher BASEL
dc.relation.ispartof Publication Name: Annals of Nutrition and Metabolism; Publication Year: 2008; Volume: 52; no. 3; Pages: (188-195);
dc.source Scopus
dc.title Variation of postprandial PYY3-36 response following ingestion of differing macronutrient meals in obese females
dc.type Article
dc.contributor.affiliation Helou, N., Department of Nutrition and Food Science, Faculty of Agriculture and Food Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Obeid, O., Department of Nutrition and Food Science, Faculty of Agriculture and Food Sciences, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Azar, S.T., Department of Internal Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon
dc.contributor.affiliation Hwalla, N., Department of Nutrition and Food Science, Faculty of Agriculture and Food Sciences, American University of Beirut, Beirut, Lebanon, Faculty of Agricultural and Food Sciences, American University of Beirut, PO Box 11-0236, Riad El Solh Beirut 1107-2020, Lebanon
dc.contributor.authorAddress Hwalla, N.; Faculty of Agricultural and Food Sciences, American University of Beirut, PO Box 11-0236, Riad El Solh Beirut 1107-2020, Lebanon; email: nahla@aub.edu.lb
dc.contributor.authorCorporate University: American University of Beirut; Faculty: Faculty of Agricultural and Food Sciences; Department: Nutrition and Food Sciences;
dc.contributor.authorDepartment Nutrition and Food Sciences
dc.contributor.authorDivision
dc.contributor.authorEmail nahla@aub.edu.lb
dc.contributor.authorFaculty Faculty of Agricultural and Food Sciences
dc.contributor.authorInitials Helou, N
dc.contributor.authorInitials Obeid, O
dc.contributor.authorInitials Azar, ST
dc.contributor.authorInitials Hwalla, N
dc.contributor.authorOrcidID
dc.contributor.authorReprintAddress Hwalla, N (reprint author), Amer Univ Beirut, Fac Agr and Food Sci, Dept Nutr and Food Sci, POB 11-0236, Beirut 11072020, Lebanon.
dc.contributor.authorResearcherID
dc.contributor.authorUniversity American University of Beirut
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dc.description.citedCount 35
dc.description.citedTotWOSCount 33
dc.description.citedWOSCount 32
dc.format.extentCount 8
dc.identifier.coden ANUMD
dc.identifier.pubmedID 18544972
dc.identifier.scopusID 47249110795
dc.publisher.address ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND
dc.relation.ispartOfISOAbbr Ann. Nutr. Metab.
dc.relation.ispartOfIssue 3
dc.relation.ispartofPubTitle Annals of Nutrition and Metabolism
dc.relation.ispartofPubTitleAbbr Ann. Nutr. Metab.
dc.relation.ispartOfVolume 52
dc.source.ID WOS:000257477400003
dc.type.publication Journal
dc.subject.otherAuthKeyword Glucose
dc.subject.otherAuthKeyword insulin
dc.subject.otherAuthKeyword insulin resistance
dc.subject.otherAuthKeyword meal composition
dc.subject.otherAuthKeyword obesity
dc.subject.otherAuthKeyword postprandial peptide yy3-36
dc.subject.otherChemCAS Glucose, 50-99-7, 84778-64-3
dc.subject.otherChemCAS insulin, 9004-10-8
dc.subject.otherChemCAS blood glucose
dc.subject.otherChemCAS dietary carbohydrates
dc.subject.otherChemCAS dietary fats
dc.subject.otherChemCAS dietary proteins
dc.subject.otherChemCAS peptide yy (3-36), 123583-37-9
dc.subject.otherChemCAS peptide yy, 106388-42-5
dc.subject.otherIndex Glucose
dc.subject.otherIndex insulin
dc.subject.otherIndex peptide yy [3-36]
dc.subject.otherIndex adult
dc.subject.otherIndex article
dc.subject.otherIndex carbohydrate diet
dc.subject.otherIndex clinical article
dc.subject.otherIndex female
dc.subject.otherIndex glucose blood level
dc.subject.otherIndex human
dc.subject.otherIndex hyperinsulinemia
dc.subject.otherIndex insulin blood level
dc.subject.otherIndex lipid diet
dc.subject.otherIndex macronutrient
dc.subject.otherIndex obesity
dc.subject.otherIndex postprandial state
dc.subject.otherIndex priority journal
dc.subject.otherIndex protein diet
dc.subject.otherIndex satiety
dc.subject.otherIndex adult
dc.subject.otherIndex area under curve
dc.subject.otherIndex blood glucose
dc.subject.otherIndex cross-over studies
dc.subject.otherIndex dietary carbohydrates
dc.subject.otherIndex dietary fats
dc.subject.otherIndex dietary proteins
dc.subject.otherIndex female
dc.subject.otherIndex humans
dc.subject.otherIndex obesity
dc.subject.otherIndex peptide yy
dc.subject.otherIndex postprandial period
dc.subject.otherIndex satiety response
dc.subject.otherKeywordPlus Glucagon-like peptide-1
dc.subject.otherKeywordPlus gastric bypass-surgery
dc.subject.otherKeywordPlus gender-specific manner
dc.subject.otherKeywordPlus body-weight regulation
dc.subject.otherKeywordPlus high-carbohydrate
dc.subject.otherKeywordPlus food-intake
dc.subject.otherKeywordPlus gut hormone
dc.subject.otherKeywordPlus high-fat
dc.subject.otherKeywordPlus yy
dc.subject.otherKeywordPlus ghrelin
dc.subject.otherWOS Endocrinology and Metabolism
dc.subject.otherWOS Nutrition and Dietetics
dc.identifier.doi http://dx.doi.org/10.1159/000138122


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