dc.contributor.author |
Naja F. |
dc.contributor.author |
Nasreddine L. |
dc.contributor.author |
Hwalla N. |
dc.contributor.author |
Moghames P. |
dc.contributor.author |
Shoaib H. |
dc.contributor.author |
Fatfat M. |
dc.contributor.author |
Sibai A. |
dc.contributor.author |
Gali-Muhtasib H. |
dc.contributor.editor |
|
dc.date |
2012 |
dc.date.accessioned |
2017-10-18T13:24:33Z |
dc.date.available |
2017-10-18T13:24:33Z |
dc.date.issued |
2012 |
dc.identifier |
10.1111/j.1523-5378.2012.00970.x |
dc.identifier.issn |
10834389 |
dc.identifier.uri |
http://hdl.handle.net/10938/20299 |
dc.description.abstract |
Background: Several epidemiological studies proposed an association between Helicobacter pylori ( H. pylori) infection with insulin resistance (IR) and metabolic syndrome (MetS). However, up to date there is no conclusive evidence regarding this association. Objectives: To investigate the prevalence and correlates of H. pylori infection among Lebanese adults and to evaluate its association with IR and MetS. Materials and Methods: Stored blood samples of adults participating in the national Nutrition and Non-Communicable Diseases Risk factors survey conducted in Lebanon were used for this study (n = 308). H. pylori-specific immunoglobulin G antibody titers were measured by ELISA. Data available included, in addition to anthropometric measurements, sociodemographic and lifestyle characteristics, blood pressure, and biochemical indices (serum insulin, HDL, LDL, TAG, glucose). A HOMA -IR level was used to assess insulin resistance. The International Diabetes Federation criteria were used to classify study participants with MetS. Results: The prevalence of H. pylori infection in the study sample was 52percent (95percent CI, 46.43-57.57). A higher crowding index was associated with a 50percent increase in the odds of infection (OR, 1.41; CI, 1.08-2.27). Blood pressure, waist circumference, serum HDL, LDL, TAG, and glucose levels were comparable between H. pylori positive and negative subjects. The odds of IR and MetS were not significantly different between the two groups. Conclusion: Prevalence of H. pylori infection in Lebanon is comparable to other developing countries. Furthermore, our findings suggested no association of H. pylori infection with IR or MetS. Eradication of H. pylori infection to prevent IR or MetS is not warranted. © 2012 Blackwell Publishing Ltd. |
dc.format.extent |
|
dc.format.extent |
Pages: (444-451) |
dc.language |
English |
dc.publisher |
HOBOKEN |
dc.relation.ispartof |
Publication Name: Helicobacter; Publication Year: 2012; Volume: 17; no. 6; Pages: (444-451); |
dc.source |
Scopus |
dc.title |
Association of H. pylori Infection with Insulin Resistance and Metabolic Syndrome Among Lebanese Adults |
dc.type |
Article |
dc.contributor.affiliation |
Naja, F., Department of Biology, American University of Beirut, Beirut, Lebanon, Members of the Public Health And Nutrition (PHAN), Research Group at the American University of Beirut, Po Box 11-0236, Riad El-Solh Beirut 1107-2020, Lebanon |
dc.contributor.affiliation |
Nasreddine, L., Department of Biology, American University of Beirut, Beirut, Lebanon, Members of the Public Health And Nutrition (PHAN), Research Group at the American University of Beirut, Po Box 11-0236, Riad El-Solh Beirut 1107-2020, Lebanon |
dc.contributor.affiliation |
Hwalla, N., Department of Biology, American University of Beirut, Beirut, Lebanon, Members of the Public Health And Nutrition (PHAN), Research Group at the American University of Beirut, Po Box 11-0236, Riad El-Solh Beirut 1107-2020, Lebanon |
dc.contributor.affiliation |
Moghames, P., Department of Biology, American University of Beirut, Beirut, Lebanon |
dc.contributor.affiliation |
Shoaib, H., Department of Biology, American University of Beirut, Beirut, Lebanon |
dc.contributor.affiliation |
Fatfat, M., Department of Epidemiology and Population Health, American University of Beirut, Beirut, Lebanon |
dc.contributor.affiliation |
Sibai, A., Department of Epidemiology and Population Health, American University of Beirut, Beirut, Lebanon |
dc.contributor.affiliation |
Gali-Muhtasib, H., Department of Epidemiology and Population Health, American University of Beirut, Beirut, Lebanon |
dc.contributor.authorAddress |
Gali-Muhtasib, H.; Department of Nutrition and Food Sciences, American University of Beirut, Beirut, Lebanon; email: amro@aub.edu.lb |
dc.contributor.authorCorporate |
University: American University of Beirut; Faculty: Faculty of Agricultural and Food Sciences; Department: Nutrition and Food Sciences; |
dc.contributor.authorDepartment |
Nutrition and Food Sciences |
dc.contributor.authorDivision |
|
dc.contributor.authorEmail |
amro@aub.edu.lb |
dc.contributor.Faculty |
Faculty of Agricultural and Food Sciences |
dc.contributor.authorInitials |
Naja, F |
dc.contributor.authorInitials |
Nasreddine, L |
dc.contributor.authorInitials |
Hwalla, N |
dc.contributor.authorInitials |
Moghames, P |
dc.contributor.authorInitials |
Shoaib, H |
dc.contributor.authorInitials |
Fatfat, M |
dc.contributor.authorInitials |
Sibai, A |
dc.contributor.authorInitials |
Gali-Muhtasib, H |
dc.contributor.authorOrcidID |
|
dc.contributor.authorReprintAddress |
Gali-Muhtasib, H (reprint author), Amer Univ Beirut, Dept Biol, POB 11-0236, Beirut 11072020, Lebanon. |
dc.contributor.authorResearcherID |
|
dc.contributor.authorUniversity |
American University of Beirut |
dc.description.cited |
Sibai Abla-Mehio, 2008, CVD Prevention and Control, V3, DOI 10.1016-j.precon.2007.06.002; Alberti KGMM, 2009, CIRCULATION, V120, P1640, DOI 10.1161-CIRCULATIONAHA.109.192644; Aslan M, 2006, WORLD J GASTROENTERO, V12, P6865; Aydemir S, 2005, DIGEST DIS SCI, V50, P2090, DOI 10.1007-s10620-005-3012-z; Baum A, 1978, HUMAN RESPONSE CROWD, P3; Beckman JA, 2002, JAMA-J AM MED ASSOC, V287, P2570, DOI 10.1001-jama.287.19.2570; Begue RE, 1999, PEDIATRICS, V103, DOI 10.1542-peds.103.6.e83; Borai A, 2011, BMC MED RES METHODOL, V11, DOI 10.1186-1471-2288-11-158; Central Administration for Statistics and UNDP, 2006, LIV COND HOUS NAT SU, P114; Chedid R, 2009, METABOLISM, V58, P746, DOI 10.1016-j.metabol.2008.11.014; Christodoulou DK, 2011, EUR J INTERN MED, V22, P191, DOI 10.1016-j.ejim.2010.11.010; Danesh J, 1998, BRIT MED J, V316, P1130; deFoneska A, 2010, CURR OPIN GASTROEN, V26, P604, DOI 10.1097-MOG.0b013e32833f1222; Dore MP, 2000, NUTRITION, V16, P407, DOI 10.1016-S0899-9007(00)00267-7; Eshraghian A, 2009, DIGEST DIS SCI, V54, P1966, DOI 10.1007-s10620-008-0557-7; FORMAN D, 1991, BRIT MED J, V302, P1302; Freedman J., 1975, CROWDING BEHAV, P1; Frenck RW, 2003, MICROBES INFECT, V5, P705, DOI 10.1016-S1286-4579(03)00112-6; Gen R, 2010, SOUTH MED J, V103, P190, DOI 10.1097-SMJ.0b013e3181cf373f; Gillum RF, 2004, J NATL MED ASSOC, V96, P1470; Goh KL, 2011, HELICOBACTER, V16, P1, DOI 10.1111-j.1523-5378.2011.00874.x; Gunji T, 2008, AM J GASTROENTEROL, V103, P3005, DOI 10.1111-j.1572-0241.2008.02151.x; Gunji T, 2009, HELICOBACTER, V14, P144, DOI 10.1111-j.1523-5378.2009.00705.x; Haffner SM, 1997, AM J MED, V103, P152; Helfand M, 2009, ANN INTERN MED, V151, P496; Huang BS, 2011, DIGEST DIS SCI, V56, P109, DOI 10.1007-s10620-010-1274-6; Hussein NR, 2010, WORLD J GASTROENTERO, V16, P3226, DOI 10.3748-wjg.v16.i26.3226; Kalaajieh W K, 2000, Sante, V10, P31; Longo-Mbenza B, 2007, INT J CARDIOL, V121, P229, DOI 10.1016-j.ijcard.2006.12.003; Lu Ye-Hsu, 2002, Kaohsiung J Med Sci, V18, P266; Manolakis A, 2007, HELICOBACTER, V12, P287, DOI 10.1111-j.1523-5378.2007.00511.x; MATTHEWS DR, 1985, DIABETOLOGIA, V28, P412, DOI 10.1007-BF00280883; Melki IS, 2004, J EPIDEMIOL COMMUN H, V58, P476, DOI 10.1136-jech.2003.012690; Murray LJ, 1997, INT J EPIDEMIOL, V26, P880, DOI 10.1093-ije-26.4.880; Naja F, 2011, EUR J NUTR, DOI [10.1007-500394-011-0291-3, DOI 10.1007-500394-011-0291-3]; Naja F, 2007, CAN J GASTROENTEROL, V21, P501; Naous Amal, 2007, J Med Liban, V55, P138; Schottker B, 2012, ATHEROSCLEROSIS, V220, P569, DOI 10.1016-j.atherosclerosis.2011.11.029; Sharara AI, 2006, DIGEST LIVER DIS, V38, P829, DOI 10.1016-j.dld.2006.06.040; Steinbach G, 1999, ANN INTERN MED, V131, P88; Suzuki H, 2011, HELICOBACTER, V16, P65, DOI 10.1111-j.1523-5378.2011.00883.x; Uday J., 1987, PSYCHOL CONSEQUENCES, P15; Wang Shao-zhen, 2009, Zhonghua Yi Xue Za Zhi, V89, P958; Woodward M, 2000, J CLIN EPIDEMIOL, V53, P175, DOI 10.1016-S0895-4356(99)00171-7; WOTHERSPOON AC, 1991, LANCET, V338, P1175, DOI 10.1016-0140-6736(91)92035-Z |
dc.description.citedCount |
7 |
dc.description.citedTotWOSCount |
8 |
dc.description.citedWOSCount |
8 |
dc.format.extentCount |
8 |
dc.identifier.articleNo |
|
dc.identifier.coden |
HELIF |
dc.identifier.pubmedID |
23066847 |
dc.identifier.scopusID |
84867702976 |
dc.publisher.address |
111 RIVER ST, HOBOKEN 07030-5774, NJ USA |
dc.relation.ispartOfISOAbbr |
Helicobacter |
dc.relation.ispartOfIssue |
6 |
dc.relation.ispartofPubTitle |
Helicobacter |
dc.relation.ispartofPubTitleAbbr |
Helicobacter |
dc.relation.ispartOfVolume |
17 |
dc.source.ID |
WOS:000310319900006 |
dc.type.publication |
Journal |
dc.subject.otherAuthKeyword |
Cardio-vascular risk factor |
dc.subject.otherAuthKeyword |
epidemiology |
dc.subject.otherAuthKeyword |
prevalence rate |
dc.subject.otherChemCAS |
Glucose, 50-99-7, 84778-64-3 |
dc.subject.otherChemCAS |
insulin, 9004-10-8 |
dc.subject.otherChemCAS |
antibodies, bacterial |
dc.subject.otherChemCAS |
immunoglobulin g |
dc.subject.otherIndex |
Glucose |
dc.subject.otherIndex |
high density lipoprotein cholesterol |
dc.subject.otherIndex |
immunoglobulin g antibody |
dc.subject.otherIndex |
insulin |
dc.subject.otherIndex |
low density lipoprotein cholesterol |
dc.subject.otherIndex |
triacylglycerol |
dc.subject.otherIndex |
adult |
dc.subject.otherIndex |
anthropometric parameters |
dc.subject.otherIndex |
antibody titer |
dc.subject.otherIndex |
article |
dc.subject.otherIndex |
blood pressure |
dc.subject.otherIndex |
blood sampling |
dc.subject.otherIndex |
chemical analysis |
dc.subject.otherIndex |
cholesterol blood level |
dc.subject.otherIndex |
crowding |
dc.subject.otherIndex |
disease association |
dc.subject.otherIndex |
enzyme linked immunosorbent assay |
dc.subject.otherIndex |
female |
dc.subject.otherIndex |
glucose blood level |
dc.subject.otherIndex |
helicobacter infection |
dc.subject.otherIndex |
helicobacter pylori |
dc.subject.otherIndex |
human |
dc.subject.otherIndex |
insulin blood level |
dc.subject.otherIndex |
insulin resistance |
dc.subject.otherIndex |
lebanon |
dc.subject.otherIndex |
lifestyle |
dc.subject.otherIndex |
major clinical study |
dc.subject.otherIndex |
male |
dc.subject.otherIndex |
metabolic syndrome x |
dc.subject.otherIndex |
priority journal |
dc.subject.otherIndex |
seroprevalence |
dc.subject.otherIndex |
socioeconomics |
dc.subject.otherIndex |
triacylglycerol blood level |
dc.subject.otherIndex |
waist circumference |
dc.subject.otherIndex |
adult |
dc.subject.otherIndex |
antibodies, bacterial |
dc.subject.otherIndex |
cross-sectional studies |
dc.subject.otherIndex |
enzyme-linked immunosorbent assay |
dc.subject.otherIndex |
female |
dc.subject.otherIndex |
helicobacter infections |
dc.subject.otherIndex |
helicobacter pylori |
dc.subject.otherIndex |
humans |
dc.subject.otherIndex |
immunoglobulin g |
dc.subject.otherIndex |
insulin resistance |
dc.subject.otherIndex |
lebanon |
dc.subject.otherIndex |
male |
dc.subject.otherIndex |
metabolic syndrome x |
dc.subject.otherIndex |
middle aged |
dc.subject.otherIndex |
prevalence |
dc.subject.otherKeywordPlus |
Coronary-heart-disease |
dc.subject.otherKeywordPlus |
helicobacter-pylori |
dc.subject.otherKeywordPlus |
risk-factors |
dc.subject.otherKeywordPlus |
diabetes-mellitus |
dc.subject.otherKeywordPlus |
japanese population |
dc.subject.otherKeywordPlus |
gastric lymphoma |
dc.subject.otherKeywordPlus |
epidemiology |
dc.subject.otherKeywordPlus |
atherosclerosis |
dc.subject.otherKeywordPlus |
inflammation |
dc.subject.otherKeywordPlus |
prevalence |
dc.subject.otherWOS |
Gastroenterology and Hepatology |
dc.subject.otherWOS |
Microbiology |
dc.identifier.doi |
http://dx.doi.org/10.1111/j.1523-5378.2012.00970.x |